Results 61 to 70 of about 3,462,966 (385)

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Hypertension

South African Family Practice, 2011
No Abstract.
openaire   +3 more sources

Association of Renin-Angiotensin System Inhibitors With Severity or Risk of Death in Patients With Hypertension Hospitalized for Coronavirus Disease 2019 (COVID-19) Infection in Wuhan, China.

JAMA cardiology, 2020
Importance Data are lacking whether patients with hypertension who are taking angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) have increased severity or risk of mortality during hospitalization for coronavirus ...
Juyi Li, Xiufang Wang, Jian Chen, Hongmei Zhang, A. Deng   +4 more
semanticscholar   +1 more source

Resistant arterial hypertension in a patient with adrenal incidentaloma multiple steno-obstructive vascular lesions and antiphospholipid syndrome [PDF]

, 2015
Resistant hypertension is defined as above of blood pressure (≤ 140/90 mmHg) despite therapy with three or more antihypertensive drugs of different classes at maximum tolerable doses with one bling a diuretic.
CONCISTRE, ANTONIO, Gambale, G., IANNUCCI, Gino, Letizia, C., MARINELLI, CRISTIANO, PETRAMALA, LUIGI, Toma, G. De, Vincentis, G. De, ZACCARIA, Alvaro   +8 more
core  

Sources of dietary protein and risk of hypertension in a general Dutch population [PDF]

, 2012
Evidence suggests a small beneficial effect of dietary protein on blood pressure (BP), especially for plant protein. We examined the relationship between several types of dietary protein (total, plant, animal, dairy, meat and grain) and the risk of ...
Altorf-van der Kuil, W., Boer, J.M.A., Engberink, M.F., Geleijnse, J.M., Verschuren, W.M.M.   +4 more
core   +2 more sources

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Enhanced Mitochondrial Transient Receptor Potential Channel, Canonical Type 3–Mediated Calcium Handling in the Vasculature From Hypertensive Rats

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundMitochondrial Ca2+ homeostasis is fundamental to the regulation of mitochondrial reactive oxygen species (ROS) generation and adenosine triphosphate production.
Bin Wang, Shiqiang Xiong, Shaoyang Lin, Weijie Xia, Qiang Li, Zhigang Zhao, Xing Wei, Zongshi Lu, Xiao Wei, Peng Gao, Daoyan Liu, Zhiming Zhu   +11 more
doaj   +1 more source

Improved agreement and diagnostic accuracy of a cuffless 24-h blood pressure measurement device in clinical practice

Scientific Reports, 2021
A cuffless blood pressure (BP) device (TestBP) using pulse transit time is in clinical use, but leads to higher BP values compared to a cuff-based 24 h-BP reference device (RefBP).
Thenral Socrates, Philipp Krisai, Annina S. Vischer, Andrea Meienberg, Michael Mayr, Thilo Burkard   +5 more
doaj   +1 more source

Status of Hypertension in China: Results From the China Hypertension Survey, 2012–2015

Circulation, 2018
Background: Although the prevalence of hypertension (HTN) continues to increase in developing countries, including China, recent data are lacking. A nationwide survey was conducted from October 2012 to December 2015 to assess the prevalence of HTN in ...
Zengwu Wang, Zuo Chen, Linfeng Zhang, Xin Wang, G. Hao, Zugui Zhang, L. Shao, Ye Tian, Ying Dong, Congyi Zheng, Jiali Wang, Man-lu Zhu, W. Weintraub, R. Gao   +13 more
semanticscholar   +1 more source

An Initiative to Educate and Support Young Adults Diagnosed with Hypertension [PDF]

, 2020
An Initiative to Educate and Support Young Adults Diagnosed with Hypertension Page Tomlinson, BS, RN, DNPc Background: Hypertension is a common diagnosis in the US with significant long-term effects.
Tomlinson, Page
core   +1 more source