Results 41 to 50 of about 70,452 (325)

Serum uric acid as a marker of microvascular damage in systemic sclerosis patients [PDF]

, 2016
Background: Microvascular damage of skin and internal organs is a hallmark of systemic sclerosis (SSc). Serum uric acid (UA) represents a marker of inflammation and endothelial dysfunction.
Amoroso, Antonio, Barbano, Biagio, Barilaro, Giuseppe, Cianci, Rosario, Di Mario, Francesca, Gasperini, Maria Ludovica, Gigante, Antonietta, Quarta, Silvia, Romaniello, Antonella, Rosato, Edoardo   +9 more
core   +1 more source

The Role of Oxidative Stress in Hyperuricemia and Xanthine Oxidoreductase (XOR) Inhibitors

Oxidative Medicine and Cellular Longevity, 2021
Uric acid is the end product of purine metabolism in humans. Hyperuricemia is a metabolic disease caused by the increased formation or reduced excretion of serum uric acid (SUA).
Ning Liu, Hu Xu, Qianqian Sun, Xiaojuan Yu, Wentong Chen, Hongquan Wei, Jie Jiang, Youzhi Xu, Wenjie Lu   +8 more
semanticscholar   +1 more source

Limosilactobacillus fermentum JL-3 isolated from “Jiangshui” ameliorates hyperuricemia by degrading uric acid

Gut microbes, 2021
Recent studies into the beneficial effects of fermented foods have shown that this class of foods are effective in managing hyperuricemia and gout.
Ying Wu, Ze Ye, P. Feng, Rong Li, Xiao Chen, Xiao-zhu Tian, Rong Han, Apurva Kakade, Pu Liu, Xiangkai Li   +9 more
semanticscholar   +1 more source

Association between nutrient patterns and hyperuricemia: mediation analysis involving obesity indicators in the NHANES

BMC Public Health, 2022
Diet has long been hypothesized to play an important role in hyperuricemia, and weight gain is a factor that is strongly associated with the rise in serum urate.
Juping Wang, Shuting Chen, Junkang Zhao, Jie Liang, Xue Gao, Q. Gao, Simin He, Tong Wang   +7 more
semanticscholar   +1 more source

Does obesity modify the epidemiological association between hyperuricemia and the prevalence of hypertension among Northern Chinese community-dwelling people? A Chinese population-based study

BMJ Open, 2019
Objectives Hyperuricemia and obesity both play a role in the development of hypertension. However, limited evidence is available for the combined effect of hyperuricemia and obesity on the prevalence of hypertension in the Chinese population. We aimed to
Simiao Tian, Yazhuo Liu, Ao Feng, Yang Xu   +3 more
doaj   +1 more source

Contemporary Prevalence of Gout and Hyperuricemia in the United States and Decadal Trends: The National Health and Nutrition Examination Survey, 2007–2016

Arthritis & Rheumatology, 2019
To estimate the current prevalence rates and decadal trends of gout and hyperuricemia in the US, as well as the prevalence of urate‐lowering therapy (ULT) among gout patients, using 2007–2016 data from a nationally representative survey of American men ...
M. Chen-Xu, C. Yokose, S. Rai, M. Pillinger, Hyon K. Choi   +4 more
semanticscholar   +1 more source

Effect of Asymptomatic Hyperuricemia on Mortality of Elderly Patients After Elective Percutaneous Coronary Intervention

Frontiers in Cardiovascular Medicine, 2022
PurposeThe purpose of this study is to investigate the effect of asymptomatic hyperuricemia on mortality of elderly patients with coronary artery disease (CAD) after elective percutaneous coronary intervention (PCI).MethodsOne thousand two hundred ninety-
Chen Chen, Jianzeng Dong, Qiang Lv, Xinmin Liu, Qian Zhang, Xin Du   +5 more
doaj   +1 more source

Uric acid is more strongly associated with impaired glucose regulation in women than in men from the general population: the KORA F4-Study. [PDF]

, 2012
High serum uric acid (UA) levels are associated with the metabolic syndrome, type 2 diabetes and cardiovascular disease. It is largely unknown whether there are gender-specific differences regarding the association between UA and prediabetic states.
Döring, Angela, Kowall, Bernd, Meisinger, Christa, Rathmann, Wolfgang, Stöckl, Doris, Thorand, Barbara   +5 more
core   +4 more sources

Obesity-Related Genetic Variants and Hyperuricemia Risk in Chinese Men

Frontiers in Endocrinology, 2019
Objective: Obesity/metabolic syndrome and hyperuricemia are clinically associated; however, the association of obesity/metabolic syndrome-related genetic variants with hyperuricemia is not clear.
Zhimin Ma, Yunfeng Wang, Yunfeng Wang, Chaonan Xu, Chaonan Xu, Feiling Ai, Feiling Ai, Ling Huang, Jieping Wang, Ji Peng, Yanming Zhou, Yanming Zhou, Meihua Yin, Meihua Yin, Shan Zhang, Shan Zhang, Xinghua Yang, Xinghua Yang   +17 more
doaj   +1 more source

Engineered Escherichia coli Nissle 1917 with urate oxidase and an oxygen-recycling system for hyperuricemia treatment

Gut microbes, 2022
Hyperuricemia is the second most prevalent metabolic disease to human health after diabetes. Only a few clinical drugs are available, and most of them have serious side effects.
R. Zhao, Zimai Li, Yuqing Sun, Wei Ge, Mingyu Wang, Huaiwei Liu, Luying Xun, Yongzhen Xia   +7 more
semanticscholar   +1 more source