Results 21 to 30 of about 486,688 (369)

High-Throughput Precision Phenotyping of Left Ventricular Hypertrophy with Cardiovascular Deep Learning [PDF]

open access: yes, 2021
Left ventricular hypertrophy (LVH) results from chronic remodeling caused by a broad range of systemic and cardiovascular disease including hypertension, aortic stenosis, hypertrophic cardiomyopathy, and cardiac amyloidosis. Early detection and characterization of LVH can significantly impact patient care but is limited by under-recognition of ...
arxiv   +1 more source

The Role of Chondrocyte Hypertrophy and Senescence in Osteoarthritis Initiation and Progression

open access: yesInternational Journal of Molecular Sciences, 2020
Osteoarthritis (OA) is the most common joint disease that causes pain and disability in the adult population. OA is primarily caused by trauma induced by an external force or by age-related cartilage damage.
Yeri Alice Rim, Yoojun Nam, J. Ju
semanticscholar   +1 more source

Comparative Analysis of Muscle Hypertrophy Models Reveals Divergent Gene Transcription Profiles and Points to Translational Regulation of Muscle Growth through Increased mTOR Signaling

open access: yesFrontiers in Physiology, 2017
Skeletal muscle mass is a result of the balance between protein breakdown and protein synthesis. It has been shown that multiple conditions of muscle atrophy are characterized by the common regulation of a specific set of genes, termed atrogenes.
Marcelo G. Pereira   +16 more
doaj   +1 more source

Unilateral lateral mass hypertrophy: An extremely rare congenital anomaly of Atlas

open access: yesJournal of Craniovertebral Junction and Spine, 2013
A wide variety of congenital anomalies are observed around the craniovertebral junctional area. However, hypertrophied unilateral lateral mass of atlas in association with chiari-1 malformation leading to myelopathy is extremely uncommon.
Kuntal Kanti Das   +5 more
doaj   +1 more source

An Overview of Glycosylation and its Impact on Cardiovascular Health and Disease

open access: yesFrontiers in Molecular Biosciences, 2021
The cardiovascular system is a complex and well-organized system in which glycosylation plays a vital role. The heart and vascular wall cells are constituted by an array of specific receptors; most of them are N- glycosylated and mucin-type O ...
Karen Julissa Loaeza-Reyes   +11 more
doaj   +1 more source

Analysis of microRNA Expression Profiles Induced by Yiqifumai Injection in Rats with Chronic Heart Failure

open access: yesFrontiers in Physiology, 2018
Background: Yiqifumai Injection (YQFM) is clinically used to treat various cardiovascular diseases including chronic heart failure (CHF). The efficacy of YQFM for treating heart failure has been suggested, but the mechanism of action for pharmacological ...
Yu Zhao   +7 more
doaj   +1 more source

Case Report: Hepatic Artery Infusion Chemotherapy After Stage I ALPPS in a Patient With Huge HCC

open access: yesFrontiers in Surgery, 2021
Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) can induce rapid hypertrophy of the liver remnant. However, with a background of liver cirrhosis or other chronic liver diseases, patients with a huge hepatocellular ...
Wenfeng Zhuo   +5 more
doaj   +1 more source

Targeted Genetic Reduction of Mutant Huntingtin Lessens Cardiac Pathology in the BACHD Mouse Model of Huntington's Disease

open access: yesFrontiers in Cardiovascular Medicine, 2021
Individuals affected by Huntington's disease (HD) present with progressive degeneration that results in a wide range of symptoms, including cardiovascular (CV) dysfunction.
Saemi Park   +11 more
doaj   +1 more source

Intermittent hypoxia changes the interaction of the kinin–VEGF system and impairs myocardial angiogenesis in the hypertrophic heart

open access: yesPhysiological Reports, 2021
Intermittent hypoxia (IH) is a feature of obstructive sleep apnea (OSA), a condition highly associated with hypertension‐related cardiovascular diseases.
Bruna Visniauskas   +6 more
doaj   +1 more source

A circular RNA protects the heart from pathological hypertrophy and heart failure by targeting miR-223.

open access: yesEuropean Heart Journal, 2016
AIMS Sustained cardiac hypertrophy accompanied by maladaptive cardiac remodelling represents an early event in the clinical course leading to heart failure. Maladaptive hypertrophy is considered to be a therapeutic target for heart failure.
Kun Wang   +14 more
semanticscholar   +1 more source

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