Results 11 to 20 of about 70,452 (325)

Exploring the mechanism underlying hyperuricemia using comprehensive research on multi-omics

open access: yesScientific Reports, 2023
Hyperuricemia involves multiple complex metabolisms, but no study has conducted a comprehensive analysis using human blood and urine metabolomics for hyperuricemia. Serum and urine samples from 10 patients with hyperuricemia and 5 controls were collected
Hengrui Liu   +5 more
doaj   +2 more sources

Hyperuricemia and gout increased the risk of long-term mortality in patients with heart failure: insights from the National Health and Nutrition Examination Survey

open access: yesJournal of Translational Medicine, 2023
Background The prevalence of hyperuricemia, gout, and heart failure (HF) is on the rise, and these conditions often share similar risk factors. The present study aimed to evaluate the relationship among hyperuricemia, gout, HF, and all-cause mortality ...
Yingdong Han   +7 more
doaj   +2 more sources

Association between organophosphate esters exposure and the prevalence of hyperuricemia in US adults from NHANES 2011–2016 [PDF]

open access: yesScientific Reports
Organophosphate esters (OPEs) exposure has potentially harmful effects on human health. However, the evidence between OPEs and hyperuricemia is insufficient. We aimed to assess the association between OPEs metabolites and the prevalence of hyperuricemia.
Qiong Huang   +6 more
doaj   +2 more sources

Associations of body mass index and remnant cholesterol with hyperuricemia in patients with hypertension [PDF]

open access: yesBMC Endocrine Disorders
Background There is a paucity of prior research on residual cholesterol (RC) and hyperuricemia, and it remains unclear whether body mass index (BMI) functions as a mediating factor between them or intensifies lipid metabolic dysregulation, thereby ...
Wei Zhou   +6 more
doaj   +2 more sources

Lipid accumulation product: A novel marker for gout and hyperuricemia. [PDF]

open access: yesPLoS ONE
Background and aimUsing cross-sectional data from the 2009-2018 National Health and Nutrition Examination Survey, the purpose of this study was to investigate the potential link between lipid accumulation product and gout/hyperuricemia.MethodsThe data ...
Dexian Xian   +9 more
doaj   +2 more sources

Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and hyperuricemia: evidence from the CHARLS study [PDF]

open access: yesFrontiers in Nutrition
Background and aimsThe non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) is an innovative composite lipid measure.
Xin Hou   +8 more
doaj   +2 more sources

Association between hyperuricemia and all-cause mortality in people taken Statins: a retrospective cohort study [PDF]

open access: yesFrontiers in Pharmacology
BackgroundStatins are one of the most widely prescribed medicines in clinical practice. Their benefits have extended beyond cardiovascular applications to reduce serum uric acid levels.
Bin Zhu   +6 more
doaj   +2 more sources

Expression Profile and Potential Function of Circular RNAs in Peripheral Blood Mononuclear Cells in Male Patients With Primary Gout

open access: yesFrontiers in Genetics, 2021
Circular RNAs (circRNAs) are non-coding RNAs (ncRNAs) with a single-stranded covalently closed-loop structure, and their abnormal expression may participate in the pathogenesis of various human diseases.
Fei Dai   +11 more
doaj   +1 more source

MicroRNA-223 Suppresses IL-1β and TNF-α Production in Gouty Inflammation by Targeting the NLRP3 Inflammasome

open access: yesFrontiers in Pharmacology, 2021
Introduction: MicroRNA-223 (MiR-223) serves as an important regulator of inflammatory and immune responses and is implicated in several auto-inflammatory disorders.
Quan-Bo Zhang   +18 more
doaj   +1 more source

Molecular Biological and Clinical Understanding of the Pathophysiology and Treatments of Hyperuricemia and Its Association with Metabolic Syndrome, Cardiovascular Diseases and Chronic Kidney Disease

open access: yesInternational Journal of Molecular Sciences, 2021
Uric acid (UA) is synthesized mainly in the liver, intestines, and vascular endothelium as the end product of an exogenous purine from food and endogenously from damaged, dying, and dead cells.
H. Yanai   +3 more
semanticscholar   +1 more source

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