Results 31 to 40 of about 536 (156)

Lactose in drugs and lactose intolerance – realities and myths

Pediatria i Medycyna Rodzinna, 2018
Lactose intolerance is a set of clinical symptoms occurring after lactose intake, characterised by abdominal pain, bloating and diarrhoea. Adult-type hypolactasia is the most common cause of lactose intolerance and is associated with the physiological ...
Zygmunt Zdrojewicz, Kamila Zyskowska, Sylwia Wasiuk   +2 more
doaj   +1 more source

Peroxisome proliferator‐activated receptor gamma (PPARγ) regulates lactase expression and activity in the gut

EMBO Molecular Medicine, 2017
Lactase (LCT) deficiency affects approximately 75% of the world's adult population and may lead to lactose malabsorption and intolerance. Currently, the regulation of LCT gene expression remains poorly known.
Mathurin Fumery, Silvia Speca, Audrey Langlois, Anne‐Marie Davila, Caroline Dubuquoy, Marta Grauso, Anthony Martin Mena, Martin Figeac, Daniel Metzger, Christel Rousseaux, Jean‐Frederic Colombel, Laurent Dubuquoy, Pierre Desreumaux, Benjamin Bertin   +13 more
doaj   +1 more source

Lactose Hydrolysis in Milk and Dairy Whey Using Microbial β‐Galactosidases

Enzyme Research, Volume 2015, Issue 1, 2015., 2015
This work aimed at evaluating the influence of enzyme concentration, temperature, and reaction time in the lactose hydrolysis process in milk, cheese whey, and whey permeate, using two commercial β‐galactosidases of microbial origins. We used Aspergillus oryzae (at temperatures of 10 and 55°C) and Kluyveromyces lactis (at temperatures of 10 and 37°C) β‐
Michele Dutra Rosolen, Adriano Gennari, Giandra Volpato, Claucia Fernanda Volken de Souza, Toshihisa Ohshima   +4 more
wiley   +1 more source

Regulation of intestinal lactase in adult hypolactasia. [PDF]

Journal of Clinical Investigation, 1992
Relative deficiency of intestinal lactase activity during adulthood, adult hypolactasia, is a common condition worldwide. We studied the regulation of lactase-phlorizin hydrolase in normal and adult hypolactasic subjects by correlating transcript abundance in intestinal biopsies with relative synthetic rates for the protein in cultured intestinal ...
M, Lloyd, G, Mevissen, M, Fischer, W, Olsen, D, Goodspeed, M, Genini, W, Boll, G, Semenza, N, Mantei   +8 more
openaire   +2 more sources

Review article: Evidence‐based dietary management of inflammatory bowel disease

Alimentary Pharmacology &Therapeutics, Volume 60, Issue 9, Page 1215-1233, November 2024.
Summary Background Dietary management of patients with inflammatory bowel disease (IBD) involves more than defining a therapeutic diet. The profusion of ‘expert advice’ is not necessarily built on evidence. Aims To provide evidence‐based guidance on all clinically relevant aspects of nutritional and dietary management of patients with IBD.
Peter R. Gibson, C. K. Yao, Emma P. Halmos   +2 more
wiley   +1 more source

Relation of the disaccharidases in the small intestine of the rat to the degree of experimentally induced iron-deficiency anemia

Brazilian Journal of Medical and Biological Research, 2000
Hypolactasia associated with severe iron-deficiency anemia has been reported in several studies. The objective of the present study was to determine whether hypolactasia is associated with the degree and duration of iron-deficiency anemia.
M.R. Vieira, L.C. Galvão, M.I.M. Fernandes   +2 more
doaj   +1 more source

Lactose Malabsorption Testing in Daily Clinical Practice: A Critical Retrospective Analysis and Comparison of the Hydrogen/Methane Breath Test and Genetic Test (C/T−13910 Polymorphism) Results

Gastroenterology Research and Practice, Volume 2014, Issue 1, 2014., 2014
The aim of this study was to establish a retrospective evaluation and comparison of the hydrogen/methane (H2/CH4) breath test and genetic test (C/T−13910 polymorphism) results in lactose malabsorption testing. In total 263 consecutive patients with suspected lactose malabsorption were included in this study.
Dietmar Enko, Erwin Rezanka, Robert Stolba, Gabriele Halwachs-Baumann, Peter James Whorwell   +4 more
wiley   +1 more source

Effects of Exogenous Lactase Administration on Hydrogen Breath Excretion and Intestinal Symptoms in Patients Presenting Lactose Malabsorption and Intolerance

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
Objective. To establish whether supplementation with a standard oral dose of Beta‐Galactosidase affects hydrogen breath excretion in patients presenting with lactose malabsorption. Methods. Ninety‐six consecutive patients positive to H2 Lactose Breath Test were enrolled.
Ivan Ibba, Agnese Gilli, Maria Francesca Boi, Paolo Usai, Enrico Compalati   +4 more
wiley   +1 more source

Genetic Aspects of Adult-Type Hypolactasia

Journal of Gastrointestinal & Digestive System, 2016
Background and Objective: Lactose is a disaccharide sugar and is found in mammals milk and derivatives. Lactose intolerance is the inability to metabolize lactose, because of a lack of the required enzyme lactase in the digestive system. Genetically the physiological hypolactasia (primary LM) is associated with the LCT-13910 C/T and LCT-22018 G/A ...
DellEdera D, Nicoletti FP, D Apice MR, Allegretti A, Epifania AA   +4 more
openaire   +1 more source

Comparison of Quick Lactose Intolerance Test in duodenal biopsies of dyspeptic patients with single nucleotide polymorphism LCT-13910C>T associated with primary hypolactasia/lactase-persistence Comparação do Teste Quick de Intolerância à Lactose em biópsias duodenais de pacientes dispépticos com polimorfismo de nucleotídeo único LCT-13910C>T associado com hipolactasia primária/lactase persistente

Acta Cirúrgica Brasileira, 2013
PURPOSE: To analyze the usefulness of Quick Lactose Intolerance Test in relation to the genetic test based on LCT-13910C>T genotypes, previously validated for clinical practice, for primary hypolactasia/lactase-persistence diagnosis.
Rejane Mattar, Anibal Basile-Filho, Rafael Kemp, José Sebastião dos Santos   +3 more
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