Results 61 to 70 of about 117,020 (312)

Diagnostic Odyssey of Atypical Long‐Chain 3‐Hydroxyacyl‐CoA Dehydrogenase Deficiency (LCHADD) Explained by Three Allelic Products From Two Pathogenic Variants

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Long‐chain 3‐hydroxyacyl‐CoA dehydrogenase deficiency (LCHADD) is an autosomal recessive mitochondrial defect of long‐chain fatty acid β‐oxidation, caused by biallelic pathogenic variants in HADHA or HADHB. We report a 22‐year‐old male with an atypically mild presentation of LCHADD who was referred to the Undiagnosed Diseases Network (UDN ...
Yutaka Furuta   +9 more
wiley   +1 more source

HYPOGLYCEMIC ACTIVITY OF ETHANOLIC EXTRACT OF SAURAUIA VULCANI KORTH. LEAVES

open access: yes, 2018
 Objective: The aim of this study was to investigate the hypoglycemic activity of ethanol extract of Saurauia vulcani Korth. leaves.Methods: S. vulcani Korth. leaf powder was extracted by maceration method with ethanol 96%.
Panal Sitorus   +2 more
core   +2 more sources

Unveiling the Chemistry of Citrus Peel: Insights into Nutraceutical Potential and Therapeutic Applications

open access: yesFoods
The recent millennium has witnessed a notable shift in consumer focus towards natural products for addressing lifestyle-related disorders, driven by their safety and cost-effectiveness.
Hussan Munir   +8 more
doaj   +1 more source

Uncovering undetected hypoglycemic events

open access: yes, 2012
Jeff UngerCatalina Research Institute, Chino, CA, USAAbstract: Hypoglycemia is the rate-limiting factor that often prevents patients with diabetes from safely and effectively achieving their glycemic goals.
Unger J
core  

Anti-inflammatory and hypoglycemic activities of alpha-pinene [PDF]

open access: yes, 2017
The aim of this study is to investigate the anti-inflammatory and hypoglycemic activities of alpha-pinene, and to find the median lethal dose (LD50) level in mice. Lethal dose levels of alpha-pinene were investigated using a probit analysis method.
Özbek, Hanefi   +3 more
core   +1 more source

Response of an Infant With Presumed Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) to Ketone Supplementation

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Multiple Acyl‐CoA Dehydrogenase Deficiency (MADD) is an autosomal recessive inborn error of metabolism caused by biallelic pathogenic variants in one of three known genes: ETFA, ETFB, and ETFDH. It can cause multisystem dysfunction, including cardiomyopathy in severe cases.
Yutaka Furuta   +17 more
wiley   +1 more source

Cognition and drug adherence to oral hypoglycemic and antihypertensive agents in older adults

open access: yes, 2019
Hamzah Bakouni,1,2 Lia Gentil,3 Helen-Maria Vasiliadis1–2,41Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada; 2Centre de recherche Charles-Le Moyne – Saguenay–Lac-Saint-Jean sur les ...
Gentil L, Bakouni H, Vasiliadis HM
core  

Hypoglycemic Effect of Methanol Extract of Carica Papaya (Pawpaw) Leaves in Alloxan-Induced Diabetic Rats

open access: yes, 2022
This experiment evaluatedthe hypoglycemic effect of methanol extract of Carica papaya leaves in alloxan-induced diabetic rats. Forty (40) male albino rats were grouped into eight: Group A (normal control), Group B (positive control) were induced and ...
Chinwe E. ORIAKU   +6 more
core   +1 more source

Resolution of Refractory Multifocal Atrial Tachycardia in Costello Syndrome Using Trametinib: A Case Supporting MEK Inhibitors as Targeted, Specific Antiarrhythmic

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Arrhythmias affect approximately half of patients with Costello syndrome (CS, OMIM # 218040), with non‐reentrant atrial tachycardia being the most common. This case describes an infant with Costello syndrome carrying the pathogenic HRAS c.34G>A (p.G12S) variant who developed early‐onset, drug‐refractory multifocal atrial tachycardia (MAT ...
Vanina Taliercio   +11 more
wiley   +1 more source

Phloretin exerts hypoglycemic effect in streptozotocin-induced diabetic rats and improves insulin resistance in vitro

open access: yes, 2017
Xin Shen,1,* Nan Zhou,1,* Le Mi,1 Zishuo Hu,2 Libin Wang,1 Xueying Liu,1 Shengyong Zhang1 1Department of Medicinal Chemistry, School of Pharmacy, 2Student Brigade, The Fourth Military Medical University, Xi’an, Shaanxi, People’s Republic of ...
Liu X   +6 more
core  

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