FGF23 induces left ventricular hypertrophy.
Chronic kidney disease (CKD) is a public health epidemic that increases risk of death due to cardiovascular disease. Left ventricular hypertrophy (LVH) is an important mechanism of cardiovascular disease in individuals with CKD.
C. Faul+34 more
semanticscholar +1 more source
A potential biomarker of androgen exposure in European bullhead (Cottus sp.) kidney [PDF]
The aim of this study was to identify a signal that could be used as an androgen exposure indicator in the European bullhead (Cottus sp.). For this purpose, the ultra-structure of the kidney was characterized to identify normal structure of this organ, and histological changes previously described in the kidney of breeding male bullheads were ...
arxiv +1 more source
Computational Modeling of Cardiac Growth and Remodeling in Pressure Overloaded Hearts -- Linking Microstructure to Organ Phenotype [PDF]
Cardiac growth and remodeling (G&R) refers to structural changes in myocardial tissue in response to chronic alterations in loading conditions. One such condition is pressure overload where elevated wall stresses stimulate the growth in cardiomyocyte thickness, associated with a phenotype of concentric hypertrophy at the organ scale, and promote ...
arxiv +1 more source
Objective Consumption of pomegranate extract along with resistance training can improve the blood flow, resting metabolism and cause weight loss. However, their effect on body composition and weight control has not been studied.
Meysam Irani+2 more
doaj
Extracellular Vimentin Alters Energy Metabolism And Induces Adipocyte Hypertrophy [PDF]
Background Previous studies have reported that oxidative stress contributes to obesity characterized by adipocyte hypertrophy. However, mechanism has not been studied extensively. In the current study, we evaluated role of extracellular vimentin secreted
Ji-Hae Park, Soyeon Kwon, Young Mi Park
doaj +1 more source
Stimuli and sensors that initiate skeletal muscle hypertrophy following resistance exercise.
One of the most striking adaptations to exercise is the skeletal muscle hypertrophy that occurs in response to resistance exercise. A large body of work shows that a mammalian target of rapamycin complex 1 (mTORC1)-mediated increase of muscle protein ...
H. Wackerhage+4 more
semanticscholar +1 more source
: We investigated the expression of insulin-like growth factor 1 (IGF-1) and IGF-1 type 1 receptor (IGF-1R) in skeletal muscle fiber types in chickens with hepatic fibrosis induced by bile duct ligation (BDL).
J. Nagasao+11 more
doaj
Macro, Micro, and Molecular. Changes of the Osteochondral Interface in Osteoarthritis Development
Osteoarthritis (OA) is a long-term condition that causes joint pain and reduced movement. Notably, the same pathways governing cell growth, death, and differentiation during the growth and development of the body are also common drivers of OA.
Xiwei Fan+6 more
doaj +1 more source
Comorbid CAD and Ventricular Hypertrophy Compromise The Perfusion of Myocardial Tissue at Subcritical Stenosis of Epicardial Coronaries [PDF]
BACKGROUND: Most studies of CAD revascularization have been based on and reported according to angiographic criteria which don't consider the relation between the resulting effective flow distal to the stenosis and the demand of a hypertrophied myocardial tissue.
arxiv +1 more source
Self-supervised contrastive learning of echocardiogram videos enables label-efficient cardiac disease diagnosis [PDF]
Advances in self-supervised learning (SSL) have shown that self-supervised pretraining on medical imaging data can provide a strong initialization for downstream supervised classification and segmentation. Given the difficulty of obtaining expert labels for medical image recognition tasks, such an "in-domain" SSL initialization is often desirable due ...
arxiv +1 more source