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Neonatal Hypoglycemia

Seminars in Fetal and Neonatal Medicine, 2016
A consistent definition for neonatal hypoglycemia in the first 48 h of life continues to elude us. Enhanced understanding of metabolic disturbances and genetic disorders that underlie alterations in postnatal glucose homeostasis has added useful information to understanding transitional hypoglycemia.
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Hyperinsulinemic Hypoglycemia

Pediatric Clinics of North America, 2015
In hyperinsulinemic hypoglycemia (HH) there is dysregulation of insulin secretion from pancreatic β-cells. Insulin secretion becomes inappropriate for the level of blood glucose leading to severe hypoglycemia. HH is associated with a high risk of brain injury because insulin inhibits lipolysis and ketogenesis thus preventing the generation of ...
Maria, Güemes, Khalid, Hussain
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Reactive hypoglycemia

Metabolism, 1975
Reactive hypoglycemia is a relatively uncommon meal-induced hypoglycemic disorder. Most patients with adrenergic-mediated symptoms have a diagnosis other than reactive hypoglycemia. In many patients with this self-diagnosis, other disorders can be attributed as a cause for symptoms, especially neuropsychiatric disease.
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Persistent Hypoglycemia

Pediatric Emergency Care, 2013
Hypoglycemia is a common finding in emergency departments. In this article, we review the causes of hypoglycemia in children, the evaluation and management of a child with persistent hypoglycemia, and causes of adrenal insufficiency in children. We report a case of adrenoleukodystrophy, a type of primary adrenal insufficiency, in a 5-year-old boy who ...
Kelly Anne, Levasseur   +2 more
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Hypoglycemia unawareness

Diabetes Research and Clinical Practice, 2011
Iatrogenic hypoglycemia is the limiting factor in the glycemic control of diabetes. It causes recurrent symptomatic and sometimes, at least temporally, disabling episodes in most people with type 1 diabetes, as well as in many with advanced type 2 diabetes.
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Newborn hypoglycemia

Journal of Pediatric Health Care, 1999
Neonatal hypoglycemia is a common problem encountered by both term and preterm infants. It can be either symptomatic or asymptomatic. Prolonged hypoglycemia may result in permanent neurologic impairment and death. Definitions of hypoglycemia vary and remain controversial.
D, Armentrout, J, Caple
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Factitious Hypoglycemia

Pediatrics, 1982
Insulin abuse resulting in hypoglycemia was originally reported in 1947.1,2 However, not until the 1970s was the serum C-peptide level recognized to be a reliable marker of pancreatic β-cell activity.3 Human C-peptide radioimmunoassay has been advocated recently as a useful test in diagnosing insulin-induced factitious hypoglycemia.4,5 This report ...
J H, Mayefsky   +2 more
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Neonatal Hypoglycemia

Neonatal Network
Neonatal hypoglycemia (NH) is broadly defined as a low plasma glucose concentration that elicits hypoglycemia-induced impaired brain function. To date, no universally accepted threshold (reference range) for plasma glucose levels in newborns has been published, as data consistently indicate that neurologic responses to hypoglycemia differ at various ...
Kiley, Edmundson, Amy J, Jnah
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Neonatal Hypoglycemia

Neonatology, 1990
Neonatal hypoglycemia is particularly dangerous for the brain when it is symptomatic or/and recurrent. In order to avoid symptomatic hypoglycemia a compensatory production of ketone bodies is required since they are actively taken up by the neonatal brain. Recurrent hypoglycemia can be avoided by stimulation of neonatal gluconeogenesis which is limited
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AUTOIMMUNE HYPOGLYCEMIA

Endocrinology and Metabolism Clinics of North America, 1999
Autoimmune hypoglycemia is a rare but fascinating syndrome of hypoglycemia caused by the interaction of endogenous antibodies with insulin or the insulin receptor. Awareness of autoimmune hypoglycemia is important because the syndrome may produce severe neuroglycopenic symptoms and may be confused with the presence of an insulinoma. A correct diagnosis
J B, Redmon, F Q, Nuttall
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