Results 81 to 90 of about 228,932 (402)

Coacervates Composed of Low‐Molecular‐Weight Compounds– Molecular Design, Stimuli Responsiveness, Confined Reaction

Advanced Biology, EarlyView.
Coacervation driven by liquid‐liquid phase separation (LLPS) of biopolymers has garnered increasing attention in biology since this leads to the formation of membraneless organelles capable of performing essential yet largely unknown functions. This review highlights recent advances in coacervates (artificial condensates) composed of low‐molecular ...
Sayuri L. Higashi, Masato Ikeda
wiley   +1 more source

Bayesian Optimization Assisted Meal Bolus Decision Based on Gaussian Processes Learning and Risk-Sensitive Control [PDF]

arXiv, 2021
Effective postprandial glucose control is important to glucose management for subjects with diabetes mellitus. In this work, a data-driven meal bolus decision method is proposed without the need of subject-specific glucose management parameters. The postprandial glucose dynamics is learnt using Gaussian process regression.
arxiv  

Central Mechanisms of Glucose Sensing and Counterregulation in Defense of Hypoglycemia.

Endocrine reviews, 2019
Glucose homeostasis requires an organism to rapidly respond to changes in plasma glucose concentrations. Iatrogenic hypoglycemia as a result of treatment with insulin or sulfonylureas is the most common cause of hypoglycemia in humans and is generally ...
S. Stanley, A. Moheet, E. Seaquist
semanticscholar   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray, Shehzahdi S. Moonshi, Hang Thu Ta   +2 more
wiley   +1 more source

Sex differences in body composition in youth with type 1 diabetes and its predictive value in cardiovascular disease risk assessment

Diabetes/Metabolism Research and Reviews, Volume 39, Issue 1, January 2023., 2023
Abstract Background Women with type 1 diabetes (T1D) are more susceptible than men to cardiovascular disease (CVD). Signs of increased risk may already appear among adolescent girls. Objectives We explored the contribution of body composition to the development of CVD risk factors among youth with T1D.
Avivit Brener, Sandy Hamama, Hagar Interator, Asaf Ben Simon, Irina Laurian, Anna Dorfman, Efrat Chorna, Michal Yackobovitch‐Gavan, Asaf Oren, Ori Eyal, Yael Lebenthal   +10 more
wiley   +1 more source

Hypoglycemia: The neglected complication

Indian Journal of Endocrinology and Metabolism, 2013
Hypoglycemia is an important complication of glucose-lowering therapy in patients with diabetes mellitus. Attempts made at intensive glycemic control invariably increases the risk of hypoglycemia.
Sanjay Kalra, Jagat Jyoti Mukherjee, Subramanium Venkataraman, Ganapathi Bantwal, Shehla Shaikh, Banshi Saboo, Ashok Kumar Das, Ambady Ramachandran   +7 more
doaj   +1 more source

Clopidogrel-induced non-diabetic hypoglycemia reported from Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia: a case report

Journal of Medical Case Reports, 2023
Background Recurrent episodes of hypoglycemia may be caused by several factors, including drugs, critical illnesses, hormonal deficiency, non-islet cell tumor endogenous hyperinsulinism, and accidental, surreptitious, or malicious hypoglycemia.
Kibret Enyew Belay, Saba Belay Urge, Yidnekachew Asrat Birhan, Paulos Efrem, Theodros Aberra Alemneh   +4 more
doaj   +1 more source

Intermittent Control for Safe Long-Acting Insulin Intensification for Type 2 Diabetes: In-Silico Experiment [PDF]

arXiv, 2023
Around a third of type 2 diabetes patients (T2D) are escalated to basal insulin injections. Basal insulin dose is titrated to achieve a tight glycemic target without undue hypoglycemic risk. In the standard of care (SoC), titration is based on intermittent fasting blood glucose (FBG) measurements.
arxiv  

Severe hypoglycemia and the risk of cardiovascular disease and mortality in type 2 diabetes: a nationwide population-based cohort study

Cardiovascular Diabetology, 2019
BackgroundWe investigated the association regarding severe hypoglycemia episodes with cardiovascular disease risk and all-cause mortality in patients with type 2 diabetes.MethodsBaseline and follow-up data (n = 1,568,097) from patients with type 2 ...
J. Yun, Y. Park, Kyungdo Han, S. Cha, Y. Ahn, Seung-Hyun Ko   +5 more
semanticscholar   +1 more source

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

Advanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania, Manus J. P. Biggs, Katarzyna Krukiewicz   +2 more
wiley   +1 more source