Results 21 to 30 of about 2,534,413 (315)
Cardiovascular Research, 2018 Aims Renal inflammation, leading to fibrosis and impaired function is a major contributor to the development of hypertension. The NLRP3 inflammasome mediates inflammation in several chronic diseases by processing the cytokines pro-interleukin (IL)-1β and
S. Krishnan +17 more
semanticscholar +1 more source
Physiological Reports, 2021 In hypertension induced by angiotensin II (AngII) administration with high salt (HS) intake, intrarenal angiotensinogen (AGT) and tumor necrosis factor‐alpha (TNF‐α) levels increase.
Dewan S. A. Majid +4 more
doaj +1 more source
Survival Analysis of Hemodialysis Patients [PDF]
, 2016 Survival analysis as a collection of statistical procedures for analyzing the data that its outcome variable was the time to occurrence of an event. Kaplan-Meier method is a type of survival analysis technique, this method is often called the Product ...
Ardianto, E. T. (Efri) +2 more
core +2 more sources
Role of the Sympathetic Nervous System and Its Modulation in Renal Hypertension
Frontiers in Medicine, 2018 The kidneys are densely innervated with renal efferent and afferent nerves to communicate with the central nervous system. Innervation of major structural components of the kidneys, such as blood vessels, tubules, the pelvis, and glomeruli, forms a ...
Y. Sata +4 more
semanticscholar +1 more source
Obesity-induced hypertension: interaction of neurohumoral and renal mechanisms.
Circulation Research, 2015 Excess weight gain, especially when associated with increased visceral adiposity, is a major cause of hypertension, accounting for 65% to 75% of the risk for human primary (essential) hypertension.
J. Hall +4 more
semanticscholar +1 more source
Signaling pathways involved in renal oxidative injury: role of the vasoactive peptides and the renal dopaminergic system [PDF]
, 2014 The physiological hydroelectrolytic balance and the redox steady state in the kidney are accomplished by an intricate interaction between signals from extrarenal and intrarenal sources and between antinatriuretic and natriuretic factors.
Choi, Marcelo Roberto +6 more
core +3 more sources
Association Between Blood Pressure and Adverse Renal Events in Type 1 Diabetes. [PDF]
, 2016 ObjectiveTo compare different blood pressure (BP) levels in their association with the risk of renal outcomes in type 1 diabetes and to determine whether an intensive glycemic control strategy modifies this association.Research design and methodsWe ...
Gitelman, Stephen E +5 more
core +2 more sources
Rehydration with fructose worsens dehydration-induced renal damage
BMC Nephrology, 2018 Background Increasing evidence suggests heat stress induced chronic kidney disease (CKD) may be mediated by endogenous fructose generation and may be exacerbated by rehydration by fructose-containing solutions.
Tamara Milagres +12 more
doaj +1 more source
Metformin does not slow cyst growth in the PCK rat model of polycystic kidney disease
Physiological Reports, 2023 Metformin (MET) has the potential to activate p‐AMPK and block mTORC1‐induced proliferation of tubular cells in PKD kidneys. The aim of this study was to determine the effects of MET on cyst growth, kidney function, AMPK and mTOR signaling, and lactate ...
Ozgur A. Oto +6 more
doaj +1 more source
Associations of Perirenal Fat Thickness with Renal and Systemic Calcified Atherosclerosis. [PDF]
, 2020 BackgroundWe investigated associations between perirenal fat thickness and atherosclerotic calcification in six different vascular beds.MethodsUsing a community-based cohort (n=3,919), perirenal fat thickness was estimated from computed tomography scans.
Allison, Matthew A +4 more
core