Results 181 to 190 of about 118,339 (295)

The Efficacy and Safety of Atenolol for Treatment of Infantile Hemangioma

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Infantile hemangiomas are the most common benign vascular tumours in children. Since the discovery of propranolol for infantile hemangiomas, its increasing side effect profile has prompted research into its beta‐1‐selective counterpart, atenolol.
Michelle Shi   +3 more
wiley   +1 more source

Phase IIb Trial for the Palliative Treatment of Patients With Primary Hepatic Malignancy Unable to Receive Curative Treatment: Efficacy of Colchicine

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This trial was to evaluate the efficacy and the safety of colchicine for the palliative treatment of patients with primary hepatic malignancy unable to receive curative treatment. Forty hepatocellular carcinoma (HCC) patients and two intrahepatic cholangiocarcinoma (ICC) patients signed the informed consents.
Zu‐Yau Lin   +8 more
wiley   +1 more source

Lysosome Evanescence Mediates Autophagic Flux Impairment in Glucose Imbalanced Environments

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Schwann cells (SCs) support axonal function and promote nerve regeneration. This study investigated how various glucose concentrations influence SC viability, oxidative stress, and autophagy, which contribute to diabetic neuropathy. RSC96 SCs were cultured under five glucose conditions (0, 2.5, 5.5, 50, or 100 mM) for 24, 48, and 72 h.
Yuan‐Chen Cheng   +6 more
wiley   +1 more source

Associations Between Initial Glycated Hemoglobin at Diabetes Diagnosis, Longitudinal Changes and Medication Effects, and the Severity and Progression of Sight‐Threatening Diabetic Retinopathy

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic retinopathy (DR) is a leading cause of vision impairment in patients diagnosed with Type 2 diabetes mellitus (T2DM). Awareness of risk factors is necessary to reduce or prevent harmful effects of DR such as irreversible vision loss, and to help ensure early treatment.
Yu‐Chi Sung   +8 more
wiley   +1 more source

Alogliptin Reduces Oxidative Stress in Cardiomyocytes and Ameliorates Diabetic Cardiomyopathy via the AURKB/NLGN2 Signaling

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cardiomyopathy (DCM) is a common complication of diabetes mellitus. This study investigated the effects of alogliptin on DCM and its underlying mechanisms. A DCM model was constructed and treated with alogliptin. Downstream targets of alogliptin were screened using bioinformatics analysis.
Li‐Jing Jiao   +7 more
wiley   +1 more source

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