Results 11 to 20 of about 242,932 (222)

Hypertonic Saline or Carbocisteine in Bronchiectasis [PDF]

open access: yesNew England Journal of Medicine
Bronchiectasis guidelines are inconsistent with regard to the effectiveness of mucoactive agents, and their use varies geographically. Large trials are needed to assess safety and effectiveness.For this open-label, randomized, two-by-two factorial trial at 20 sites in the United Kingdom, we enrolled participants with non-cystic fibrosis bronchiectasis ...
Judy M. Bradley   +39 more
core   +11 more sources

Normal Saline Versus Hypertonic 3% Saline: It’s Efficacy in Non-Acute Rhinosinusitis [PDF]

open access: yesIranian Journal of Otorhinolaryngology, 2011
Introduction: Sinusitis is one of the most common diseases in general and in otolaryngology practice, but the optimal therapeutic options have not yet been fully developed. This manuscript will try to compare normal saline nasal douching with hypertonic
Nezamoddin Berjis   +4 more
doaj   +3 more sources

Hypertonic saline solution reduces the inflammatory response in endotoxemic rats [PDF]

open access: yesClinics, 2012
OBJECTIVE: Volume replacement in septic patients improves hemodynamic stability. This effect can reduce the inflammatory response. The objective of this study was to evaluate the effect of 7.5% hypertonic saline solution versus 0.9% normal saline ...
Mariana Cardillo Theobaldo   +4 more
doaj   +2 more sources

Effect of Hypertonic Saline during Flexible Nasopharyngeal Laryngoscopy: A Double-Blinded, Randomized, Controlled Trial

open access: yesJournal of Investigative Surgery, 2021
Objectives Flexible nasopharyngeal laryngoscopy (NPL) is a cost-effective, simple procedure that provides visualization of the nasal airways. However, it involves a number of challenges for both the clinician and the patient. Hypertonic saline nasal wash
Merih Onal   +4 more
doaj   +2 more sources

Hypertonic Saline in Treatment of Pulmonary Disease in Cystic Fibrosis [PDF]

open access: yesThe Scientific World Journal, 2012
The pathogenesis of lung disease in cystic fibrosis is characterised by decreased airway surface liquid volume and subsequent failure of normal mucociliary clearance.
Emer P. Reeves   +3 more
doaj   +2 more sources

Therapeutic effects of compound hypertonic saline on rats with sepsis [PDF]

open access: yesBrazilian Journal of Infectious Diseases, 2014
Sepsis is one of the major causes of death and is the biggest obstacle preventing improvement of the success rate in curing critical illnesses. Currently, isotonic solutions are used in fluid resuscitation technique.
Fang Dong   +4 more
doaj   +2 more sources

Hypertonic saline and reduced peroxynitrite formation in experimental pancreatitis [PDF]

open access: yesClinics, 2011
OBJECTIVES: In this study, we tested the hypothesis that hypertonic saline exerts anti-inflammatory effects by modulating hepatic oxidative stress in pancreatitis.
Ester Correia Sarmento Rios   +5 more
doaj   +2 more sources

Comparison of normal saline, hypertonic saline albumin and terlipressin plus hypertonic saline albumin in an infant animal model of hypovolemic shock. [PDF]

open access: yesPLoS ONE, 2015
In series of cases and animal models suffering hemorrhagic shock, the use of vasopressors has shown potential benefits regarding hemodynamics and tissue perfusion.
Javier Urbano   +8 more
doaj   +2 more sources

Painless intrathecal hypertonic saline [PDF]

open access: yesCanadian Anaesthetists’ Society Journal, 1974
Hypertonic saline, when injected into the lumbar subarachnoid space for the relief of intractable pain, causes pain, unpleasant muscle cramps and potentially dangerous sympathetic discharge. These side effects can be avoided by adding a weak concentration of local anaesthetic to the brine solution.
A W, Squire, O, Calvillo, P R, Bromage
openaire   +2 more sources

Efficacy and safety of hypertonic saline solutions fluid resuscitation on hypovolemic shock: A systematic review and meta-analysis of randomized controlled trials

open access: yesCardiology Journal, 2022
BACKGROUND: Fluid resuscitation is a fundamental intervention in patients with hypovolemic shock resulting from trauma. Appropriate fluid resuscitation in trauma patients could reduce organ failure, until blood components are available, and hemorrhage is
Kamil Safiejko   +7 more
doaj   +1 more source

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