Results 31 to 40 of about 242,932 (222)

Epinephrine Improves the Efficacy of Nebulized Hypertonic Saline in Moderate Bronchiolitis: A Randomised Clinical Trial.

PLoS ONE, 2015
Background and aimsThere is no evidence that the epinephrine-3% hypertonic saline combination is more effective than 3% hypertonic saline alone for treating infants hospitalized with acute bronchiolitis. We evaluated the efficacy of nebulized epinephrine
J Carlos Flores-González, Miguel A Matamala-Morillo, Patricia Rodríguez-Campoy, Juan J Pérez-Guerrero, Belén Serrano-Moyano, Paloma Comino-Vazquez, Encarnación Palma-Zambrano, Rocio Bulo-Concellón, Vanessa Santos-Sánchez, Alfonso M Lechuga-Sancho, Bronchiolitis of Cadiz Study group (BronCaS)   +10 more
doaj   +1 more source

Mechanisms and applications of hypertonic saline [PDF]

Journal of the Royal Society of Medicine, 2011
Hypertonic saline is a strong sterile solution of salt water that can be inhaled as a nebulized medication for people with cystic fibrosis (CF). To examine how it should be applied clinically, it is worth considering the mechanisms by which it affects the disease process, and which signs, symptoms and other clinical outcomes it influences.
Mark R, Elkins, Peter T P, Bye
openaire   +2 more sources

Arginine or Hypertonic Saline-Stimulated Copeptin to Diagnose AVP Deficiency. [PDF]

, 2023
BACKGROUND: Distinguishing between arginine vasopressin (AVP) deficiency and primary polydipsia is challenging. Hypertonic saline-stimulated copeptin has been used to diagnose AVP deficiency with high accuracy but requires close sodium monitoring ...
Soares, Beatriz S, Hofland, Johannes, Erlic, Zoran; https://orcid.org/, Widmer, Andrea, Atila, Cihan; https://orcid.org/, Christ-Crain, Mirjam, Sailer, Clara O; https://orcid.org/, Indirli, Rita, Beuschlein, Felix, Winzeler, Bettina; https://orcid.org/, Gurnell, Mark, Chifu, Irina, Felder, Susan, Fassnacht, Martin; https://orcid.org/, Drummond, Juliana B, Vogt, Deborah R, Hutter, Nina, Ferrante, Emanuele, Refardt, Julie; https://orcid.org/, Drexhage, Roosmarijn C, Powlson, Andrew S   +20 more
core   +4 more sources

Randomised controlled trials may underestimate drug effects: balanced placebo trial design.

PLoS ONE, 2014
BackgroundIt is an inherent assumption in randomised controlled trials that the drug effect can be estimated by subtracting the response during placebo from the response during active drug treatment.ObjectiveTo test the assumption of additivity.
Karen Lund, Lene Vase, Gitte L Petersen, Troels S Jensen, Nanna B Finnerup   +4 more
doaj   +1 more source

Effects of hypertonic saline solution associated to remote ischemic perconditioning in kidney ischemia/reperfusion injury in rats [PDF]

Acta Cirúrgica Brasileira, 2017
Purpose: To evaluate the effects of hypertonic saline solution associated to remote ischemic perconditioning in renal ischemia/reperfusion injury in rats. Methods: Twenty five male rats (Wistar) underwent right nephrectomy and were distributed into five
Marcus Vinicius Henriques Brito, Edson Yuzur Yasojima, Sandro Percário, Rubens Fernando Gonçalves Ribeiro Júnior, Lainy Carollyne da Costa Cavalcante, Andrew Moraes Monteiro, Rodrigo Paracampo Couteiro, Ivone Aline da Silva Rodrigues, Hellen Aparecida Geyer dos Santos   +8 more
doaj   +1 more source

Equiosmolar doses of hypertonic saline versus mannitol for brain relaxation in patients undergoing elective craniotomies: an updated systematic review and meta-analysis

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2022
Background Hypertonic saline and mannitol are hyperosmolar agents frequently used to lower ICP and relax the brain during surgeries. Several methods have been used to achieve a good and relaxed brain, such as hyperventilation, cerebrospinal fluid ...
Theodorus Kevin Putra Johansyah, Jeremy Jonathan, I. G. A. A. Andra Yusari, John Nolan, Alif Hakim Alamsyah, Geizar Arsika Ramadhana   +5 more
doaj   +1 more source

Clinical review : hypertonic saline resuscitation in sepsis [PDF]

, 2002
The present review discusses the hemodynamic effects of hypertonic saline in experimental shock and in patients with sepsis. We comment on the mechanisms of action of hypertonic saline, calling upon data in hemorrhagic and septic shock.
Oliveira, Roselaine Pinheiro de, Soriano, Francisco Garcia, Velasco, Irineu Tadeu, Friedman, Gilberto   +3 more
core   +1 more source

Hypertonic saline in ICU setting: what is its position? A systematic review and empirical analysis

Ain Shams Journal of Anesthesiology, 2022
Background Fluid overload has been linked to poor outcomes in the critically ill in recent years, with multiple studies showing an increase in mortality in the overall intensive care unit population.
Marco Dornelles, Erik P. Dornelles, Larissa P. Dornelles   +2 more
doaj   +1 more source

Hypertonic Saline for Hyponatremia: Meeting Goals and Avoiding Harm

, 2022
Hypertonic saline has been used for the treatment of hyponatremia for nearly a century. There is now general consensus that hypertonic saline should be used in patients with hyponatremia associated with moderate or severe symptoms to prevent neurological
Sterns, Richard H, Rondon-Berrios, Helbert   +1 more
core   +1 more source

Comparing Effects of Intraventricular Hypertonic Saline and Magnesium Sulfate Application on Diffuse Brain Injury in Rats

, 2017
Objective: Diffuse brain injury is one of the most common issues encountered in, patients with trauma and it leads to morbidity and mortality via increased intracranial pressure.
iş, merih, Erhan Çelikoğlu, BİLGEN, SEVGİ, YILMAZ, BAYRAM, Taha Keleştemur, Özge Köner, Ayçiçek Çeçen, KÖNER, ÖZGE, Nurcan Kızılcık, çelikoğlu, erhan, Sevgi Bilgen, Merih İş, Bayram Yılmaz, Çeçen, Ayçiçek, KIZILCIK, NURCAN, KELEŞTEMUR, TAHA   +15 more
core   +1 more source