Results 51 to 60 of about 242,932 (222)

Mannitol versus hypertonic saline for intra-operative brain relaxation during aneurysm surgery

Journal of Neuroanaesthesiology and Critical Care, 2015
Background: The study was designed to compare the effects of equiosmolar and equivolemic 3% hypertonic saline (HTS) and 20% mannitol (M) on brain relaxation during aneurysm surgery. Materials and Methods: A prospective, randomised, double-blind study was
Shalini Sharma, Vinod K. Grover, Preethy J. Mathew   +2 more
doaj   +1 more source

Modular Polymers With Tuneable Charge and Amphiphilicity for Effective Antimicrobial Photodynamic Therapy

Macromolecular Rapid Communications, EarlyView.
A modular dual‐strategy platform combining free radical copolymerisation and post‐polymerisation modification yields a library of ruthenium‐functionalised polymers for antimicrobial photodynamic therapy. Tuneable composition and net charge govern activity against multidrug‐resistant Pseudomonas aeruginosa biofilms and Staphylococcus aureus under ...
Ali Balasini, Jannik Fryn, Margaux Bonnardot, Jérémy Godard, Tristan Montier, Gilles Lemercier, Franck Thétiot, Tony Le Gall, Ulrich Jonas   +8 more
wiley   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

The Usefulness of Machine Learning Models to Predict Patient‐Reported Outcome Measures in Chronic Rhinosinusitis With Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background and Objective The treatment available for chronic rhinosinusitis with nasal polyps (CRSwNP) has remained unsatisfactory. Patient‐reported outcome measures (PROMs), capturing patient‐perceived health status and well‐being, are vehicles for measuring and improving the efficacy of care.
Yang Shen, Pan‐Hui Xiong, Bo‐Wen Zheng, Chen‐Xi Li, Jun‐Liang Chen, Yue Gu, Yan‐Han Yang, Tao Lu, Yu‐Cheng Yang   +8 more
wiley   +1 more source

Alkalinised lidocaine as an anaesthetic before onabotulinumtoxinA injections. a randomised trial

BJU International, Volume 135, Issue 4, Page 638-647, April 2025.
Objectives To evaluate the effect of intravesical alkalinised lidocaine as an anaesthetic treatment on procedural pain during intradetrusor onabotulinumtoxinA (BTX‐A) injections for overactive bladder. Patients and Methods This single‐centre, randomised, double‐blind, placebo‐controlled two period crossover trial was conducted on women scheduled for ...
Meryam El Issaoui, Marlene Elmelund, Niels Klarskov   +2 more
wiley   +1 more source

Intrarenal hypertonic saline infusions in dogs with thoracic caval constriction [PDF]

, 1987
Intrarenal hypertonic saline infusions in dogs with thoracic caval constriction. Intrarenal artery infusions of hypertonic saline can activate tubuloglomerular feedback (TGF), decreasing renal blood flow (RBF) and glomerular filtration rate (GFR).
Jackson, Edwin K., Gerkens, John F., Heidemann, Hugo T.H., Branch, Robert A.   +3 more
core   +1 more source

Effect of hypertonic saline in patients with traumatic brain injury

, 2022
To date, it remains difficult for physicians to make informed decisions about which concentration of hypertonic saline is more effective for treating patients with traumatic brain injury.
Xing Wang
core   +1 more source

Effect of hypertonic saline treatment on the inflammatory response after hydrochloric acid-induced lung injury in pigs

Clinics, 2015
OBJECTIVES:Hypertonic saline has been proposed to modulate the inflammatory cascade in certain experimental conditions, including pulmonary inflammation caused by inhaled gastric contents. The present study aimed to assess the potential anti-inflammatory
Carla Augusto Holms, Denise Aya Otsuki, Marcia Kahvegian, Cristina Oliveira Massoco, Denise Tabacchi Fantoni, Paulo Sampaio Gutierrez, Jose Otavio Costa Auler Junior   +6 more
doaj   +1 more source

Cholinergic inputs to motoneurons in the spinal cord augment focal muscle spasticity in rodents

British Journal of Pharmacology, EarlyView.
Background and Purpose Cholinergic premotor inputs to motoneurons support high levels of motor output when required. However, the possible role of these inputs in pathologically elevated muscle tone has not been characterised. To address this, we examined the modulatory effect of spinal acetylcholine (ACh) on experimental spastic paralysis ...
Patrik Meglić, Petra Šoštarić, Eirini Tsape, Melpomeni Galani, Ana Knezović, Laura Restani, Marco Pirazzini, Ornella Rossetto, Gareth B. Miles, Laskaro Zagoraiou, Ivica Matak   +10 more
wiley   +1 more source

Experimentally-induced low back pain from hypertonic saline injections into lumbar interspinous ligament and erector spinae muscle

, 2010
Injection of hypertonic saline into back muscles or ligaments can induce acute low back pain (LBP). However, no study has systematically investigated pain characteristics from these structures.
Coppieters, Michel W, Tsao, H, Hodges, Paul W, Coppieters, MW, Tucker, KJ, Tucker, Kylie J, Tsao, Henry, Hodges, PW   +7 more
core   +1 more source