Enhanced hypocrellin production of Shiraia sp. SUPER-H168 by overexpression of alpha-amylase gene. [PDF]
PLoS ONE, 2018 Relative expression levels of twenty-four amylase genes in Shiraia sp. SUPER-H168 were investigated by real-time quantitative PCR when various carbohydrates, including glucose, sucrose, maltose, amylose, amylopectin and corn flour, were used as carbon ...
Ruijie Gao +7 more
doaj +2 more sources
Polyphenolic natural products as photosensitizers for antimicrobial photodynamic therapy: recent advances and future prospects [PDF]
Frontiers in Immunology, 2023 Antimicrobial photodynamic therapy (aPDT) has become a potent contender in the fight against microbial infections, especially in the context of the rising antibiotic resistance crisis. Recently, there has been significant interest in polyphenolic natural
Xiaoyun Wang +11 more
doaj +2 more sources
Temperature-responsive regulation of the fermentation of hypocrellin A by Shiraia bambusicola (GDMCC 60438) [PDF]
Microbial Cell Factories, 2022 Background Hypocrellin A (HA) is a perylene quinone pigment with high medicinal value that is produced by Shiraia bambusicola Henn. (S. bambusicola) and Hypocrella bambusae (Berk. & Broome) Sacc.
Yongdi Wen +4 more
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Effects of 5-Azacytidine on Growth and Hypocrellin Production of Shiraia bambusicola [PDF]
Frontiers in Microbiology, 2018 Hypocrellins, fungal perylenequinones of Shiraia bambusicola are developed as important photodynamic therapy agents against cancers and viruses. Due to the limitation of the wild resources, the mycelium culture is a promising alternative for hypocrellin ...
Yan Jun Ma, Can Song Lu, Jian Wen Wang
doaj +2 more sources
Interplay between Shiraia and its fruiting body-associated Rhodococcus sp. No. 3 via hypocrellin A and carotenoid biosynthesis [PDF]
MycologyHypocrellin A (HA), a bioactive perylenequinone from Shiraia fruiting bodies, serves as an efficient photodynamic therapy photosensitiser. While these fruiting bodies harbour diverse bacteria, host-microbe functional interactions remain poorly ...
Li Ping Zheng +4 more
doaj +2 more sources
Glucose-6-Phosphate Dehydrogenase Modulates Shiraia Hypocrellin A Biosynthesis Through ROS/NO Signaling in Response to Bamboo Polysaccharide Elicitation [PDF]
MoleculesHypocrellin A (HA), a photodynamic perylenequinone pigment from Shiraia fruiting bodies, functions as an efficient photosensitizer for clinical photodynamic therapy.
Xinping Li +4 more
doaj +2 more sources
Endothelial soluble guanylate cyclase enzyme inhibitors as a novel target for the treatment of sepsis-related hypotension [PDF]
Scientific ReportsSepsis-related hypotension is a life-threatening condition due to systemic infection leading to widespread inflammation and blood vessel dilation. This can cause a dramatic drop in blood pressure, impairing blood flow to vital organs and potentially ...
Yousif Ali Ahmed Suleiman +2 more
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Journal of Fungi, 2022 Melatonin (MLT), an evolutionarily conserved pleiotropic molecule, is implicated in numerous physiological processes in plants and animals. However, the effects of MLT on microbes have seldom been reported.
Wenjuan Wang +5 more
doaj +2 more sources
Production of fungal hypocrellin photosensitizers: Exploiting bambusicolous fungi and elicitation strategies in mycelium cultures [PDF]
MycologyHypocrellins, a group of naturally occurring perylenequinone pigments produced by Shiraia bambusicola, are notable for their potential use in photodynamic therapy (PDT) for treating cancers and viruses.
Xin Ping Li +3 more
doaj +2 more sources
Photodynamic Antifungal Activity of Hypocrellin A Against Candida albicans
Frontiers in Microbiology, 2019 Many studies have reported that hypocrellin A (HA) exhibits effective antimicrobial activities with proper irradiation. However, its antifungal activity and the involved mechanism have not been fully defined.
Ke Xu, Jue Wang, Yingzhi Zhuge
exaly +3 more sources