Results 141 to 150 of about 127,164 (309)

KLF15 as a Metabolic Gatekeeper Linking Drug Metabolism, Toxicity, and Precision Therapeutics

iNew Medicine, EarlyView.
KLF15‐mediated metabolic preconditioning links metabolic state to drug disposition, therapeutic efficacy, and adverse effects, extending classical xenobiotic sensing toward precision pharmacology. ABSTRACT Krüppel‐like factor 15 (KLF15) is emerging as a metabolic‐state‐sensitive regulator of hepatic endobiotic and xenobiotic metabolism.
Shilin Li, Xue Li, Zhengding Su, Shuxin Han   +3 more
wiley   +1 more source

Investigation of the Hypoglycemic Effect of Tribulus terrestris Extract on Diabetic Rats

Journal of Medicinal Plants, 2008
Background: Tribulus terrestris L. is a traditional herbal medicine used for treatment of hypertension, urinary tract inflammation, kidney and bladder stones.
A Bonakdaran, H Fallah Huseini, F Khalighi-Sigaroodi, M Abdoli, M Ahvazi   +4 more
doaj  

Hypoglycemic and analgesic activity of ethanol extract of polyalthia longifolia leaves on experimental mice

, 2018
Hypoglycemic and analgesic activity of ethanol extract of polyalthia longifolia leaves on experimental ...
A Rahman (9350000), T Rahman (9876398), A Islam (9860528), GTA Chowdhury (15815876), A Habib (7790162), AK Azad (14646437), M Khairuzzaman (13455801), J Ferdous (13381410)   +7 more
core  

Protective Effects of Imeglimin Against Oxaliplatin‐Induced Peripheral Neurotoxicity: Evidence From In Vitro and In Vivo Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Oxaliplatin is a platinum‐based anticancer agent widely used for gastrointestinal malignancies; however, it is known to cause dose‐dependent peripheral neuropathy (OIPN), a characteristic adverse effect. OIPN results in a reduced quality of life and often necessitates dose reduction or discontinuation of oxaliplatin; however, effective ...
Yusuke Koura, Kano Kinjo, Keisuke Mine, Yusuke Mori, Mami Ueda, Risa Kaneko, Yuna Kamiya, Taiga Sonoda, Haruka Mimata, Shunsuke Fujita, Takehiro Kawashiri, Daisuke Kobayashi   +11 more
wiley   +1 more source

SIFAT HIPOGLIKEMIK DAN HIPOKOLESTEROLEMIK PROTEIN KEDELAI PADA TIKUS MODEL TOLERANSI GLUKOSA TERGANGGU (TGT) INDUKSI ALLOKSAN [Hypoglycemic and Hypocholesterolemic Activities of Soy Protein on Impared Glucose Intolerant Rats Induced by Alloxan]

Jurnal Teknologi dan Industri Pangan, 2002
Previous studies indicated that soy protein had hypoglycemic and hypocholesterolemic activity in induced diabetic rats. However when combined with different sources of carbohydrate, the effects were not known yet.
Masun Lasimo 1 ), Zuheid Noor 2), Y. Marsono 2)   +2 more
doaj  

Phenotypic and Genotypic Analysis of Two Rare Cases of ‐‐SEA/‐α4.3 HbH Disease

Journal of Clinical Laboratory Analysis, EarlyView.
We report two unrelated adult patients with rare deletional HbH disease (genotype ‐‐SEA/‐α4.3). This novel 4.3 kb deletion covering the HBA1 gene is accompanied by X‐Y‐Z segment recombination, which was identified by CycloneSEQ long‐read nanopore sequencing.
Weijia Yang, Xiaoyan Huang, Li Zhang, Xiaoqin Yang, Yaya Guo, Qingping Kang, Min Dou, Guijun Huang   +7 more
wiley   +1 more source

Hypoglycemic and analgesic activity of ethanol extract of polyalthia longifolia leaves on experimental mice

, 2019
Hypoglycemic and analgesic activity of ethanol extract of polyalthia longifolia leaves on experimental ...
A Rahman (9350000), T Rahman (9876398), G Tawabul Alam Chowdhury (13455807), A Islam (9860528), A Habib (7790162), AK Azad (14646437), M Khairuzzaman (13455801), J Ferdous (13381410)   +7 more
core  

Dose–Response Relationship Between Triglyceride Glucose‐Waist Height Ratio Index and Cardiometabolic Multimorbidity Among Chinese Middle‐Aged and Older People

Journal of Clinical Laboratory Analysis, EarlyView.
Using data from 6674 middle‐aged and older Chinese adults in the China Health and Retirement Longitudinal Study (CHARLS), this study investigated the association between the triglyceride glucose‐waist height ratio (TyG‐WHtR) index and cardiometabolic multimorbidity (CMM).
Lingling Li, Zongliang Yu, Yixuan Feng, Changxin Sun, Lanqing Hu, Xinyi Liu, Liang Li, Min Wu, Longtao Liu   +8 more
wiley   +1 more source

Pancreas–Intestine Composite Transplantation for Simultaneous Loss of Pancreatic and Intestinal Function (With Video)

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Pancreas–intestine composite transplantation (PITx) is a therapeutic option for patients with irreversible loss of both pancreatic and intestinal function. We report a case of PITx in a 16‐year‐old male who developed fulminant Type 1 diabetes mellitus complicated by non‐occlusive mesenteric ischemia, resulting in extensive intestinal necrosis.
Kei Yamane, Takashi Ito, Takayuki Anazawa, Junji Fujikura, Makoto Okabe, Satoshi Ishida, Koki Kurahashi, Masaaki Hirata, Hiroshi Kawamoto, Hiroto Nishino, Asahi Sato, Tomoaki Yoh, Hidenobu Kojima, Shinya Okumura, Takahiro Nishio, Daisuke Ueda, Hirofumi Hirao, Yuki Masano, Shoichi Kageyama, Katsunori Sakamoto, Satoshi Ogiso, Kazuyuki Nagai, Yoichiro Uchida, Takamichi Ishii, Etsuro Hatano   +24 more
wiley   +1 more source

Inpatient continuous glucose monitoring halves the risk of hypoglycemia in patients with hyperinsulinism. [PDF]

Front Endocrinol (Lausanne)
Chandra C, De Silva S, Worthington S, Banerjee I, Worth C.   +4 more
europepmc   +1 more source