Results 71 to 80 of about 127,164 (309)

Isolation, structural characterization, and hypoglycemic activity of polysaccharides from the stems of Panax ginseng C. A. Meyer

Frontiers in Sustainable Food Systems
The purpose of this study was to obtain polysaccharides from Panax ginseng C. A. Meyer stems (PGSPs), agro-byproducts with development potential, and fully explore the potential value in P. ginseng stems. Two novel polysaccharides firstly from P. ginseng
Weiwei Xu, Wei Zhou, Jinfeng Sun, Weiwei Chen, Xuanye Wu, Tong Guan, Yilin Zhao, Pengcheng Yang, Zhengyu Hu, Gao Li   +9 more
doaj   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Hypoglycemic activity and constituents analysis of blueberry (Vaccinium corymbosum) fruit extracts

, 2018
Weifeng Huang,1 Liangliang Yao,2 Xiao He,1 Lei Wang,1 Mingxi Li,3 Youxin Yang,3 Chunpeng Wan3–5 1Department of Microbiology and Immunology, Medical College, China Three Gorge University, Yichang, Hubei 443002, China; 2Affiliated Hospital of Jiangxi
Yao L, Yang YX, Wan C, Huang W, He X, Li M, Wang L   +6 more
core  

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

British Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen, Michaela Sommer, Annette Zschiesche, Verena Angerer, Martin Scheu, Florian Eyer, Johannes Nadler, Volker Auwärter   +7 more
wiley   +1 more source

Pharmacometric evaluation of pre‐referral rectal artesunate in children with severe malaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Parenteral artesunate is the preferred first‐line treatment for severe malaria. Pre‐referral rectal artesunate suppositories are recommended where parenteral treatment is inaccessible. In this study, we compared dihydroartemisinin exposure and model‐predicted early parasite clearance following rectal artesunate and intravenous artesunate in ...
Ayorinde Adehin, Marie A. Onyamboko, Caterina Fanello, Nicholas J. White, Nicholas P. J. Day, Richard M. Hoglund, Joel Tarning   +6 more
wiley   +1 more source

Antidiabetic Potential of Medicinal Plants and Their Active Components

Biomolecules, 2019
Diabetes mellitus is one of the major health problems in the world, the incidence and associated mortality are increasing. Inadequate regulation of the blood sugar imposes serious consequences for health.
Bahare Salehi, Athar Ata, Nanjangud V. Anil Kumar, Farukh Sharopov, Karina Ramírez-Alarcón, Ana Ruiz-Ortega, Seyed Abdulmajid Ayatollahi, Patrick Valere Tsouh Fokou, Farzad Kobarfard, Zainul Amiruddin Zakaria, Marcello Iriti, Yasaman Taheri, Miquel Martorell, Antoni Sureda, William N. Setzer, Alessandra Durazzo, Massimo Lucarini, Antonello Santini, Raffaele Capasso, Elise Adrian Ostrander, Atta -ur-Rahman, Muhammad Iqbal Choudhary, William C. Cho, Javad Sharifi-Rad   +23 more
doaj   +1 more source

Hypoglycemic effect of Teucrium polium in rats

, 1997
Hypoglycemic effect of T. polium was studied in healthy rats submitted to glucose tolerance tests. The decoction of T. polium slightly, but not significantly attenuated the glycemia levels when compared with oral antidiabetic agent glicazide.
YILDIZ, ÖZNUR, DENİZ, GÜRBÜZ, Senoz, S., KONUKLUGİL, BELMA, Saygi, S.   +4 more
core  

Hypoglycemic, anticomplement and anti-HIV activities of Spathodea campanulata stem bark

, 1999
Spathodea campanulata stem bark decoction (SCD) has shown hypoglycemic activity in mice. It was separated by column chromatography into different fractions, which were evaluated for their hypoglycemic, anticomplement and anti-HIV activities.
Van Poel, B., B. Van Poel, G. Niyonzima, L. Pieters, Franz, G., E. De Clercq, D. Paper, Witvrouw, M., Paper, D., De Clercq, E., Franz, Gerhard, Paper, D. H., Niyonzima, G., Pieters, L., A.J. Vlietinck, Laekeman, G., Vlietinck, A. J., G. Franz, M. Witvrouw, G. Laekeman, Vlietinck, A.J.   +20 more
core   +1 more source

Current practice and guideline adherence in renal dose adjustment for patients with chronic kidney disease: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed, Ahmed Tehemar, Mohamed Gasimelseed, Ahmed Gharaibeh, Muhammad Abdul Hadi, Kazeem Yusuff, Amani Zidan, Ahmed Awaisu   +7 more
wiley   +1 more source

Hypoglycemic Function of Mulberry Leaf Polysaccharide and 1-Deoxynojirimycin (DNJ)

, 2011
The hypoglycemic function of mulberry leaves polysaccharide and 1-deoxynojirimycin (DNJ) is studied preliminary.The extraction is injected into stomach of mice which have diabetes mellitus caused by alloxan.After observation and detection about blood ...
Bei Wang, Shu Xing Liu, Jun Li Hua
core   +1 more source