Results 41 to 50 of about 544 (156)

Hypolactasia is associated with insulin resistance in nonalcoholic steatohepatitis

World Journal of Hepatology, 2016
To assess lactase gene (LCT)-13910C>T polymorphisms in Brazilian non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) patients in comparison with healthy controls.This was a transverse observational clinical study with NAFLD patients who were followed at the Hepatology Outpatient Unit of the Hospital das Clínicas, São Paulo,
Daniel Ferraz, de Campos Mazo, Rejane, Mattar, José Tadeu, Stefano, Joyce Matie Kinoshita, da Silva-Etto, Márcio Augusto, Diniz, Sebastião Mauro Bezerra, Duarte, Fabíola, Rabelo, Rodrigo Vieira Costa, Lima, Priscila Brizolla, de Campos, Flair José, Carrilho, Claudia P, Oliveira   +10 more
openaire   +2 more sources

Розповсюдження генетично детермінованої гіполактазії дорослого типу у хворих на муковісцидоз, гомозигот за мутацією p.Phe508del

Фактори експериментальної еволюції організмів, 2015
Aims. Adult-type hypolactasia (ATH) is the genetically determined most common cause of milk intolerance in children, adolescents and adults and the most common enzyme deficiency in humans.
М. Я. Тиркус, Г. В. Макух, Л. Й. Бобер, Н. В. Роговик, О. З. Гнатейко   +4 more
doaj  

Comparison of Quick Lactose Intolerance Test in duodenal biopsies of dyspeptic patients with single nucleotide polymorphism LCT-13910C>T associated with primary hypolactasia/lactase-persistence Comparação do Teste Quick de Intolerância à Lactose em biópsias duodenais de pacientes dispépticos com polimorfismo de nucleotídeo único LCT-13910C>T associado com hipolactasia primária/lactase persistente

Acta Cirúrgica Brasileira, 2013
PURPOSE: To analyze the usefulness of Quick Lactose Intolerance Test in relation to the genetic test based on LCT-13910C>T genotypes, previously validated for clinical practice, for primary hypolactasia/lactase-persistence diagnosis.
Rejane Mattar, Anibal Basile-Filho, Rafael Kemp, José Sebastião dos Santos   +3 more
doaj  

Genetic Aspects of Adult-Type Hypolactasia

Journal of Gastrointestinal & Digestive System, 2016
Background and Objective: Lactose is a disaccharide sugar and is found in mammals milk and derivatives. Lactose intolerance is the inability to metabolize lactose, because of a lack of the required enzyme lactase in the digestive system. Genetically the physiological hypolactasia (primary LM) is associated with the LCT-13910 C/T and LCT-22018 G/A ...
DellEdera D, Nicoletti FP, D Apice MR, Allegretti A, Epifania AA   +4 more
openaire   +1 more source

Correlation between lactose absorption and the C/T-13910 and G/A-22018 mutations of the lactase-phlorizin hydrolase (LCT) gene in adult-type hypolactasia

Brazilian Journal of Medical and Biological Research, 2007
The C/T-13910 mutation is the major factor responsible for the persistence of the lactase-phlorizin hydrolase (LCT) gene expression. Mutation G/A-22018 appears to be only in co-segregation with C/T-13910.
A.C. Bulhões, H.A.S. Goldani, F.S. Oliveira, U.S. Matte, R.B. Mazzuca, T.R. Silveira   +5 more
doaj   +1 more source

Morphological method for the diagnosis of human adult type hypolactasia. [PDF]

Gut, 1994
The primary adult type hypolactasia is the most common form of genetically determined disaccharidase deficiency. This study examined a large and homogeneous population of the south of Italy: surgical biopsy specimens of proximal jejunum from 178 adult subjects have been assayed for disaccharidase activities; the expression of lactase protein and ...
MAIURI, Luigi, ROSSI M, RAIA V, PAPARO F, COLETTA S, MAZZEO F, BREGLIA A, AURICCHIO S.   +7 more
openaire   +4 more sources

Host genetic variation and its microbiome interactions within the Human Microbiome Project

Genome Medicine, 2018
Background Despite the increasing recognition that microbial communities within the human body are linked to health, we have an incomplete understanding of the environmental and molecular interactions that shape the composition of these communities ...
Raivo Kolde, Eric A. Franzosa, Gholamali Rahnavard, Andrew Brantley Hall, Hera Vlamakis, Christine Stevens, Mark J. Daly, Ramnik J. Xavier, Curtis Huttenhower   +8 more
doaj   +1 more source

Rotavirus infection in children with different variants allelic polymorphism C> T 13910 gene LCT = Перебіг ротавірусної інфекції у дітей з різними варіантами алельного поліморфізму С >Т 13910 гена лактази

Journal of Education, Health and Sport, 2016
Nezgoda I., Naumenko O. Rotavirus infection in children with different variants allelic polymorphism C> T 13910 gene LCT = Перебіг ротавірусної інфекції у дітей з різними варіантами алельного поліморфізму С >Т 13910 гена лактази.
I. Nezgoda, O. Naumenko
doaj   +3 more sources

ROLE OF BREASTFEEDING IN PREVENTING LONG-TERM METABOLIC DISORDERS: REVIEW

Педиатрическая фармакология, 2015
The literature review is dedicated to the preventive role of breastfeeding in preserving long-term health of individuals and the population in whole.
I. A. Belyaeva, L. S. Namazova-Baranova, T. V. Turti, E. P. Bombardirova, M. D. Mitish, T. V. Potekhina   +5 more
doaj   +1 more source

Foodomics based on synergy principles for children with lactose intolerance

Новые технологии
. Introduction. Food intolerance is a significant modern demographic problem, the main cause of which is a deficiency of digestive enzymes. Hypolactasia, or lactose deficiency, is a condition common to people of all ages and requires dietary adjustments ...
V. V. Bychenkova, I. A. Karmanov
doaj   +1 more source