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Exploring the mechanism underlying hyperuricemia using comprehensive research on multi-omics
Hyperuricemia involves multiple complex metabolisms, but no study has conducted a comprehensive analysis using human blood and urine metabolomics for hyperuricemia. Serum and urine samples from 10 patients with hyperuricemia and 5 controls were collected
Hengrui Liu+5 more
doaj +2 more sources
Background The prevalence of hyperuricemia, gout, and heart failure (HF) is on the rise, and these conditions often share similar risk factors. The present study aimed to evaluate the relationship among hyperuricemia, gout, HF, and all-cause mortality ...
Yingdong Han+7 more
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Association between organophosphate esters exposure and the prevalence of hyperuricemia in US adults from NHANES 2011–2016 [PDF]
Organophosphate esters (OPEs) exposure has potentially harmful effects on human health. However, the evidence between OPEs and hyperuricemia is insufficient. We aimed to assess the association between OPEs metabolites and the prevalence of hyperuricemia.
Qiong Huang+6 more
doaj +2 more sources
Associations of body mass index and remnant cholesterol with hyperuricemia in patients with hypertension [PDF]
Background There is a paucity of prior research on residual cholesterol (RC) and hyperuricemia, and it remains unclear whether body mass index (BMI) functions as a mediating factor between them or intensifies lipid metabolic dysregulation, thereby ...
Wei Zhou+6 more
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Lipid accumulation product: A novel marker for gout and hyperuricemia. [PDF]
Background and aimUsing cross-sectional data from the 2009-2018 National Health and Nutrition Examination Survey, the purpose of this study was to investigate the potential link between lipid accumulation product and gout/hyperuricemia.MethodsThe data ...
Dexian Xian+9 more
doaj +2 more sources
Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and hyperuricemia: evidence from the CHARLS study [PDF]
Background and aimsThe non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) is an innovative composite lipid measure.
Xin Hou+8 more
doaj +2 more sources
Association between hyperuricemia and all-cause mortality in people taken Statins: a retrospective cohort study [PDF]
BackgroundStatins are one of the most widely prescribed medicines in clinical practice. Their benefits have extended beyond cardiovascular applications to reduce serum uric acid levels.
Bin Zhu+6 more
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Circular RNAs (circRNAs) are non-coding RNAs (ncRNAs) with a single-stranded covalently closed-loop structure, and their abnormal expression may participate in the pathogenesis of various human diseases.
Fei Dai+11 more
doaj +1 more source
Introduction: MicroRNA-223 (MiR-223) serves as an important regulator of inflammatory and immune responses and is implicated in several auto-inflammatory disorders.
Quan-Bo Zhang+18 more
doaj +1 more source
Uric acid (UA) is synthesized mainly in the liver, intestines, and vascular endothelium as the end product of an exogenous purine from food and endogenously from damaged, dying, and dead cells.
H. Yanai+3 more
semanticscholar +1 more source