Results 41 to 50 of about 242,932 (222)

Self‐Propelled HPB@Lip@AB Nanomotors Ameliorate Dry Eye Disease

Advanced Science, EarlyView.
A self‐propelled HPB@Lip@AB nanomotor system is developed for dry eye disease (DED) therapy, facilitating rapid penetration across ocular surface barriers while integrating hydrogen therapy with multi‐enzyme‐like antioxidant activity. The nanoplatform restores mitochondrial function, suppresses oxidative stress, inflammation, and apoptosis, and ...
Jing Li, Xi Wan, Xinru Su, Zechuan Li, Yue Wang, Ying Wang, Ruofei Li, Huangzhao Wei, Jianbin Zhang, Shuai Wang   +9 more
wiley   +1 more source

The comparison between steroid and hypertonic saline 10% with steroid in transforaminal epidural injection in patients with unilateral foraminal stenosis [PDF]

International Clinical Neuroscience Journal, 2015
Background: Chronic radicular low back pain is a common disease that limits patient’s daily activity. Epidural steroid injection is becoming the mainstay of therapies for radicular low back pain due to contained bulged disc.
Behnam Hosseini, Mohammad Hossein Ataei, Sirous Momenzadeh, Reza Jalili Khoshnood, Davood Ommi   +4 more
doaj   +1 more source

Targeted Mechanogenetics to Modulate Specific Deep Neural Circuits

Advanced Science, EarlyView.
This study introduces mechanogenetics, a nanobubble‐enhanced sonogenetic strategy for selective modulation of feeding‐related neural circuits in the mouse lateral hypothalamus. Mechanogenetic stimulation modulates feeding behavior through glutamatergic projections from the lateral hypothalamus to the ventral tegmental area, highlighting its potential ...
Xuandi Hou, Jianing Jing, Zhuohan Shi, Lei Sun   +3 more
wiley   +1 more source

Hypertonic Saline for Hyponatremia [PDF]

Clinical Journal of the American Society of Nephrology, 2007
Data regarding dosage-response relationships for using hypertonic saline in treatment of hyponatremia are extremely limited. Objectives of this study were to assess adherence to previously published guidelines (limiting correction to 18 mEq/L per 48 h. No patient's rate was corrected by >25 mEq/L per 48 h. Among patients with serum sodium
Hashim K, Mohmand, Dany, Issa, Zubair, Ahmad, Joseph D, Cappuccio, Ruth W, Kouides, Richard H, Sterns   +5 more
openaire   +2 more sources

Dual‐Dynamically Crosslinked Nanogels Enable Prolonged Ocular Retention for Multimodal Dry Eye Therapy

Advanced Science, EarlyView.
This berberine‐loaded dual‐dynamically crosslinked nanogel integrates tannic acid‐zinc metal‐phenolic networks and carboxymethyl chitosan/aldehyde‐functionalized poly(ethylene glycol) dynamic Schiff base networks, achieving 1‐year colloidal and antioxidant stability, sustained corneal berberine exposure for 24 h to support convenient once‐daily dosing,
Yanru Xin, Sisi Chen, Shengli Huang, Mengqi Huang, Jingyan Zhu, Zijian Wang, Jianliang Shen, Qinxiang Zheng   +7 more
wiley   +1 more source

The interaction and pharmacological modulation of the cardiorespiratory responses to primary thoracic blast injury, haemorrhage resuscitation [PDF]

, 2002
Blast injuries represent a problem for civilian and military populations. The response to thoracic blast injury involves a reflex bradycardia, hypotension and apnoea.
Sawdon, Mariana Annette, Sawdon, Marina Annette, Sawdon, Marina   +2 more
core  

Hypertonic saline for fluid resuscitation in ICU patients post-cardiac surgery (HERACLES): a double-blind randomized controlled clinical trial. [PDF]

, 2020
PURPOSE Recent evidence questions a liberal approach to fluid resuscitation in intensive care unit (ICU) patients. Here, we assess whether use of hypertonic saline applied as single infusion at ICU admission after cardiac surgery can reduce cumulative
Zuercher, Patrick, Hess, Benjamin, Waskowski, Jan, Messmer, Anna S., Wenger, Stefanie, Jakob, Laura, Stoehr, Frederik, Englberger, Lars, Kindler, Manuel, Schefold, Joerg C., Jakob, Stephan M., Pfortmüller, Carmen A., Schenk, Noelle   +12 more
core   +2 more sources

Mechanism study of an articular cartilage repair material and its forward‐looking test for space medicine

BMEMat, EarlyView.
The regeneration process following dLhCG engraftment progressed through four distinct and interconnected stages. dLhCG maintained its regenerative efficacy after 6 months of cosmic exposure, supporting its potential application in space medicine.
Xu Hu, Hang Yao, Zhen Zhang, Zhonglian Wu, Huiqun Zhou, Bangheng Liu, Liang Ma, Yulei Mu, Dong‐An Wang   +8 more
wiley   +1 more source

Salbutamol Nebulisation in Normal Saline versus Salbutamol Nebulisation in Hypertonic Saline (3%) in Children with Acute Asthma Exacerbation: An Open-labelled Randomised Controlled Trial [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Asthma has a significant impact and is the leading cause of morbidity and mortality in children. Salbutamol has been the cornerstone of treatment for bronchial constriction in asthma.
Mohanlal Kundu, Kapil Bhalla, Dinkar Yadav, Hunny Verma, Neeraj Kumar, Mukesh Saini, Mohit Yadav, Neha Yadav   +7 more
doaj   +1 more source

Trendelenburg positioning with or without norepinephrine infusion for haemodynamic support in anaesthetised hypovolemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Intraoperative haemorrhage during equine anaesthesia is a rare but potentially fatal complication requiring prompt haemodynamic support. Postural manoeuvres such as Trendelenburg (TL) positioning and vasopressor support augment venous return and improve cardiac output (CO), yet their efficacy in anaesthetised hypovolemic horses ...
Vaidehi V. Paranjape, Klaus Hopster, Ismar Lutvikadic, Bernd Driessen   +3 more
wiley   +1 more source