Results 51 to 60 of about 19,540 (227)

Clinical efficacy of prophylactic intravenous immunoglobulin for elderly DLBCL patients with hypogammaglobulinemia in the COVID-19 pandemic era

Frontiers in Oncology
BackgroundElderly patients diagnosed with diffuse large B-cell lymphoma (DLBCL) undergoing reduced intensity R-CHOP therapy are at a heightened risk of acquiring infections, notably coronavirus disease 2019 (COVID-19) infection.
Dong Won Baek, Ga-Young Song, Ho Sup Lee, Young Rok Do, Ji Hyun Lee, Ho-Young Yhim, Joon Ho Moon, Deok-Hwan Yang   +7 more
doaj   +1 more source

Challenges in the Role of Gammaglobulin Replacement Therapy and Vaccination Strategies For Haematological Malignancy.

Frontiers in Immunology, 2016
Patients with chronic lymphocytic leukemia (CLL) and multiple myeloma (MM) are prone to present with antibody production deficits associated with recurrent or severe bacterial infections that might benefit from human immunoglobulin (Ig) (IVIg/SCIg ...
Silvia Sánchez-Ramón, Fatima Dhalla, Helen Chapel, Helen Chapel   +3 more
doaj   +1 more source

Risk factors for Haemophilus influenzae and pneumococcal respiratory tract colonization in CVID [PDF]

, 2018
To the Editor: Disease-specific studies focused on infection risk in common variable immune deficiencies (CVIDs) are needed to define strategies for controlling respiratory infections predominantly due to bacteria such as Streptococcus pneumoniae and ...
Camilli, Romina, Cardines, Rita, Cerquetti, Marina, Ciervo, Alessandra, Giufrè, Maria, Mancini, Fabiola, Milito, Cinzia, Pantosti, Annalisa, Pimentel de Araujo, Fernanda, Pulvirenti, Federica, Quinti, Isabella   +10 more
core   +1 more source

Sutimlimab in Patients With Cold Agglutinin Disease (CAD): Results From a Managed Access Program

European Journal of Haematology, EarlyView.
ABSTRACT Cold agglutinin disease (CAD) is a low‐grade lymphoproliferative disorder accounting for 15%–30% of patients suffering from autoimmune hemolytic anemias. The clonal B cells produce autoantibodies primarily of the IgM‐κ class that cause agglutination of red blood cells (RBCs) at temperatures ≤ 37°C and activate the classical complement pathway ...
Sandra Maria Frey, Pauline Halberstadt, Ferras Alashkar, Veronika Lenz, H. Christian Reinhardt, Alexander Röth   +5 more
wiley   +1 more source

IgM Augments Complement Bactericidal Activity with Serum from a Patient with a Novel CD79a Mutation [PDF]

, 2018
Antibody replacement therapy for patients with antibody deficiencies contains only IgG. As a result, concurrent IgM and IgA deficiency present in a large proportion of antibody deficient patients persists.
Burg, M. (Mirjam) van der, Flier, M. (Michiel) van der, Henriet, S.S.V. (Stefanie S.V.), Jonge, M.I. (Marien) de, Kuipers, S. (Saskia), Langereis, J.D. (Jeroen), Weemaes, C.M.R. (Corry)   +6 more
core   +1 more source

Factors Affecting Immune Reconstitution Post‐Allogeneic HSCT in Children: The Case for an Individualized Approach to Vaccination

European Journal of Haematology, EarlyView.
ABSTRACT Allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used to treat malignant and non‐malignant diseases. Following allogeneic HSCT, patients are particularly vulnerable to vaccine‐preventable diseases (VPD) because conditioning depletes immune cells, including memory cells.
Hélène Buvelot, Frederic Baleydier, Laure Pittet, Geraldine Blanchard‐Rohner   +3 more
wiley   +1 more source

Infectious Complications Reporting in Common Variable Immunodeficiency: A Systematic Review and Meta-analysis

Oman Medical Journal, 2020
Objectives: Common variable immunodeficiency (CVID) is a heterogeneous disorder characterized by hypogammaglobulinemia and increased susceptibility to recurrent infections.
Hamed Zainaldain, Fatema Sadaat Rizvi, Hosein Rafiemanesh, Mahla Alizadeh, Mahnaz Jamee, Sara Mohammadi, Fatemeh Kiaee, Hamed Mohammadi, Farhad Babaie, Reza Yazdani, Hassan Abolhassani, Asghar Aghamohammadi, Gholamreza Azizi   +12 more
doaj   +1 more source

Brain abscess following rituximab infusion in a patient with pemphigus vulgaris. [PDF]

, 2015
BackgroundImmunocompromised patients are at increased risk for developing meningitis or, rarely, brain abscess with opportunistic organisms like Listeria monocytogenes.Case reportA 52 year-old Saudi Arabian woman who was diagnosed with pemphigus vulgaris
Al-Harbi, Talal M, Al-Muammar, Shahad A, Ellis, Ronald J   +2 more
core   +2 more sources

Cost‐Effectiveness Analysis of Second‐Line Lisocabtagene Maraleucel in the Treatment of Refractory or Relapsed Large B‐Cell Lymphoma

European Journal of Haematology, EarlyView.
ABSTRACT Objectives CAR‐T cell therapies such as lisocabtagene maraleucel (liso‐cel) have transformed the treatment of patients with second line primary refractory or early relapsed ≤ 12 months (R/R) large B‐cell lymphoma (LBCL). The objective of this study was to assess the cost‐effectiveness of liso‐cel compared to standard of care (SOC) to treat R/R
Catherine Thieblemont, Florian Colrat, Rahma Sellami, Marine Sivignon, Adrien Petel, Sébastien Branchoux, Gérard de Pouvourville   +6 more
wiley   +1 more source

A retrospective study on 195 horses with contaminated and infected synovial cavities [PDF]

, 2009
This study analyzes the clinical aspects of contaminated and infected synovial cavities in horses and evaluates their prognosis after treatment. The medical records of 195 affected horses referred between June 1999 and July 2004 were reviewed. Twenty-six
Dewulf, Jeroen, Dumoulin, Michèle, Gasthuys, Frank, Martens, Ann, Oosterlinck, Maarten, Pille, Frederik   +5 more
core   +1 more source