Results 81 to 90 of about 57,118 (288)

Cardiometabolic‐Inflammatory Risk Factors and Cognitive Decline Among Older Indians—Report From a Nationally Representative, Longitudinal Study

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Rapid increase in cardiometabolic diseases in India may contribute to increased incidence of late‐life cognitive impairment. This study focuses on associations between baseline cardiometabolic risk factors and subsequent decline in cognitive function among older adults in India, leveraging data from two waves (Wave 1: 2017–2020 ...
Joyita Banerjee, Jung Ki Kim, Emma Nichols, Pranali Khobragade, A. B. Dey, Sharmistha Dey, Eileen Crimmins, David Flood, Kenneth M. Langa, Jinkook Lee, Peifeng Hu   +10 more
wiley   +1 more source

Exogenous chemical exposures and metabolic disruptions in hyperuricemia: a multi-omics mediation study

Environment International
Background: Hyperuricemia has emerged as a significant public health concern. However, the relationship between hyperuricemia and both individual and mixed exogenous chemicals remains poorly understood, and the underlying mechanisms are still unclear ...
Yang Ouyang, Lvyun Sun, Di Yu, Qi Li, Shanshan Du, Xiaolin Wang, Mengyao Wang, Guowang Xu, Weimin Ye, Xinyu Liu   +9 more
doaj   +1 more source

Convergent Evolution and De Novo Reconstitution of Apiin Biosynthesis

Plant Biotechnology Journal, EarlyView.
ABSTRACT Apiin, an active flavonoid apioside, occurs in phylogenetically distant plants, such as parsley and chilli pepper (Capsicum annuum L.). Its sporadic distribution suggests the existence of convergent apiin biosynthesis; however, the molecular mechanisms underlying this convergence remain unclear.
Zhen Xu, Zheng‐Shuang Zhu, Hai‐Zhu Jia, Jian‐Qiang Kong   +3 more
wiley   +1 more source

An inverted J-shaped association of serum uric acid with muscle strength among Japanese adult men: a cross-sectional study [PDF]

, 2013
BACKGROUND: Uric acid (UA) may protect muscle function from oxidative damage due to reactive oxygen species through its powerful antioxidant capacity.
Atsushi Otomo, Cong Huang, Haruki Momma, Hiroko Tadaura, Hui Guo, Kaijun Niu, Lei Guan, Masahiro Chujo, Ryoichi Nagatomi, Yoritoshi Kobayashi, Yufei Cui   +10 more
core   +1 more source

A case of hemobilia caused by a pseudoaneurysm resulting in obstructive cholangitis in a patient who underwent plastic stent placement for pancreatic cancer (with video)

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Hemobilia, or hemorrhage within the biliary system, is an uncommon cause of stent obstruction associated with bile duct strictures that are rarely observed with plastic stents. Reports of a pseudoaneurysm as a cause of hemobilia after plastic stent placement are also rare.
Yusuke Seyama, Akinori Sugaya, Ken Koyama, Hiroyuki Honda, Hajime Ishibashi, Masaharu Yamaoka, Mitsuharu Ozeki, Mitsuhide Goto, Masahiro Araki, Kenji Amagai   +9 more
wiley   +1 more source

Association between organophosphate esters exposure and the prevalence of hyperuricemia in US adults from NHANES 2011–2016

Scientific Reports
Organophosphate esters (OPEs) exposure has potentially harmful effects on human health. However, the evidence between OPEs and hyperuricemia is insufficient. We aimed to assess the association between OPEs metabolites and the prevalence of hyperuricemia.
Qiong Huang, Wenbin Nan, Siqi Li, Baimei He, Xu Cai, Zhenyu Peng, Chenlu Wu   +6 more
doaj   +1 more source

A case of duodenal pyloric gland adenoma with high‐grade dysplasia arising from ectopic gastric mucosa

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Superficial non‐ampullary duodenal epithelial tumor is a rare disease, but its frequency has reportedly been increasing in recent years. We report a case of duodenal pyloric gland adenoma with high‐grade dysplasia arising from ectopic gastric mucosa.
Kenichiro Nakachi, Hironobu Nagumo, Tetsuro Okura, Wataru Ohno, Takashi Ashikawa, Tomoyuki Funato, Toshiyasu Shiratori, So Nakaji, Shion Ando   +8 more
wiley   +1 more source

Taurine alleviates dysfunction of cholesterol metabolism under hyperuricemia by inhibiting A2AR-SREBP-2/CREB/HMGCR axis

Journal of Lipid Research
Dysfunctional cholesterol metabolism is highly prevalent in patients with hyperuricemia. Both uric acid and cholesterol are independent risk factors for atherosclerosis, contributing to an increased incidence of cardiovascular disease in hyperuricemia ...
Beibei Chen, Ruixia Bao, Jujie Pan, Zicheng Zhu, Qian Chen, Dan Wang, Yuzheng Wu, Haiyang Yu, Yi Zhang, Tao Wang   +9 more
doaj   +1 more source

Gouty Tophi of the Fingertips Induced by Repeated Microtrauma

JEADV Clinical Practice, EarlyView.
A. Gotor‐Rivera, R. F. Matilla‐Naumionek, J. L. Rodríguez‐Peralto, B. González Rodríguez   +3 more
wiley   +1 more source

Association of baseline characteristics with clinical outcomes of tirzepatide treatment in Japanese patients with obesity disease: A subgroup analysis of the SURMOUNT‐J trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1278-1287, February 2026.
Abstract Aims This analysis aimed to assess the influence of selected baseline factors on tirzepatide treatment response in Japanese patients with obesity disease. Materials and Methods This was a prespecified subgroup analysis of the SURMOUNT‐J trial.
Koutaro Yokote, Yasushi Fukushima, Tomotaka Shingaki, Tomonori Oura, Wataru Ogawa   +4 more
wiley   +1 more source