Results 41 to 50 of about 2,500,398 (351)

Prospective clinical assessment of patients with pulmonary arterial hypertension switched from bosentan to macitentan (POTENT)

Pulmonary Circulation, 2022
Even though pulmonary arterial hypertension (PAH) remains an incurable disease, the combination of PAH‐specific therapies allowed treatment strategies to evolve from symptom‐based ones to others that aim to move patients to low‐risk conditions ...
Abdullah M. Aldalaan, Sarfraz A. Saleemi, Ihab Weheba, Abeer Abdelsayed, Maha M. Aleid, Fatima Alzubi, Hamdeia Zaytoun, Nadeen Alharbi   +7 more
doaj   +1 more source

Pulmonary hypertension associated with left-sided heart disease

Swiss Medical Weekly, 2017
Pulmonary hypertension associated with left-sided heart disease (PH-LHD) is the most common type of pulmonary hypertension. In patients with left-sided heart disease, the presence of pulmonary hypertension is typically a marker of more advanced disease,
Micha T. Maeder, Otto D. Schoch, Rebekka Kleiner, Lucas Joerg, Daniel Weilenmann, Swiss Medical Weekly   +5 more
doaj   +1 more source

Non-invasive assessment of pulmonary vascular resistance in pulmonary hypertension: Current knowledge and future direction [PDF]

, 2017
Pulmonary Hypertension (PHT) is relatively common, dangerous and under-recognised. Pulmonary hypertension is not a diagnosis in itself; it is caused by a number of differing diseases each with different treatments and prognoses.
Hills, G, Kuppusamy, H, Naing, P, Playford, D, Scalia, G   +4 more
core   +2 more sources

Hypochromic red cells as a prognostic indicator of survival among patients with systemic sclerosis screened for pulmonary hypertension

Arthritis Research & Therapy, 2023
Background Patients with systemic sclerosis (SSc) are frequently affected by iron deficiency, particularly those with pulmonary hypertension (PH). The first data indicate the prognostic importance of hypochromic red cells (% HRC) > 2% among patients with
Panagiota Xanthouli, Ojan Gordjani, Nicola Benjamin, Satenik Harutyunova, Benjamin Egenlauf, Alberto M. Marra, Simon Haas, Nicklas Milde, Norbert Blank, Hanns-Martin Lorenz, Christoph Fiehn, Silvia Ulrich, Oliver Distler, Ekkehard Grünig, Christina A. Eichstaedt   +14 more
doaj   +1 more source

Tetrahydrobiopterin analogues with NO-dependent pulmonary vasodilator properties [PDF]

, 2011
Reduced NO levels due to the deficiency of tetrahydrobiopterin (BH4) contribute to impaired vasodilation in pulmonary hypertension Due to the chemically unstable nature of BH4 it was hypothesised that oxidatively stable analogues of BR, would be able to ...
Gibson, Colin, Kunuthur, S. P., Milliken, P. H., Suckling, C. J., Wadsworth, R. M.   +4 more
core   +1 more source

Pulmonary Hypertension Due to Left Heart Disease: Diagnosis, Pathophysiology, and Therapy.

HYPERTENSION, 2020
Pulmonary hypertension (PH) due to left heart disease (LHD) is the most common type of PH and is defined as mean pulmonary artery systolic pressure of >20 mm Hg and pulmonary capillary wedge pressure >15 mm Hg during right heart catheterization.
M. Al-Omary, S. Sugito, A. Boyle, A. Sverdlov, N. Collins   +4 more
semanticscholar   +1 more source

The patient experience of pulmonary hypertension: a large cross-sectional study of UK patients

BMC Pulmonary Medicine, 2019
Background Pulmonary Hypertension Association UK (PHA-UK) is the only charity in the UK especially for people affected by pulmonary hypertension (PH).
Iain Armstrong, Catherine Billings, David G. Kiely, Janelle Yorke, Carl Harries, Shaun Clayton, Wendy Gin-Sing   +6 more
doaj   +1 more source

Short-term hemodynamic effects of apelin in patients with pulmonary arterial hypertension [PDF]

, 2018
Apelin agonism causes systemic vasodilatation and increased cardiac contractility in humans, and improves pulmonary arterial hypertension (PAH) in animal models.
Alastalo, Apostolopoulou, Ashley, Barnes, Berry, Brame, Cheng, Dai, Falcao-Pires, Grimminger, Japp, Japp, Jing, Kleinz, Lee, Machado, McLaughlin, Morrell, Petkov, Salcedo, Sulica, Tatemoto, Tatemoto, Voswinckel   +23 more
core   +4 more sources

Definition, classification and diagnosis of pulmonary hypertension

European Respiratory Journal
Pulmonary hypertension (PH) is a haemodynamic condition characterised by elevation of mean pulmonary arterial pressure (mPAP) >20 mmHg, assessed by right heart catheterisation.
Gabor Kovacs, Sonja Bartolome, C. Denton, M. A. Gatzoulis, Sue Gu, Dinesh Khanna, David B. Badesch, D. Montani   +7 more
semanticscholar   +1 more source

Pulmonary hypertension

Nature Reviews Disease Primers
Pulmonary hypertension encompasses a range of conditions directly or indirectly leading to elevated pressures within the pulmonary arteries. Five main groups of pulmonary hypertension are recognized, all defined by a mean pulmonary artery pressure of >20 mmHg: pulmonary arterial hypertension (rare), pulmonary hypertension associated with left-sided ...
Ana Mocumbi, Marc Humbert, Anita Saxena, Zhi-Cheng Jing, Karen Sliwa, Friedrich Thienemann, Stephen L. Archer, Simon Stewart   +7 more
openaire   +3 more sources