Results 31 to 40 of about 125,918 (262)

Normal skin and hypertrophic scar fibroblasts differentially regulate collagen and fibronectin expression as well as mitochondrial membrane potential in response to basic fibroblast growth factor

open access: yesBrazilian Journal of Medical and Biological Research, 2011
Basic fibroblast growth factor (bFGF) regulates skin wound healing; however, the underlying mechanism remains to be defined. In the present study, we determined the effects of bFGF on the regulation of cell growth as well as collagen and fibronectin ...
Rui Song   +4 more
doaj   +1 more source

Evaluation of Scarring in Pediatrics Burns

open access: yesCentral Asian Journal of Medical Sciences, 2022
Objective: Post-burn hypertrophic scar occurs in between 30 - 90 % of burn patients and its most common risk factor is prolonged inflammation at the wound site.
Saranchimeg Enkhtuvshin   +3 more
doaj   +1 more source

Role of Topical Ritodrine Hydrochloride in Experimentally Induced Hypertrophic Scar in Rabbits

open access: yesIraqi Journal of Pharmaceutical Sciences, 2022
Hypertrophic scars are fibroproliferative illnesses caused by improper wound healing, during that, excessive inflammation, angiogenesis, and differentiated human dermal fibroblast (HDF ) function contribute to scarring, whereas hyperpigmentation ...
Haitham Kadhim   +3 more
doaj   +1 more source

The Use of Laser in Keloid and Hypertrophic Scar

open access: yes, 2023
Keloid and hypertrophic scar are hyperproliferation of dense connective tissue characterized by the growth of fibrotic tissue. The pathogenesis of keloid and hypertrophic scar is still expanding, hence there is no optimal therapy.
Sarah Diba   +4 more
core   +1 more source

The Long Non-Coding RNA LncRNA8975-1 is Upregulated in Hypertrophic Scar Fibroblasts and Controls Collagen Expression

open access: yesCellular Physiology and Biochemistry, 2016
Background/Aims: Long non-coding RNAs (lncRNAs) are thought to play crucial roles in human diseases. However, the function of lncRNAs in hypertrophic scar formation remains poorly understood.
Jun Li   +7 more
doaj   +1 more source

MicroRNA-182-5p Inhibits Hypertrophic Scar Formation by Inhibiting the Proliferation and Migration of Fibroblasts via SMAD4 Pathway

open access: yesClinical, Cosmetic and Investigational Dermatology, 2023
Mingzhu Jin,1 Xiao Xu2 1Department of Burns and Plastic Surgery, Fourth Medical Center of Chinese PLA General Hospital, Beijing, People’s Republic of China; 2Department of Ophthalmology, Third Medical Center of Chinese PLA General Hospital, Beijing ...
Jin M, Xu X
doaj  

Direct and Indirect Roles of Macrophages in Hypertrophic Scar Formation

open access: yesFrontiers in Physiology, 2019
Hypertrophic scars are pathological scars that result from abnormal responses to trauma, and could cause serious functional and cosmetic disability. To date, no optimal treatment method has been established.
Yi Feng   +15 more
doaj   +1 more source

Extracellular vesicles from Lactobacillus druckerii inhibit hypertrophic scar fibrosis

open access: yesJournal of Nanobiotechnology, 2023
Background Hypertrophic scars (HS) affect millions of people each year and require better treatment strategies. Bacterial extracellular vesicles (EVs) are advantaged by low cost and high yield which was commonly used in the treatment of diseases.
Fu Han   +6 more
doaj   +1 more source

ABT-263 Reduces Hypertrophic Scars by Targeting Apoptosis of Myofibroblasts

open access: yesFrontiers in Pharmacology, 2021
Background: Inhibiting proliferation and inducing apoptosis of myofibroblasts is becoming one of the promising and effective ways to treat hypertrophic scar.
Xiaolan Yang   +13 more
doaj   +1 more source

Macroscopic aspect of a hypertrophic scar in a nude mouse.

open access: yes, 2015
A. Characteristic stiffness of a human hypertrophic scars after 35 days. B. After sacrificing the animal, vessels can be seen coming from the surrounding tissue arrived to nourish the hypertrophic scar.
Bernardo Hontanilla (840627)   +2 more
core   +1 more source

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