Results 11 to 20 of about 136,109 (177)

Differential Expression of Inflammatory Markers in Hypoglycemia Unawareness Associated with Type 1 Diabetes: A Case Report [PDF]

Brain Sciences, 2020
The recurrence of hypoglycemic episodes leads to attenuation of the normal counter-regulatory mechanisms that are controlled by the hypothalamus, which results in hypoglycemia unawareness (HU).
Yousef Al Zoubi, Bashair M. Mussa, Ankita Srivastava, Abdul Khader Mohammed, Elamin Abdelgadir, Alaaeldin Bashier, Fatheya Al Awadi, Salah Abusnana   +7 more
doaj   +5 more sources

A New Role for Hypothalamic Glucose-Sensing Neurons in Hypoglycemia Unawareness. [PDF]

Diabetes, 2023
The mammalian brain uses glucose for much of its daily energy needs. Neurons have the highest energy demand in the adult brain and thus require continuous delivery of glucose from the blood.
Fioramonti X.
europepmc   +4 more sources

Persistent Postgastrectomy Hypoglycemia Unawareness in Patients With Gastric Cancer Unveiled by a Prospective Study [PDF]

Annals of Surgery Open, 2022
Objective:. Late dumping syndrome is a common postgastrectomy complication characterized by reactive hypoglycemia. This study aimed to explore the glycemic trend in patients who underwent gastrectomy for gastric cancer and clarify its changes over time ...
Takeshi Kubota, MD, PhD, Masayuki Yubakami, MD, Emi Ushigome, MD, PhD, Takuma Ohashi, MD, PhD, Katsutoshi Shoda, MD, PhD, Hirotaka Konishi, MD, PhD, Atsushi Shiozaki, MD, PhD, Hitoshi Fujiwara, MD, PhD, Kazuma Okamoto, MD, PhD, Michiaki Fukui, MD, PhD, Eigo Otsuji, MD, PhD   +10 more
doaj   +3 more sources

Association Between Time in Range and Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients with Hypoglycemia Unawareness: A Single-center Retrospective Study. [PDF]

Int J Gen Med
Aim Our study aimed to investigate the association between time in range (TIR) and diabetic retinopathy (DR) in type 2 diabetes mellitus (T2DM) patients with hypoglycemia unawareness. Methods This is a retrospective cross-sectional study.
Xu C, Dai W, Liu Y, Zhang R, Shi E, Shan X, Cao Y.   +6 more
europepmc   +4 more sources

Continuous glucose monitoring in a patient with insulinoma presenting with unawareness of postprandial hypoglycemia [PDF]

Endocrinology, Diabetes & Metabolism Case Reports, 2023
Unawareness of postprandial hypoglycemia for 5 years was identified in a 66-year-old man at a local clinic. The patient was referred to our hospital because of this first awareness of hypoglycemia (i.e.
Rikako Nakajima, Hiroto Idesawa, Daisuke Sato, Jun Ito, Kei Ito, Masanao Fujii, Takamichi Suzuki, Tomoaki Furuta, Hitomi Kawai, Norio Takayashiki, Masanao Kurata, Hiroaki Yagyu   +11 more
doaj   +3 more sources

Association between hypoglycemia unawareness and cardiovascular autonomic neuropathy in patients with type 2 diabetes mellitus: a prospective cohort study [PDF]

Diabetology & Metabolic Syndrome
Background Diabetes has emerged as the third most significant global public health challenge. Among patients with type 2 diabetes mellitus (T2DM), cardiovascular autonomic neuropathy (CAN) represents a prevalent yet frequently overlooked complication ...
Siqi Li, Xiangxiang Shan, Xing Wei, Wu Dai, Yonghong Cao   +4 more
doaj   +3 more sources

Diagnosis and Treatment Course of Insulinoma Presenting as Hypoglycemia Unawareness Using a Factory-Calibrated Continuous Glucose Monitoring System. [PDF]

Am J Case Rep, 2022
Patient: Male, 35-year-old Final Diagnosis: Insulinoma Symptoms: Loss of consciousness Medication:— Clinical Procedure: — Specialty: Endocrinology and Metabolic • Metabolic Disorders and Diabetics Objective: Rare disease Background: Insulinoma presenting
Aida A, Noto H.
europepmc   +3 more sources

OR03-6 Further Clinical Evaluation of Stem Cell-Derived Islet Replacement Therapy (VC-02) Demonstrates Production of C-Peptide with Improvements in Glycemic Control Parameters in Multiple Patients with Type 1 Diabetes and Hypoglycemia Unawareness [PDF]

J Endocr Soc, 2022
VC-02 combination product (PEC-Direct) is a clinical-stage regenerative medicine therapy being developed for patients with type 1 diabetes and hypoglycemia unawareness intended to restore homeostatic glycemic control. It is comprised of stem cell-derived
Melena D. Bellin, Mark Daniel, Howard L. Foyt, Bart Keymeulen, Timothy J. Kieffer, Evert Kroon, Daniël Pipeleers, David Thompson, Richard Wang, Manasi Jaiman   +9 more
europepmc   +4 more sources

Decreasing hypoglycemia unawareness in a patient with type 1 diabetes mellitus after continuous glucose monitoring: tools for self-care

Revista de la Facultad de Medicina Humana, 2022
Diabetes mellitus is a public health problem that causes early and late complications. Continuous glucose monitoring (CGM) has become the main technological tool for real-time glycemic control and has the potential to prevent complications.
Sonia H. Perez Cavero, Helard Manrique-Hurtado, Julio Leey-Casella   +2 more
doaj   +4 more sources

Atypical Presentation of Insulinoma in a Patient With Hypoglycemia Unawareness: A Case Report [PDF]

Cureus
Insulinomas are uncommon tumors in the pancreas that result in the overproduction of insulin, which can cause frequent episodes of low blood sugar. While most patients present with typical symptoms such as confusion and diaphoresis, some may experience ...
Abdelgadir A, Li Voon Chong J.
europepmc   +4 more sources