Results 41 to 50 of about 77,706 (265)

A review on the hypoglycemic effect of nigella sativa and thymoquinone

open access: yesSaudi Journal of Medicine and Medical Sciences, 2015
Nigella sativa (black seeds) is a very famous and popular herb used for centuries in many communities. N. sativa has been shown to possess therapeutic potential to many illnesses. Hypoglycemic effect of N.
Abdullah O Bamosa
doaj  

Optimization of Enzymatic Extraction Process and in Vitro Hypoglycemic Activity of Blackberry Polysaccharides

open access: yesShipin gongye ke-ji
To optimize the extraction process of blackberry polysaccharide and investigate its hypoglycemic activity in vitro, this study used enzymatic extraction to extract blackberry polysaccharide.
Chuanyu DUANMU   +8 more
doaj   +1 more source

Cassia grandis Lf nanodispersion is a hypoglycemic product with a potent α-glucosidase and pancreatic lipase inhibitor effect

open access: yesSaudi Pharmaceutical Journal, 2019
Purpose: This study aimed to evaluate the hypoglycemic effect, antioxidant, α-glucosidase and lipase inhibitory activity, and the cytotoxicity of the Cassia grandis nanodispersion (CgND).
Ariadna Lafourcade Prada   +7 more
doaj   +1 more source

Deformable Nanovesicle-Loaded Gel for Buccal Insulin Delivery

open access: yesPharmaceutics, 2022
Deformable nanovesicles (DNVs) have been widely used in oral mucosal delivery studies of biomolecular drugs. However, their development for oral mucosal preparations has been limited by their physical and chemical instability, the need for small oral ...
Yiyue Guo   +6 more
doaj   +1 more source

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

open access: yesAdvanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang   +7 more
wiley   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen   +7 more
wiley   +1 more source

The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John   +4 more
wiley   +1 more source

Hypoglycemic Effect of Intraspinal Glucose Injection

open access: yesExperimental Biology and Medicine, 1947
SummaryThe experimental increase of spinal fluid glucose caused rapid changes in blood sugar values, with a severe hypo-glycemia.
L, MARINELLI, V, GIUNTI
openaire   +2 more sources

Impact of Acute Functional Decline on Frailty and Mortality in Acutely Hospitalized Older Persons

open access: yesAGING MEDICINE, EarlyView.
Older persons with acute functional decline are often severely frail. Male sex, cognitive impairment, diabetes mellitus type 2, cancer, hearing impairment, and nursing home living increase the risk of severe frailty or death and should be considered when person‐centered care is planned for hospitalized older people.
Ali Vahedi   +5 more
wiley   +1 more source

Research progress in efficacy and mechanism of decreasing blood glucose by food nutrients

open access: yesLiang you shipin ke-ji, 2019
At present,the common food nutrients with hypoglycemic effect were divided into five categories:water-soluble dietary fiber,polysaccharides,flavonoids,saponins,trace elements.Animal experiments are mostly used to study the hypoglycemic effect of related ...
ZHANG Zong-ying   +3 more
doaj   +1 more source

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