Results 61 to 70 of about 2,600,943 (336)

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Improved agreement and diagnostic accuracy of a cuffless 24-h blood pressure measurement device in clinical practice

Scientific Reports, 2021
A cuffless blood pressure (BP) device (TestBP) using pulse transit time is in clinical use, but leads to higher BP values compared to a cuff-based 24 h-BP reference device (RefBP).
Thenral Socrates, Philipp Krisai, Annina S. Vischer, Andrea Meienberg, Michael Mayr, Thilo Burkard   +5 more
doaj   +1 more source

Association Between High Perceived Stress Over Time and Incident Hypertension in Black Adults: Findings From the Jackson Heart Study. [PDF]

, 2019
Background Chronic psychological stress has been associated with hypertension, but few studies have examined this relationship in blacks. We examined the association between perceived stress levels assessed annually for up to 13 years and incident ...
Abdalla, Marwah, Allison, Matthew, Blackshear, Chad, Butler, Mark J, Castañeda, Sheila F, Kalinowski, Jolaade, Langford, Aisha T, Ogedegbe, Gbenga, Shimbo, Daichi, Sims, Mario, Spruill, Tanya M, Tajeu, Gabriel S, Thomas, S Justin   +12 more
core  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Non-dipping blood pressure pattern is associated with higher risk of new-onset diabetes in hypertensive patients with obstructive sleep apnea: UROSAH data

Frontiers in Endocrinology, 2023
ObjectiveImpairment of circadian blood pressure (BP) patterns has been associated with cardiovascular risks and events in individuals with hypertension and in general populations, which are more likely to be found in obstructive sleep apnea (OSA).
Qin Luo, Qin Luo, Qin Luo, Nanfang Li, Nanfang Li, Nanfang Li, Qing Zhu, Qing Zhu, Qing Zhu, Xiaoguang Yao, Xiaoguang Yao, Xiaoguang Yao, Menghui Wang, Menghui Wang, Menghui Wang, Mulalibieke Heizhati, Mulalibieke Heizhati, Mulalibieke Heizhati, Xintian Cai, Xintian Cai, Xintian Cai, Junli Hu, Junli Hu, Junli Hu, Ayinigeer Abulimiti, Ayinigeer Abulimiti, Ayinigeer Abulimiti, Ling Yao, Ling Yao, Ling Yao, Xiufang Li, Xiufang Li, Xiufang Li, Lin Gan, Lin Gan, Lin Gan   +35 more
doaj   +1 more source

Redox signaling, Nox5 and vascular remodeling in hypertension [PDF]

, 2015
Purpose of review: Extensive data indicate a role for reactive oxygen species (ROS) and redox signaling in vascular damage in hypertension. However, molecular mechanisms underlying these processes remain unclear, but oxidative post-translational ...
De Lucca Camargo, Livia, Dulak-Lis, Maria, Harvey, Adam, Montezano, Augusto C., Touyz, Rhian M., Tsiropoulou, Sofia   +5 more
core   +1 more source

Mechanical Thrombectomy for TRACE‐III‐Eligible Patients With Ischemic Stroke: A Multicenter Retrospective Study Compared to TRACE‐III and TIMELESS Trials

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The results of the TRACE‐III trial demonstrated that tenecteplase (TNK) might be comparable to TNK combined with mechanical thrombectomy (MT) for large vessel occlusion (LVO) stroke within 4.5 to 24 h of onset, as tested in the TIMELESS trial.
Chongyang Huang, Yanru Liu, Jiangang Zhang, Sheng Guan, Tao Quan, Zhen Chen, Xiaojie Fu, Sen Wei, Kaihao Han, Xiaoan Zhou, Chengcheng Zhu, Edgar Samaniego, Yueqi Zhu, Haowen Xu   +13 more
wiley   +1 more source

Comparação de critérios diagnósticos de insuficiência renal aguda em cirurgia cardíaca

Arquivos Brasileiros de Cardiologia, 2013
FUNDAMENTO: Há grande controvérsia quanto ao diagnóstico de Insuficiência Renal Aguda (IRA), existindo mais de 30 diferentes definições. OBJETIVO: Avaliar a incidência e os fatores de risco para desenvolvimento de IRA no pós-operatório de cirurgia ...
Márcio Campos Sampaio, Carlos Alberto Gonçalves Máximo, Carolina Moreira Montenegro, Diandro Marinho Mota, Tatiana Rocha Fernandes, Antonio Carlos Mugayar Bianco, Celso Amodeo, Antonio Carlos Cordeiro   +7 more
doaj   +1 more source

Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova, Teresa Fazia, Giovanni Di Caprio, Davide Gentilini, Luisa Bernardinelli, Roberto Bergamaschi   +5 more
wiley   +1 more source

Pheochromocytoma/Paraganglioma (PPGL): A Misdiagnosed Cause of Hypertension during Pregnancy

Case Reports in Obstetrics and Gynecology
Hypertension (HT) during pregnancy is not an infrequent obstetric problem, reaching a prevalence of 5-10%. This condition is highly associated with both maternal and fetal complications if not precisely diagnosed and managed.
Rafael Buck Giorgi, Priscila Teixeira Aroucha, Thalissa M. Favreto, Micaela F. Montero, Julia M. F. Velloni, Ilana Korkes, Elisa Napolitano Ferreira, Caroline Olivati, Jose Viana Lima, Claudio E. Kater, Flavia A. Costa-Barbosa   +10 more
doaj   +1 more source