Results 71 to 80 of about 117,020 (312)

Brain Calcium Metabolism in Hypoglycemic Coma

, 1993
The present experiments were designed to provide information on brain calcium metabolism during hypoglycemic coma. We specifically wished to evaluate changes in extracellular calcium concentration (Ca2+e) during prolonged hypoglycemic coma and recovery ...
Tibor Kristián, Gunilla Gidö, Bo K. Siesjö   +2 more
core   +1 more source

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

Isolation, structural characterization, and hypoglycemic activity of polysaccharides from the stems of Panax ginseng C. A. Meyer

Frontiers in Sustainable Food Systems
The purpose of this study was to obtain polysaccharides from Panax ginseng C. A. Meyer stems (PGSPs), agro-byproducts with development potential, and fully explore the potential value in P. ginseng stems. Two novel polysaccharides firstly from P. ginseng
Weiwei Xu, Wei Zhou, Jinfeng Sun, Weiwei Chen, Xuanye Wu, Tong Guan, Yilin Zhao, Pengcheng Yang, Zhengyu Hu, Gao Li   +9 more
doaj   +1 more source

Hypoglycemic activity and constituents analysis of blueberry (Vaccinium corymbosum) fruit extracts

, 2018
Weifeng Huang,1 Liangliang Yao,2 Xiao He,1 Lei Wang,1 Mingxi Li,3 Youxin Yang,3 Chunpeng Wan3–5 1Department of Microbiology and Immunology, Medical College, China Three Gorge University, Yichang, Hubei 443002, China; 2Affiliated Hospital of Jiangxi
Yao L, Yang YX, Wan C, Huang W, He X, Li M, Wang L   +6 more
core  

Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection

Animal Models and Experimental Medicine, EarlyView.
Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley   +1 more source

Estimating the risk of severe hypoglycemic event related to glucose-lowering treatment among Italian patients with diabetes: the HYPOTHESIS database

, 2017
Silvio Mazzi,1 Roberto Ravasio,1 Gabriele Forlani,2 Giacomo Veronese,2 Andrea Fabbri,3 Giulio Marchesini2 1Department of Health Economics, Health Publishing & Services Srl, Milan, 2Unit of Metabolic Diseases and Clinical Dietetics, “Alma Mater
Veronese G, Marchesini G, Forlani G, Fabbri A, Ravasio R, Mazzi S   +5 more
core  

Hypoglycemic Seizures and Cognitive Function

, 1999
The effect of hypoglycemic seizures on cognitive function was evaluated in 16 children treated for insulin-dependent diabetes mellitus at the Hospital for Sick Children, Toronto ...
J Gordon Millichap
core   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Hypoglycemic agents and potential anti-inflammatory activity

, 2016
Vishal Kothari,1 John A Galdo,2 Suresh T Mathews3 1Department of Nutrition and Dietetics, Boshell Diabetes and Metabolic Diseases Research Program, Auburn University, Auburn, 2Department of Pharmacy Practice, 3Department of Nutrition and Dietetics ...
Kothari V, Galdo JA, Mathews ST
core  

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola, Philip Mease, Alan Kivitz, Naveed Sattar, Laura C. Coates, Daniel Aletaha, Cynthia E. Kartman, Peter Fischer, Luna Sun, Píndaro Martínez‐Osuna, Andris Kronbergs, Purvi Prajapati, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +14 more
wiley   +1 more source