The effects of hypertonic fluid administration on the gene expression of inflammatory mediators in circulating leucocytes in patients with septic shock: a preliminary study [PDF]
Contains fulltext : 98426.pdf (Publisher’s version ) (Open Access)ABSTRACT: OBJECTIVE: This study was designed to investigate the effect of hypertonic fluid administration on inflammatory mediator gene expression in patients with septic
James Sleigh +17 more
core +1 more source
Arginine or Hypertonic Saline-Stimulated Copeptin to Diagnose AVP Deficiency [PDF]
BACKGROUND Distinguishing between arginine vasopressin (AVP) deficiency and primary polydipsia is challenging. Hypertonic saline-stimulated copeptin has been used to diagnose AVP deficiency with high accuracy but requires close sodium monitoring ...
Soares, Beatriz S +20 more
core +3 more sources
Hypertonic Saline for Hyponatremia: Meeting Goals and Avoiding Harm
Hypertonic saline has been used for the treatment of hyponatremia for nearly a century. There is now general consensus that hypertonic saline should be used in patients with hyponatremia associated with moderate or severe symptoms to prevent neurological
Sterns, Richard H +1 more
core +1 more source
Hypertonic saline for fluid resuscitation in ICU patients post-cardiac surgery (HERACLES): a double-blind randomized controlled clinical trial. [PDF]
PURPOSE Recent evidence questions a liberal approach to fluid resuscitation in intensive care unit (ICU) patients. Here, we assess whether use of hypertonic saline applied as single infusion at ICU admission after cardiac surgery can reduce cumulative
Zuercher, Patrick +12 more
core +1 more source
The role for osmotic agents in children with acute encephalopathies: a systematic review
Background: Raised intracranial pressure (ICP) is known to complicate both traumatic and non-traumatic encephalopathies. It impairs cerebral perfusion and may cause death due to global ischaemia and intracranial herniation. Osmotic agents are widely used
Idro, R +14 more
core +1 more source
Objective: Diffuse brain injury is one of the most common issues encountered in, patients with trauma and it leads to morbidity and mortality via increased intracranial pressure.
iş, merih +15 more
core +1 more source
Hypertonic Saline in Treatment of Pulmonary Disease in Cystic Fibrosis [PDF]
The pathogenesis of lung disease in cystic fibrosis is characterised by decreased airway surface liquid volume and subsequent failure of normal mucociliary clearance.
Emer P. Reeves +3 more
core +1 more source
OBJECTIVE To compare the in vitro effects of hypertonic solutions and colloids to saline on coagulation in dogs. DESIGN In vitro experimental study. SETTING Veterinary teaching hospital.
Howard, J. +4 more
core +1 more source
Hypertonic saline in critical illness - A systematic review.
INTRODUCTION The optimal approach to fluid management in critically ill patients is highly debated. Fluid resuscitation using hypertonic saline was used in the past for more than thirty years, but has recently disappeared from clinical practice.
Pfortmüller, Carmen +3 more
core +1 more source
The interaction and pharmacological modulation of the cardiorespiratory responses to primary thoracic blast injury, haemorrhage resuscitation [PDF]
Blast injuries represent a problem for civilian and military populations. The response to thoracic blast injury involves a reflex bradycardia, hypotension and apnoea.
Sawdon, Mariana Annette +2 more
core

