Results 131 to 140 of about 117,020 (312)

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source

Hypoglycemic Diterpenoids from Tinospora crispa

, 2016
Three new diterpenoids, 2-O-lactoylborapetoside B (1), 6′-O-lactoylborapetoside B (2), and tinocrispol A (3), and nine known diterpenoids (4–12) were isolated from an EtOH extract of Tinospora crispa vines.
Shoei-Sheng Lee (688345), Chi-Tun Ruan (2110405), Ming-Jai Su (286917), Po-Hung Hsieh (2110411), Sio-Hong Lam (2110408)   +4 more
core   +1 more source

Neonatal seizures: Advances in diagnosis and management

Epilepsia Open, EarlyView.
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz, Ronit M. Pressler, Eli M. Mizrahi   +2 more
wiley   +1 more source

Treatment of gestational diabetes: oral hypoglycemic agents or insulin? [PDF]

, 2011
Our report aims to verify whether perinatal maternal glycemic control in gestational diabetes can only be achieved with insulin or with oral hypoglycemic agents.
Renda, Eliana, Giorgio, Elsa, valenti , Oriana, Hyseni, Entela, Monte, Santo, De Domenico, Roberta, Faraci, Marianna, Di Prima, Fosca A. F.   +7 more
core  

Real‐world‐data for phenotypes and genotypes of rare monogenic genetic epilepsies and genes of uncertain significance for epilepsy

Epilepsia Open, EarlyView.
Abstract Objectives The objectives of this study were to develop a real‐world‐data (RWD) database for patients with epilepsy to provide further real‐world‐evidence (RWE) for monogenic genetic epilepsies; to assess the usefulness of a diagnostic algorithm in epilepsy; and to examine protein 3D structures using in silico tools to predict variant ...
Haley Morris, Elizabeth Mathew, Shalini Bahl, Marta Villa‐Lopez, Saadet Mercimek‐Andrews   +4 more
wiley   +1 more source

Research Progress on Hypoglycemic Effects and Molecular Mechanisms of Flavonoids: A Review

Antioxidants
As a prevalent metabolic disorder, the increasing incidence of diabetes imposes a significant burden on global healthcare. Flavonoids in natural phytochemical products exhibit notable hypoglycemic properties, making them potential alternatives for ...
Mengyi Liu, Chunlong Liu, Puba Zhaxi, Xiaohong Kou, Yazhou Liu, Zhaohui Xue   +5 more
doaj   +1 more source

Securigenin glycosides as hypoglycemic principles of Securigera securidaca seeds

, 2017
Seeds of Securigera securidaca (Fabaceae) are used in Iranian folk medicine as an antidiabetic treatment. In this study, the antihyperglycemic activity of chloroform and methanol fractions (CF and MF) from S.
Moradi-Afrapoli, Fahimeh, Goodarzi, Saied, Hamburger, Matthias, Ebrahimi, Samad Nejad, Yassa, Narguess, Abdollahi, Mohammad, Neuburger, Markus, Tofighi, Zahra, Hadjiakhoondi, Abbas   +8 more
core   +1 more source

Ketogenic diet therapy for children with super‐refractory status epilepticus in intensive care: International clinical practice recommendations

Epilepsia Open, EarlyView.
Abstract Objective We aimed to create practical recommendations to support healthcare teams starting ketogenic diet therapy (KDT) for children with super‐refractory status epilepticus in intensive care settings. Methods A literature review was conducted to extract published data on patient selection, diet prescription, diet initiation, monitoring, fine‐
Robyn Blackford, Victoria J. Whiteley, Isobel Hardy, Marisa Armeno, Tessa Bollard, J. Helen Cross, Christin Eltze, Susan George, Charlotte Howard, A. Laura Nijstad, Erin Talzzia, Chris Paget, Samiran Ray, Zoe Simpson, Elizabeth Song‐Pozderac, Agnieszka Szmurlo, Charlene Tan‐Smith, Lisa Vanatta, Elles van der Louw, Natasha E. Schoeler, on behalf of the Ketogenic Dietitians Research Network   +20 more
wiley   +1 more source

Hypoglycemic effect of extracts of Petai Papan (Parkia speciosa, Hassk) [PDF]

, 1993
The oml administration of the chloroform extract of Parkia speciosa to alloxan-induced diabetic rats produced a significant ...
Mohamed, Suhaila, Jamaludin, Fathaiya
core  

Glucose and Loss of Control Eating: Evidence From Naturalistic Assessment After Roux‐en‐Y Gastric Bypass

European Eating Disorders Review, EarlyView.
ABSTRACT Objective While loss of control (LOC) eating is associated with poor outcomes following metabolic and bariatric surgery (MBS), the mechanisms driving it are less understood. This study used momentary, naturalistic data to examine glucose as a biological correlate of LOC eating after Roux‐en‐Y gastric bypass (RYGB).
Gail A. Kerver, Kristine J. Steffen, Debra L. Safer, Glen Forester, David B. Sarwer, Stephen A. Wonderlich, Scott G. Engel   +6 more
wiley   +1 more source