Results 231 to 240 of about 84,543 (289)

Long‐Term Safety and Efficacy of Once‐Daily and Proactive Twice‐Weekly Roflumilast Cream 0.05% for Mild‐to‐Moderate Atopic Dermatitis in Children Aged 2–5 Years From a 52‐Week, Phase 3 Trial (INTEGUMENT‐OLE)

Pediatric Dermatology, EarlyView.
ABSTRACT Background INTEGUMENT‐PED/NCT04845620, a 4‐week, phase 3 trial, demonstrated efficacy and safety of roflumilast cream 0.05% in children aged 2–5 years with mild‐to‐moderate atopic dermatitis (AD). A phase 3 open‐label extension trial (INTEGUMENT‐OLE [NCT04804605]) investigated long‐term outcomes continuing roflumilast cream for ≤ 56 weeks ...
Lawrence F. Eichenfield, Mercedes E. Gonzalez, Mark Boguniewicz, Tracy Funk, Adelaide A. Hebert, Vimal H. Prajapati, Chesahna Kindred, Rocco Serrao, Lisa Swanson, David Krupa, Scott Snyder, Melissa S. Seal, Diane Hanna, Patrick Burnett, David R. Berk   +14 more
wiley   +1 more source

Opposite kinetics of L-leucine and L-phenylalanine induced insulin release studies with the perfused rat pancreas [PDF]

, 1972
Landgraf, R., Landgraf-Leurs, M. M. C., Schwarz, K., Scriba, Peter Christian   +3 more
core  

Role of antimicrobial photodynamic therapy (aPDT) and systemic resveratrol on immediate implant placement in type 2 diabetic rats

Photochemistry and Photobiology, EarlyView.
This study evaluated the combined effects of antimicrobial photodynamic therapy (aPDT) and systemic resveratrol on bone repair around immediately placed implants in type 2 diabetic rats. Resveratrol improved glycemic control and body weight, while aPDT increased implant stability and bone mineralization.
Letícia Pitol‐Palin, Carolina Sayuri Wajima, Fábio Roberto de Souza Batista, Naara Gabriela Monteiro, Isadora Castaldi Sousa, Valdir Gouveia Garcia, Dóris Hissako Matsushita, Letícia Helena Theodoro, Roberta Okamoto   +8 more
wiley   +1 more source

Glycemic control and blood product quality of Canadian blood donors with diabetes

Transfusion, EarlyView.
Abstract Background Many blood centers now accept donors with diabetes, provided their condition is “well‐controlled”. However, glycemic control is not routinely assessed at donation, and the impact of donor diabetes on blood product quality remains unclear.
Elyn M. Rowe, Marcus Shew, Noor Ali‐Mohamad, Celina Phan, Mindy Goldman, Jason P. Acker, Dana V. Devine, James D. Johnson   +7 more
wiley   +1 more source

Linking dynamic cerebral autoregulation and inhibitory executive function: Role of modifiable behaviours

Experimental Physiology, EarlyView.
Abstract Dynamic cerebral autoregulation (dCA) stabilises cerebral blood flow (CBF) against rapid fluctuations in perfusion pressure and may serve as a key physiological mediator of cognitive function. Inhibitory executive function, a core domain essential for goal‐directed behaviour, is influenced by modifiable lifestyle factors such as physical ...
Hayato Tsukamoto, Damian M. Bailey
wiley   +1 more source

Therapeutic potential of okra (Abelmoschus esculentus) in dysglycaemia and metabolic dysfunction: A systematic review and meta‐analysis across the diabetes spectrum

Experimental Physiology, EarlyView.
Abstract The aim of this systematic review and meta‐analysis was to evaluate comprehensively the therapeutic potential of Abelmoschus esculentus (okra) supplementation across the diabetes spectrum of key metabolic risk factors. A search was conducted in PubMed, Scopus, Web of Science, EMBASE and the Cochrane Library, up to 23 July 2025, to identify ...
Ali Jafari, Helia Mardani, Mohammad Amin Karimi, MohammadHossein Sahami Gilan, Helia Hemmat, Fatemeh Shoja, Nooshin Enayati Soofi, Ghazaleh Eslamian   +7 more
wiley   +1 more source

Postexercise muscle oxygen uptake kinetics in older breast cancer survivors and healthy individuals: Association with myosteatosis

Experimental Physiology, EarlyView.
Abstract Reduced cardiorespiratory fitness is common among breast cancer survivors and, although traditionally attributed to cardiac dysfunction, might also be related to peripheral skeletal muscle abnormalities. We examined peak and submaximal plantar‐flexion exercise and recovery kinetics for lower‐leg oxygen uptake (V̇O2${\dot V_{{{\mathrm{O}}_2}}}$)
Nathan R. Weeldreyer, Thomas J. McMurtry, Stephen J. Foulkes, Amanda Shewman, Edith Pituskin, Rachel J. Skow, Richard B. Thompson, Justin Grenier, Deirdre E. O'Neill, Robert C. Welsh, Mark J. Haykowsky, Corey R. Tomczak   +11 more
wiley   +1 more source

Advances in cardiac devices and bioelectronics augmented with artificial intelligence

The Journal of Physiology, EarlyView.
Abstract figure legend Interfaces between the human heart, diagnostic bioelectronics, artificial intelligence, and clinical care. From left to right: Human heart and biosensor interface; representative waveforms of common diagnostic bioelectronic sensing modalities.
Charles Stark, Eric Rytkin, Andrei Alexandru Mircea, Igor R. Efimov   +3 more
wiley   +1 more source

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Oral Hypoglycemic Agents

Archives of Internal Medicine, 1960
In early 1942 while investigating the effect of isopropylthiodiazole (2254 RP) in typhoid fever, M. Janbon and co-workers in the Infectious Disease Clinic at Montpellier Medical School in France found that this sulfanilamide derivative produced signs and symptoms resembling hypoglycemia.
W G, TOMHAVE, W J, KUHL
exaly   +5 more sources

Oral Hypoglycemic Agents

New England Journal of Medicine, 1989
ORAL hypoglycemic agents are commonly prescribed drugs. In the United States they account for about 1 percent of all prescriptions.1 This review discusses the pharmacology, mechanisms of action, ef...
John A. Oates, Alastair J.J. Wood, John E. Gerich   +2 more
openaire   +4 more sources