Enhancing the Photosensitivity of Hypocrellin A by Perylene Diimide Metallacage-Based Host–Guest Complexation for Photodynamic Therapy [PDF]
Nano-Micro LettersHighlights A new type of metallacage was successfully fabricated and used as containers for hypocrellin-type photosensitizers, which prevented the self-aggregation of photosensitizers in aqueous solution.
Rongrong Li +9 more
doaj +3 more sources
Hypocrellin-Mediated PDT: A Systematic Review of Its Efficacy, Applications, and Outcomes [PDF]
International Journal of Molecular SciencesPhotodynamic therapy (PDT) is a light-activated treatment that generates reactive oxygen species (ROS) to induce microbial cell death. As resistance to traditional antibiotics intensifies globally, PDT has emerged as a promising alternative or adjunctive
Rafał Wiench +2 more
exaly +3 more sources
Rubroshiraia gen. nov., a second hypocrellin-producing genus in Shiraiaceae (Pleosporales) [PDF]
MycoKeys, 2019 Shiraiaceae is an important family in Pleosporales (Dothideomycetes), which includes medical fungi and plant pathogens. Two hypocrellin-producing taxa, Shiraia bambusicola and a novel genus Rubroshiraia gen.
Dong-Qin Dai +13 more
doaj +5 more sources
LED Light-Activated Hypocrellin B Induces Mitochondrial Damage of Ovarian Cancer Cells
International Journal of Photoenergy, 2012 Objective. Hypocrellin is a natural photosensitizer from a traditional Chinese herb. In the present study, our aim is to investigate the effect of LED light-activated hypocrellin B on mitochondria of ovarian cancer cells. Material and Methods.
Yuan Jiang +3 more
doaj +2 more sources
Fermentation, 2021 Hypocrellin is a natural 3,10-xylene-4,9-anthracene derivative compound that originates from the stroma of Shiraia bambusicola (S. bambusicola) and Hypocrella bambusae with excellent photobiological activities.
Xiaoxiao Yan +4 more
doaj +2 more sources
Effect of Light-Activated Hypocrellin B on the Growth and Membrane Permeability of Gram-Negative Escherichia coli Cells [PDF]
International Journal of Photoenergy, 2014 Aim. To investigate the effect of light-activated hypocrellin B on the growth and membrane permeability of Gram-negative bacteria. Methods. Escherichia coli (E.
Yuan Jiang +4 more
doaj +2 more sources
Drug-delivery and multifunction possibilities of hypocrellin photosensitizers [PDF]
Journal of Innovative Optical Health Sciences, 2015 Photodynamic therapy (PDT) has been a routine treatment of tumors and some microvascular diseases, but clinically available photosensitizers are still scarce.
Hong Deng, Jie Xie, Jingquan Zhao
doaj +2 more sources
Natural Product-Based Upconversion–Downshifting Photosensitizers in Photodynamic Therapy [PDF]
PharmaceuticalsNatural product-based upconversion photosensitizers (PSs) have emerged as innovative agents in photodynamic therapy (PDT). Lanthanide ions such as Yb3+, Er3+, Nd3+, Gd3+, and Tm3+ have unique photophysical properties and biocompatibility, exhibiting ...
Xiaohui Li +4 more
doaj +2 more sources
Hypocrellin: A Natural Photosensitizer and Nano-Formulation for Enhanced Molecular Targeting of PDT of Melanoma. [PDF]
Wiley Interdiscip Rev Nanomed NanobiotechnolNanotechnology and combination with natural photosensitizers are a prospective means of controlling cancer. Studies on photodynamic therapy (PDT) have shown that improvements in drug administration are required in order to preserve or enhance the mechanistic cell killing effects of PDT on malignant cells.
Gugu Nkosi PW, Chandran R, Abrahamse H.
europepmc +2 more sources
Biotechnology & Biotechnological Equipment, 2016 Hypocrellins is regarded as the new generation of potential photosensitizer in the photodynamic therapy. However, the current production of HA in large quantity is limited, whether extracted from the fruit bodies of Hypcrella bambusae and Shiraia ...
Xiao-Ye Shen +3 more
doaj +2 more sources