Results 41 to 50 of about 14,051 (235)

Pharmacological evaluation and preclinical studies of hypochlorous acid solution

Ukrainian Journal of Veterinary and Agricultural Sciences, 2023
The article presents materials on the electrochemical synthesis of hypochlorous acid and its pharmacological and toxicological evaluation. In the market of veterinary drugs, special attention has been paid to long-known, potent detoxifying antimicrobial ...
O. M. Brezvyn, I. Ya. Kotsiumbas, O. B. Velichenko, O. B. Shmychkova, T. V. Luk'yanenko, D. V. Girenko, L. V. Dmitrikova   +6 more
doaj   +1 more source

Hypochlorous acid inactivates oral pathogens and a SARS-CoV-2-surrogate

BMC Oral Health, 2023
Background Droplets and aerosols produced during dental procedures are a risk factor for microbial and viral transmission. Unlike sodium hypochlorite, hypochlorous acid (HOCl) is nontoxic to tissues but still exhibits broad microbicidal effect.
Kento Tazawa, Rutuja Jadhav, Mariane Maffei Azuma, J. Christopher Fenno, Neville J. McDonald, Hajime Sasaki   +5 more
doaj   +1 more source

Durable Physically Mixed Microporous and Mesoporous MOFs/Nanofiber Aerogel 3D Composites for Effective Toxic Gas Capture and Organophosphonate Detoxification

Advanced Functional Materials, EarlyView.
Ultralight 3D nanofibrous aerogels embedded with metal‐organic frameworks effectively capture and neutralize toxic gases and organophosphonates. Incorporating mesoporous UiO‐66‐NH2 and HKUST‐1 into PAN/PVP fibers enables high MOF loading while maintaining mechanical strength and structural stability.
Mai O. Abdelmigeed, Muhammed Ziauddin Ahmad Ebrahim, John J. Mahle, Brandon B. Blount, Gregory W. Peterson, Saad A. Khan, Gregory N. Parsons   +6 more
wiley   +1 more source

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

Antimicrobial Efficacy of a Taurolidine‐Based Antimicrobial Compound on Contaminated Surfaces Simulated in a Standardized 4‐Field Test

Advanced Healthcare Materials, EarlyView.
As implantable medical devices become indispensable to modern medicine, a silent threat grows alongside them: device‐associated infections. Despite decades of antibiotic innovation, infection rates keep climbing, costing lives and billions in healthcare expenses.
Benito Baldauf, Hendrik Bonnemeier, Ernest W. Lau, Jana Hummel, Reinhard Vonthein, Ojan Assadian   +5 more
wiley   +1 more source

Air purification by hypochlorous acid gas [PDF]

Journal of Hygiene, 1941
1. A short synopsis of research upon application of hypochlorites to airpurification is given.2. A short review of the most recent work on this subject shows that:(a) Of the “nebulizers” employed by Baker, Finn & Twort (1940) the “Atmozon” is incapable of consistent atomizing of hypochlorites, whilst the “Aerograph” has an efficiency much below ...
openaire   +2 more sources

Fragmentation of extracellular matrix by hypochlorous acid [PDF]

Biochemical Journal, 2003
The interaction of extracellular matrix with cells regulates their adhesion, migration and proliferation, and it is believed that damage to vascular matrix components is a factor in the development of atherosclerosis. Evidence has been provided for a role for the haem enzyme MPO (myeloperoxidase), released by activated monocytes (and possibly ...
Woods, Alan A, Davies, Michael Jonathan
openaire   +3 more sources

Oxygen and ROS Delivery for Infected Wound Healing and Future Prospects

Advanced Healthcare Materials, EarlyView.
Bacterial infection is a major driver of delayed wound healing and postsurgical readmissions; with rising antibiotic resistance, solid peroxide–releasing biomaterials offer sustained delivery of ROS/O2 for antimicrobial control and microenvironmental modulation.
Ayden Watt, Chably Rachella, Charlotte Jaloux, Joshua Vorstenbosch, Adam Hart, Michael Tanzer, Geraldine Merle, Jake Barralet   +7 more
wiley   +1 more source

Programmable Pentamolecular Cross‐Scale Imaging Reveals the Multiplicative Synergistic Effect of High‐Fat / High‐Salt Diet on Atherosclerosis

Advanced Science, EarlyView.
This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li, Na Zhao, Mengmeng Lu, Ruize Zhao, Wei Zhang, Ping Li, Yue Tang, Wen Zhang, Hui Wang, Bo Tang   +9 more
wiley   +1 more source

A fluorescence probe for monitoring toxic hypochlorous acid in biosystems and environmental waters with a broad pH adaptation

Ecotoxicology and Environmental Safety
Hypochlorous acid (HOCl) is commonly utilized in various daily applications. As a toxic reactive oxygen species (ROS) that generated from the industrial and pharmaceutical aspects, it plays a critical role in the mass cycle of environmental system and ...
Junyan Ma, Zilin Jiao, Mingtao Zhao, Xiangtao Kong, Hua Xie, Zhenxing Zhang   +5 more
doaj   +1 more source