This dissertation addresses the applications of ultrafast laser spectroscopy in investigating the photophysical properties of hypericin, hypocrellin and their analogs, as well as the structure of protein.;Hypericin and hypocrellin are naturally occurring
Wen, Jin
core +1 more source
Hypericin, a naturally occurring polycyclic quinone in the flower, St. John's Wort, has been shown to inactivate retroviruses such as Equine Infectious Anemia Virus (EIAV) and Human Immunodeficiency Virus (HIV). This inactivation has been shown to depend
Fehr, Michael
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Artificial intelligence driven workflow for accelerating design of novel photosensitizers
The discovery of high-performance photosensitizers has long been hindered by the time-consuming and resource-intensive nature of traditional trial-and-error approaches.
Hongyi Wang +4 more
doaj +1 more source
Effect of Chelation to Lanthanum Ions on the Photodynamic Properties of Hypocrellin A
Hypocrellin A (HA), an efficient phototherapeutic agent, can chelate with lanthanum ion to form a 1:1 complex, which exhibits enhanced 1O2 generation quantum yield, a red-shifted absorption window, greatly improved water solubility, a much lengthened ...
Shengqin Xia (2496502) +4 more
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Exploring Ground-State Heterogeneity of Hypericin and Hypocrellin A and B: Dynamic and 2D ROESY NMR Study [PDF]
A NMR study was conducted on the antiviral and antitumor agents hypericin and hypocrellin A and B, whose activity is light induced. Elucidation of the conformational/tautomeric properties of these polycyclic quinones is important for interpreting their ...
Petrich, Jacob +3 more
core
Advances and perspectives on perylenequinone biosynthesis. [PDF]
Deng H +5 more
europepmc +1 more source
Artificial Intelligence and Natural Photosensitizer-Based Nanopharmaceuticals in Photodynamic Therapy: Advanced Modeling, Data-Driven Optimization, and Translational Perspectives. [PDF]
Gonçalves RS, Costa EV.
europepmc +1 more source
This data is the supplemental material for the manuscript, Caged-hypocrellin mediated antimicrobial photodynamic therapy as a dual-action strategy for fungal clearance and immune response regulation in drug-resistant Candida auris wound ...
Ran, Yuping
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Endothelial soluble guanylate cyclase enzyme inhibitors as a novel target for the treatment of sepsis-related hypotension. [PDF]
Suleiman YAA, Khalil AMM, Almofti YA.
europepmc +1 more source
Polymer-Based Nanomaterials for Pharmaceutical, Biomedical and Environmental Applications-New Trends, Benefits and Future Opportunities. [PDF]
Rydz J +2 more
europepmc +1 more source

