Results 1 to 10 of about 15,559,661 (310)

Gut microbiota mediated hypoglycemic effect of Astragalus membranaceus polysaccharides in db/db mice. [PDF]

Front Pharmacol, 2022
Gut microbiota has been reported to be closely associated with Type-II diabetes. Restoration of disordered gut microbiota ecosystem has been developed into a therapeutic strategy and gradually applied on Type-II diabetes treatment with both western drugs
Song Q, Cheng SW, Li D, Cheng H, Lai YS, Han Q, Wu HY, Shaw PC, Zuo Z.   +8 more
europepmc   +2 more sources

Hypoglycemic Effect of Two Mexican Medicinal Plants. [PDF]

Plants (Basel), 2021
Type 2 diabetes is a worldwide prevalent disease that is due to a progressive loss of adequate β-cell insulin secretion, frequently against a background of insulin resistance. In Mexican traditional medicine, the therapeutic use of hypoglycemic plants to
Andrade-Cetto A, Espinoza-Hernández F, Mata-Torres G, Escandón-Rivera S.   +3 more
europepmc   +2 more sources

Hypoglycemic effect of the aqueous extract from Acalypha argomuelleri Briq. (Euphorbiaceae) 'Sweet stick' leaves in Rattus rattus var. albinus [version 3; peer review: 2 approved, 1 not approved] [PDF]

F1000Research
Introduction Diabetes mellitus (DM) is a chronic metabolic disease representing a global public health concern and is associated with severe complications such as cardiovascular and renal diseases.
Doyle Isabel Benel Fernández, Néstor Manuel Rodríguez Alayo, Berta Loja Herrera, Jorge Guillermo Morales Ramos, César Sánchez Marín, María Ema Soledad Mocarro Willis, Carolina Susana Loayza Estrada, Luis Felipe Pérez Medina   +7 more
doaj   +2 more sources

Optimization of Sweet Potato (Ipomoea batatas L.) Chlorogenic Acid Extraction Process and Hypoglycemic Effect Study [PDF]

Plants
Chlorogenic acid (CGA) is an active ingredient widely found in plants and has been shown to have potential blood-glucose-lowering effects. However, the research on the efficient extraction processes of CGA from sweet potatoes and its systematic ...
Xiaofei Wang, Jiayu Zhang, Chen Yang, Xiaohan Yu, Dan Tian, Mingli Han, Na Xiao   +6 more
doaj   +2 more sources

Ameliorative Hypoglycemic Effect of 1-DNJ via Structural Derivatization Followed by Assembly Into Selenized Nanovesicles [PDF]

International Journal of Nanomedicine
Shuxian Ruan,1,* Yanli Du,2,* Xianyuan Zhang,3 Xingwang Zhang,1 Hao Kang4 1Department of Pharmaceutics, College of Pharmacy, Jinan University, Guangzhou, People’s Republic of China; 2The First Affiliated Hospital of Jinan University, Guangzhou ...
Ruan S, Du Y, Zhang X, Zhang X, Kang H
doaj   +2 more sources

Phytochemical Composition and Acute Hypoglycemic Effect of Jefea lantanifolia (S. Schauer) Strother in Rats [PDF]

Plants
Jefea lantanifolia (S. Schauer) Strother is traditionally used in Hidalgo, Mexico, to manage type 2 diabetes (T2D). The aerial parts are prepared as an infusion and consumed throughout the day.
Fereshteh Safavi, Sonia M. Escandón-Rivera, Adolfo Andrade-Cetto, Daniel Rosas-Ramírez   +3 more
doaj   +2 more sources

Evaluation and Screening of Hypoglycemic Activity of Total Ginsenosides GBE-5 Fraction From Panax Ginseng Berry Based on UHPLC–MS Metabolomics

Frontiers in Nutrition, 2022
ObjectiveGinseng berry (GB) was the mature fruit of medicinal and edible herb, Panax ginseng C.A. Meyer, with significant hypoglycemic effect. Ginsenoside was the main hypoglycemic active component of GB. Evaluating and screening the effective components
Heyu Wang, Heyu Wang, Yu Tong, Anqi Wang, Ying Li, Bofan Lu, Hui Li, Lili Jiao, Wei Wu   +8 more
doaj   +1 more source

Synthesis and Pharmacological Evaluation of (+)-Usnic Acid Derivatives as Hypoglycemic Agents

Molbank, 2022
Usnic acid is produced by lichens and exhibits different biological properties, including hypoglycemic ones. However, this effect becomes noticeable only at relatively high doses, something that may lead to some adverse effects. The chemical modification
Sergey A. Borisov, Olga A. Luzina, Mikhail V. Khvostov, Tatiana G. Tolstikova, Nariman F. Salakhutdinov   +4 more
doaj   +1 more source

Active peptides with hypoglycemic effect obtained from hemp (Cannabis sativa L) protein through identification, molecular docking, and virtual screening.

Food Chemistry, 2023
Hemp (Cannabis sativa L) seeds are rich in proteins of high nutritional value, which makes the study of beneficial properties of hemp seed proteins and peptides, such as hypotensive and hypoglycemic effects, increasingly attractive.
Lei Cai, Shengwen Wu, Cheng-Gang Jia, Chun Cui, D. Sun-Waterhouse   +4 more
semanticscholar   +1 more source

Advances in Preparation, Biological Effect and Structure-activity Relationship of Hypoglycemic Peptides

Shipin gongye ke-ji, 2022
Diabetes is a serious global health problem, and its incidence rate has been increasing in recent years. Many drugs have been proven effective in the treatment of diabetes mellitus, but most of them have toxic side effects.
Tingxin ZHANG, Fuqiang LI, Nan ZHANG, Liping ZHU, Shigan YAN   +4 more
doaj   +1 more source