Results 51 to 60 of about 490,601 (215)

Preoperative Frailty as a Predictor of Quality of Life Outcomes Following Cytoreductive Surgery

World Journal of Surgery, EarlyView.
Frailty has emerged as a critical determinant of postoperative risk in patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS + HIPEC). However, its impact on postoperative quality of life (QoL) remains underexplored.
Zirong Bai, Laura Barker, Rihan Shahab, Cherry Koh, Michael Solomon, Kate Alexander, Sascha Karunaratne, Nabila Ansari, Leani Souza Maximo Pereira, Ana Paula Drummond Lage, Daniel Steffens   +10 more
wiley   +1 more source

Drain site enterocutaneous fistula after hyperthermic intraperitoneal chemotherapy

, 2021
Spontaneous sigmoid colon perforation after cytoreduction surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) is a rare complication. It is more commonly seen with mitomycin‐based HIPEC. This case study's patient presented with pus discharge at
Navin Kumar, Mukur Dipi Ray, Kanak Lata
core   +1 more source

Combining TAG‐72CAR with anti‐MUC16CAR improves the potency of ovarian cancer treatment

The FEBS Journal, EarlyView.
Tz‐KBBCAR, a combinatorial CAR targeting MUC16 and TAG‐72, enhances the precision of ovarian cancer immunotherapy. By requiring both tumour antigens for full activation, Tz‐KBBCAR was designed to eliminate MUC16+/TAG‐72+ cancer cells, while sparing MUC16+/TAG‐72‐ healthy cells.
Alicia Villatoro, Aurore Dougé, Klara Krpina, Lea‐Marie Schmitz, Christopher Forcados, Fatemeh Kaveh, Andrea Estrella Arias‐Díaz, Pascal Gelebart, Emmet McCormack, Renata Stripecke, Miguel Abal, Ben Davidson, Else Marit Inderberg, Sébastien Wälchli   +13 more
wiley   +1 more source

Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Surface Malignancies: Learning Curve Based on Surgical and Oncological Outcomes

, 2020
Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is a complex, highly specialized procedure used to treat peritoneal surface malignancies (PSM) [...
Wojciech P. Polkowski, Jerzy Mielko, Karol Rawicz-Pruszyński, Katarzyna Sędłak, Katarzyna Gęca, Magdalena Kwietniewska   +5 more
core   +1 more source

Polish clinical practice guidelines on Hyperthermic Intraperitoneal Chemotherapy (HIPEC) with Cytoreductice Surgery (CRS) in peritoneal malignancy treatment [PDF]

, 2015
Leczenie nowotworów powierzchni otrzewnej stanowi istotny problem w onkologii. Wykazano, że skojarzenie maksymalnej cytoredukcji chirurgicznej z dootrzewnową chemioterapią w hipertermii (HIPEC; hyperthermic intraoperative peritoneal chemotherapy) może ...
Rutkowski, Piotr, Polkowski, Wojciech, Herman, Krzysztof, Zegarski, Wojciech, Wyrwicz, Lucjan, Jastrzębski, Tomasz, Kładny, Józef, Krzakowski, Maciej, Zdzienicki, Marcin, Wysocki, Piotr, Śpiewankiewicz, Beata, Kojs, Zbigniew   +11 more
core   +1 more source

Inhibition of P‐glycoprotein using photoimmunotherapy in peritoneal metastasis mouse model

Photochemistry and Photobiology, EarlyView.
Photoimmunotherapy (PIT) using photoimmunoconjugates (PICs) can inhibit the function of the ATP‐binding cassette (ABC) transporter P‐glycoprotein (P‐gp) in a mouse model of peritoneal carcinomatosis. Sterile‐filtered PIC was administered in vivo via intraperitoneal (IP) injection 20 days after IP tumor cell implantation of P‐gp‐overexpressing NCI/ADR ...
Kaitlyn A. Moore, Brian Schnoor, Kathryn L. McNaughton, Idrisa Rahman, Benjamin D. Powers, Dana M. Roque, Huang‐Chiao Huang   +6 more
wiley   +1 more source

Hyperthermic intraperitoneal chemotherapy (HIPEC) as another treatment modality for desmoplastic round cell tumour patients: first paediatric experience from UK

, 2021
We present the first young paediatric patient with desmoplastic small round cell tumour (DSRCT) treated in UK with hyperthermic intraperitoneal chemotherapy (HIPEC).
Cecil, T, Angelini, P, Chisholm, JC, Okoye, B, Dayal, S, Sjoberg, Bexelius T   +5 more
core   +2 more sources

Epidemiological and Prognostic Differences in Malignant Mesothelioma Between Eastern China and SEER Database

Cancer Science, Volume 117, Issue 11, Page 3146-3159, November 2026.
For long years, patients and clinicians in Eastern China used Western data as information foundation for management and treatment of malignant mesothelioma, due to its rarity and lack of deep investigation. This study updated the epidemiological data of malignant mesothelioma in Eastern China, and revealed better survival outcomes compared to Western ...
Ningning Li, Ruting Wang, Wenya Zhang, Zulei Shao, Hongyu Lin, Guanai Bao, Weimin Mao, Zhongjian Chen   +7 more
wiley   +1 more source

Incisional hernia formation can be reduced following hyperthermic intraperitoneal chemotherapy with increased suture length to wound length ratio fascial closure

International Journal of Abdominal Wall and Hernia Surgery, 2020
INTRODUCTION: Incisional hernia (IH) is a common postsurgical complication of laparotomy. The impact of hyperthermic intraperitoneal chemotherapy on fascial healing has not been evaluated.
Joseph A Lewcun, Eric M Pauli, Colette Pameijer   +2 more
doaj   +1 more source

Standardizing Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer Treatment: Navigating Complexities and Charting the Path Forward [PDF]

The incorporation of hyperthermic intraperitoneal chemotherapy (HIPEC) into the treatment landscape for ovarian cancer has invoked a spectrum of emotions, ranging from enthusiastic anticipation to cautious skepticism [...
Pedro Cascales-Campos, Juan José Segura-Sampedro, Segura-Sampedro, Juan José, Cascales-Campos, Pedro   +3 more
core   +1 more source