Results 11 to 20 of about 57,118 (288)

The effect of body weight and alcohol consumption on hyperuricemia and their attributable population fractions: A National health survey in China

Obesity Facts, 2021
Introduction: The prevalence of hyperuricemia is increasing world widely; the understanding of population attributable faction of modifiable risk factors is important for disease prevention.
Huijing He, Li Pan, Xiaolan Ren, Dingming Wang, Jianwei Du, Ze Cui, Jingbo Zhao, Hailing Wang, Xianghua Wang, Feng Liu, Lize Pa, Xia Peng, Ye Wang, Chengdong Yu, Guangliang Shan   +14 more
doaj   +1 more source

Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney. [PDF]

, 2016
BackgroundExcess body burden of uric acid promotes gout. Diminished renal clearance of uric acid causes hyperuricemia in most patients with gout, and the renal urate transporter (URAT)1 is important for regulation of serum uric acid (sUA) levels.
Girardet, Jean-Luc, Hagerty, David T, Hyndman, David, Iverson, Cory, Liu, Sha, Manhard, Kimberly, Miner, Jeffrey N, Nanavati, Payal, Quart, Barry, Shen, Zancong, Tan, Philip K, Terkeltaub, Robert, Yeh, Li-Tain   +12 more
core   +2 more sources

Effect of Asymptomatic Hyperuricemia on Mortality of Elderly Patients After Elective Percutaneous Coronary Intervention

Frontiers in Cardiovascular Medicine, 2022
PurposeThe purpose of this study is to investigate the effect of asymptomatic hyperuricemia on mortality of elderly patients with coronary artery disease (CAD) after elective percutaneous coronary intervention (PCI).MethodsOne thousand two hundred ninety-
Chen Chen, Jianzeng Dong, Qiang Lv, Xinmin Liu, Qian Zhang, Xin Du   +5 more
doaj   +1 more source

Serum uric acid as a marker of microvascular damage in systemic sclerosis patients [PDF]

, 2016
Background: Microvascular damage of skin and internal organs is a hallmark of systemic sclerosis (SSc). Serum uric acid (UA) represents a marker of inflammation and endothelial dysfunction.
Amoroso, Antonio, Barbano, Biagio, Barilaro, Giuseppe, Cianci, Rosario, Di Mario, Francesca, Gasperini, Maria Ludovica, Gigante, Antonietta, Quarta, Silvia, Romaniello, Antonella, Rosato, Edoardo   +9 more
core   +1 more source

Antiepileptic drugs reduce serum uric acid [PDF]

, 1987
Uric acid examination in 554 epileptic out-patients under long-term anticonvulsant medication revealed significantly lower serum concentrations compared to a group of normal controls.
Arab, Bernhard Schellenberg, Heinrich Schmidt-Gayk, Klaus-Henning Krause, Meinardi, Peter Berlit, Richens, Yeung   +7 more
core   +1 more source

Uric acid is more strongly associated with impaired glucose regulation in women than in men from the general population: the KORA F4-Study. [PDF]

, 2012
High serum uric acid (UA) levels are associated with the metabolic syndrome, type 2 diabetes and cardiovascular disease. It is largely unknown whether there are gender-specific differences regarding the association between UA and prediabetic states.
Döring, Angela, Kowall, Bernd, Meisinger, Christa, Rathmann, Wolfgang, Stöckl, Doris, Thorand, Barbara   +5 more
core   +10 more sources

The role of urate and xanthine oxidase in vascular oxidative stress:Future directions [PDF]

, 2009
Vascular oxidative stress has been shown to be a potent factor in the pathophysiology of endothelial dysfunction. Despite current optimal evidence-based therapy, mortality from various cardiovascular disorders remains high.
George, Jacob, Struthers, Allan
core   +5 more sources

Influence of occupational exposure on hyperuricemia in steelworkers: a nested case–control study

BMC Public Health, 2022
Background Occupational exposure may be associated with an increased risk of developing hyperuricemia. This study sheds lights on the association between occupational exposure and hyperuricemia in steelworkers.
Yuanyu Chen, Yongzhong Yang, Ziwei Zheng, Hui Wang, Xuelin Wang, Zhikang Si, Rui Meng, Guoli Wang, Jianhui Wu   +8 more
doaj   +1 more source

Linear and non-linear Mendelian randomization analyses of sex-specific associations between sleep duration and hyperuricemia

Frontiers in Nutrition, 2022
BackgroundObservational studies have suggested a potential non-linear association between sleep duration and hyperuricemia. However, the causal nature and sex-specific differences are poorly understood.
Chenfeng Zou, Zhenqian Wang, Wenyu Huang, Jiawen Lu, Vivian Yawei Guo, Yuying Zhang, Shufei Zang, Jinying Yang, Liyuan Han, Guozhi Jiang   +9 more
doaj   +1 more source

What makes gouty inflammation so variable? [PDF]

, 2017
Acute gout arthritis flares contribute dominantly to gout-specific impaired health-related quality of life, representing a progressively increasing public health problem.
Terkeltaub, Robert
core   +2 more sources