Results 11 to 20 of about 674,192 (414)

MicroRNAs in Cardiac Hypertrophy [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
Like other organs, the heart undergoes normal adaptive remodeling, such as cardiac hypertrophy, with age. This remodeling, however, is intensified under stress and pathological conditions. Cardiac remodeling could be beneficial for a short period of time, to maintain a normal cardiac output in times of need; however, chronic cardiac hypertrophy may ...
Nadine Wehbe   +5 more
openaire   +3 more sources

Mechanisms of muscle atrophy and hypertrophy: implications in health and disease

open access: yesNature Communications, 2021
Skeletal muscle is the protein reservoir of our body and an important regulator of glucose and lipid homeostasis. Consequently, the growth or the loss of muscle mass can influence general metabolism, locomotion, eating and respiration.
R. Sartori, V. Romanello, M. Sandri
semanticscholar   +1 more source

Oxidative Stress as A Mechanism for Functional Alterations in Cardiac Hypertrophy and Heart Failure

open access: yesAntioxidants, 2021
Although heart failure due to a wide variety of pathological stimuli including myocardial infarction, pressure overload and volume overload is associated with cardiac hypertrophy, the exact reasons for the transition of cardiac hypertrophy to heart ...
A. Shah   +3 more
semanticscholar   +1 more source

NLRP3-mediated pyroptosis aggravates pressure overload-induced cardiac hypertrophy, fibrosis, and dysfunction in mice: cardioprotective role of irisin

open access: yesCell Death Discovery, 2021
The exact mechanism of myocardial hypertrophy has not been completely elucidated. NOD-like receptor protein 3 (NLRP3) and the pyroptotic cascade play a critical role in cardiac hypertrophy and inflammation. The myokine irisin can inhibit NLRP3 activation,
R. Yue   +9 more
semanticscholar   +1 more source

Hypertrophy of the gums [PDF]

open access: yesThe American Journal of the Medical Sciences, 1897
n ...
White, J. William   +2 more
openaire   +3 more sources

The Role of Chondrocyte Hypertrophy and Senescence in Osteoarthritis Initiation and Progression

open access: yesInternational Journal of Molecular Sciences, 2020
Osteoarthritis (OA) is the most common joint disease that causes pain and disability in the adult population. OA is primarily caused by trauma induced by an external force or by age-related cartilage damage.
Yeri Alice Rim, Yoojun Nam, J. Ju
semanticscholar   +1 more source

Macro, Micro, and Molecular. Changes of the Osteochondral Interface in Osteoarthritis Development

open access: yesFrontiers in Cell and Developmental Biology, 2021
Osteoarthritis (OA) is a long-term condition that causes joint pain and reduced movement. Notably, the same pathways governing cell growth, death, and differentiation during the growth and development of the body are also common drivers of OA.
Xiwei Fan   +6 more
doaj   +1 more source

Comparative Analysis of Muscle Hypertrophy Models Reveals Divergent Gene Transcription Profiles and Points to Translational Regulation of Muscle Growth through Increased mTOR Signaling

open access: yesFrontiers in Physiology, 2017
Skeletal muscle mass is a result of the balance between protein breakdown and protein synthesis. It has been shown that multiple conditions of muscle atrophy are characterized by the common regulation of a specific set of genes, termed atrogenes.
Marcelo G. Pereira   +16 more
doaj   +1 more source

Adaptations to Post-exercise Cold Water Immersion: Friend, Foe, or Futile?

open access: yesFrontiers in Sports and Active Living, 2021
In the last decade, cold water immersion (CWI) has emerged as one of the most popular post-exercise recovery strategies utilized amongst athletes during training and competition.
Mohammed Ihsan   +3 more
doaj   +1 more source

The Incidence and Clinical Relevance of Graft Hypertrophy After Matrix-Based Autologous Chondrocyte Implantation [PDF]

open access: yes, 2012
Background: Graft hypertrophy is the most common complication of periosteal autologous chondrocyte implantation (p-ACI). Purpose: The aim of this prospective study was to analyze the development, the incidence rate, and the persistence of graft ...
Annie Horng   +7 more
core   +1 more source

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