Results 41 to 50 of about 767 (179)
EMBO Molecular Medicine, 2017 Lactase (LCT) deficiency affects approximately 75% of the world's adult population and may lead to lactose malabsorption and intolerance. Currently, the regulation of LCT gene expression remains poorly known.
Mathurin Fumery +13 more
doaj +1 more source
Review article: Evidence‐based dietary management of inflammatory bowel disease
Alimentary Pharmacology &Therapeutics, Volume 60, Issue 9, Page 1215-1233, November 2024.Summary Background Dietary management of patients with inflammatory bowel disease (IBD) involves more than defining a therapeutic diet. The profusion of ‘expert advice’ is not necessarily built on evidence. Aims To provide evidence‐based guidance on all clinically relevant aspects of nutritional and dietary management of patients with IBD.
Peter R. Gibson +2 more
wiley +1 more source
, 2007 Recently, the C/T-13910 polymorphism on chromosome 2q21 in North-European populations has been found completely associated with lactase activity and its genetic typing proposed as first-stage screening test for adult hypolactasia.
LORIGA F +14 more
core +1 more source
Gastroenterology Research and Practice, Volume 2014, Issue 1, 2014., 2014 The aim of this study was to establish a retrospective evaluation and comparison of the hydrogen/methane (H2/CH4) breath test and genetic test (C/T−13910 polymorphism) results in lactose malabsorption testing. In total 263 consecutive patients with suspected lactose malabsorption were included in this study.
Dietmar Enko +4 more
wiley +1 more source
, 2015 Aims. Adult-type hypolactasia (ATH) is the genetically determined most common cause of milk intolerance in children, adolescents and adults and the most common enzyme deficiency in humans.
Роговик, Н.В. +4 more
core +2 more sources
Brazilian Journal of Medical and Biological Research, 2000 Hypolactasia associated with severe iron-deficiency anemia has been reported in several studies. The objective of the present study was to determine whether hypolactasia is associated with the degree and duration of iron-deficiency anemia.
M.R. Vieira +2 more
doaj +1 more source
BioMed Research International, Volume 2014, Issue 1, 2014., 2014 Objective. To establish whether supplementation with a standard oral dose of Beta‐Galactosidase affects hydrogen breath excretion in patients presenting with lactose malabsorption. Methods. Ninety‐six consecutive patients positive to H2 Lactose Breath Test were enrolled.
Ivan Ibba +4 more
wiley +1 more source
Regulation of intestinal lactase in adult hypolactasia. [PDF]
Journal of Clinical Investigation, 1992 Relative deficiency of intestinal lactase activity during adulthood, adult hypolactasia, is a common condition worldwide. We studied the regulation of lactase-phlorizin hydrolase in normal and adult hypolactasic subjects by correlating transcript abundance in intestinal biopsies with relative synthetic rates for the protein in cultured intestinal ...
M, Lloyd +8 more
openaire +2 more sources
Use of genetic testing for hypolactasia trait in the North Denmark Region
, 2020 Objective: Lactose intolerance (LI) may be considered in patients with unspecific gastrointestinal symptoms, but there is no clear consensus on when and how to diagnose the disorder.
Mørk, Morten; id_orcid +5 more
core +1 more source
Hypolactasia is associated with insulin resistance in nonalcoholic steatohepatitis
World Journal of Hepatology, 2016 To assess lactase gene (LCT)-13910C>T polymorphisms in Brazilian non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) patients in comparison with healthy controls.This was a transverse observational clinical study with NAFLD patients who were followed at the Hepatology Outpatient Unit of the Hospital das Clínicas, São Paulo,
Daniel Ferraz, de Campos Mazo +10 more
openaire +2 more sources