Lactose Malabsorption and Lactose Intolerance in Children with Inflammatory Bowel Diseases [PDF]
Gastroenterology Research and Practice, 2019 Background. Insufficient vitamin D and calcium intake associated with the restricted intake of milk and dairy products can lead to poor health outcomes like malnutrition and abnormal bone mineralization.
Martyna Jasielska +1 more
doaj +3 more sources
13910C>T and 22018G>A LCT gene polymorphisms in diagnosing hypolactasia in children. [PDF]
United European Gastroenterol J, 2019 Background Primary lactose intolerance (PLI) is a gradual decrease of lactase activity that usually manifests at the age of 1–5 years. It has been proved that PLI is related to a single‐nucleotide polymorphism of the lactase (LCT) gene. Objective An evaluation was performed on the usefulness of genetic tests in detecting LCT 13910C>T and 22018G>A ...
Tomczonek-Moruś J +4 more
europepmc +4 more sources
Correlation between lactose absorption and the C/T-13910 and G/A-22018 mutations of the lactase-phlorizin hydrolase (LCT) gene in adult-type hypolactasia [PDF]
Brazilian Journal of Medical and Biological Research, 2007 The C/T-13910 mutation is the major factor responsible for the persistence of the lactase-phlorizin hydrolase (LCT) gene expression. Mutation G/A-22018 appears to be only in co-segregation with C/T-13910.
A.C. Bulhões +5 more
doaj +2 more sources
Perceived food intolerances can guide personalization of the FODMAP diet but not the choice of dietary intervention. [PDF]
JGH Open, 2023 JGH Open, Volume 7, Issue 11, Page 737-739, November 2023.
Rhys-Jones D, Yao CK, Gibson PR.
europepmc +2 more sources
Genetic Aspects of Adult-Type Hypolactasia
Journal of Gastrointestinal & Digestive System, 2016 Background and Objective: Lactose is a disaccharide sugar and is found in mammals milk and derivatives. Lactose intolerance is the inability to metabolize lactose, because of a lack of the required enzyme lactase in the digestive system. Genetically the physiological hypolactasia (primary LM) is associated with the LCT-13910 C/T and LCT-22018 G/A ...
Domenico Dell’Edera +4 more
openalex +2 more sources
Adult-type hypolactasia and lactose malabsorption in Poland.
Acta Biochimica Polonica, 2010 The available data on the incidence of lactose malabsorption are contradictory. Potential bias in random selection is a major drawback of studies performed to-date. Moreover, molecular analysis of polymorphism -13910 C>T upstream of the lactase (LCT) gene (NM_005915.4:c.1917+326C>T; rs4988235) has not been reported in those studies. Therefore, in
Edyta Mądry +7 more
openalex +4 more sources
Acta Cirúrgica Brasileira, 2013 PURPOSE: To analyze the usefulness of Quick Lactose Intolerance Test in relation to the genetic test based on LCT-13910C>T genotypes, previously validated for clinical practice, for primary hypolactasia/lactase-persistence diagnosis.
Rejane Mattar +3 more
doaj +1 more source
Phase IV noninferiority controlled randomized trial to evaluate the impact on diagnostic thinking and patient management and the test-retest reproducibility of the Gaxilose test for hypolactasia diagnosis. [PDF]
Medicine (Baltimore), 2018 Monsalve-Hernando C +13 more
europepmc +3 more sources
Assessment of Lactose-Free Diet on the Phalangeal Bone Mineral Status in Italian Adolescents Affected by Adult-Type Hypolactasia. [PDF]
Nutrients, 2018 Baldan A +8 more
europepmc +3 more sources