Results 21 to 30 of about 767 (179)

Proposed mechanism for the selection of lactase persistence in childhood

BioEssays, Volume 45, Issue 7, July 2023., 2023
In cultures where raw milk is traditionally consumed, the progressive increase in lactose maldigestion in early childhood combined with the substantial milk energy gap between digesters and maldigesters in this age group represents a strong mechanism for the selection of lactase persistence.
Alexandre Fabre, Anne Fabre, Céline Bon, Paul Guerry, Laure Segurel   +4 more
wiley   +1 more source

Improved Gold Nanoprobes for Detection of Single Nucleotide Polymorphisms: The Influence of Size

Particle &Particle Systems Characterization, Volume 39, Issue 12, December 2022., 2022
Unique plasmonic properties of gold nanoparticles (AuNPs) are used for detection of a single nucleotide polymorphism related to lactose intolerance. Assays based on 20 nm and 35 nm AuNPs functionalized with specific oligonucleotide probes are compared and found that 35 nm AuNPs allow a reduction of 80% and 48% in the amount of gold and oligonucleotide ...
Maria Enea, Miguel Peixoto de Almeida, André Dias, Beatriz Ferreira, Carlos Bernardes, Orfeu Flores, Eulália Pereira, Ricardo Franco   +7 more
wiley   +1 more source

European guideline on indications, performance, and clinical impact of hydrogen and methane breath tests in adult and pediatric patients: European Association for Gastroenterology, Endoscopy and Nutrition, European Society of Neurogastroenterology and Motility, and European Society for Paediatric Gastroenterology Hepatology and Nutrition consensus

United European Gastroenterology Journal, Volume 10, Issue 1, Page 15-40, February 2022., 2022
Abstract Introduction Measurement of breath hydrogen (H2) and methane (CH4) excretion after ingestion of test‐carbohydrates is used for different diagnostic purposes. There is a lack of standardization among centers performing these tests and this, together with recent technical developments and evidence from clinical studies, highlight the need for a ...
Heinz F. Hammer, Mark R. Fox, Jutta Keller, Silvia Salvatore, Guido Basilisco, Johann Hammer, Loris Lopetuso, Marc Benninga, Osvaldo Borrelli, Dan Dumitrascu, Bruno Hauser, Laszlo Herszenyi, Radislav Nakov, Daniel Pohl, Nikhil Thapar, Marc Sonyi, European H2‐CH4‐breath test group   +16 more
wiley   +1 more source

The effect of yogurt fortified with Lactobacillus acidophilus and Bifidobacterium sp. probiotic in patients with lactose intolerance

Food Science &Nutrition, Volume 9, Issue 3, Page 1704-1711, March 2021., 2021
Our findings revealed that probiotic yogurt fortified with L. acidophilus and Bifidobacterium sp. could safely and effectively decrease lactose intolerance symptoms and HBT, so our probiotic can be recommended as a treatment of choice in lactose intolerance patients.
Seyed Jalil Masoumi, Davood Mehrabani, Mehdi Saberifiroozi, Mohammad Reza Fattahi, Fariba Moradi, Masoud Najafi   +5 more
wiley   +1 more source

Very low frequency of the lactase persistence allele LCT-13910T in the Armenian population

Annals of Human Biology, 2022
Primary lactose malabsorption is characterised by a down-regulation of lactase activity after weaning and inability to digest lactose in adulthood. It has been suggested that the historical introduction of dairying led to a positive selection for lactase
Stefan Németh, Gernot Kriegshäuser, Kristine Hovhannesyan, Hasmik Hayrapetyan, Christian Oberkanins, Tamara Sarkisian   +5 more
doaj   +1 more source

Phase IV noninferiority controlled randomized trial to evaluate the impact on diagnostic thinking and patient management and the test-retest reproducibility of the Gaxilose test for hypolactasia diagnosis. [PDF]

Medicine (Baltimore), 2018
The diagnostic accuracy of the Gaxilose test (GT) for hypolactasia diagnosis has already been proved. The objectives of this clinical trial were to demonstrate the noninferiority of the GT compared to the hydrogen breath test (HBT) on the impact on ...
Monsalve-Hernando C, Crespo L, Ferreiro B, Martín V, Aldeguer X, Opio V, Fernández-Gil PL, Gaspar MJ, Romero E, Lara C, Santander C, Torrealba L, Savescu T, Hermida C.   +13 more
europepmc   +2 more sources

Polymorphism of the genetic determinants of bone mineral metabolism in various groups of the Komi people [PDF]

Вестник археологии, антропологии и этнографии, 2021
The subject of the study is autochthonous population of the Northern and Middle Cis-Urals: Komi-Permyaks, Komi (Zyryans), and Komi-Izhems. The aim of the study is to compare the population frequencies of the LCT (rs4988235) and VDR (FokI rs2228570 and ...
Kozlov A.I.
doaj   +1 more source

The role of a combined probiotic in the treatment of lactase deficiency

Терапевтический архив, 2021
Aim. To study the effectiveness of the combined probiotic Bifiform and the enzyme lactase in the treatment of secondary lactase deficiency (SLD). Materials and methods.
Irina N. Ruchkina, Nina A. Fadeeva
doaj   +1 more source

Digestive enzyme expression in the large intestine of children with short bowel syndrome in a late stage of adaptation

The FASEB Journal, Volume 34, Issue 3, Page 3983-3995, March 2020., 2020
Abstract Background and aims: Intestinal adaptation in short bowel syndrome (SBS) includes morphologic processes and functional mechanisms. This study investigated whether digestive enzyme expression in the duodenum and colon is upregulated in SBS patients. Method: Sucrase‐isomaltase (SI), lactase‐phlorizin hydrolase (LPH), and neutral Aminopeptidase N
Jan de Laffolie, Diana Sheridan, Konrad Reinshagen, Lucas Wessel, Christian Zimmermann, Sebastian Stricker, Markus M. Lerch, Markus Weigel, Torsten Hain, Eugen Domann, Silvia Rudloff, Buford L. Nichols, Hassan Y. Naim, Klaus‐Peter Zimmer   +13 more
wiley   +1 more source

Genetiс aspects of lactase persistence in different ethnic groups

Фактори експериментальної еволюції організмів, 2020
Aim. The aim of this study was evaluation of the genetic aspects of lactase persistence (LP) in persons from different ethnic groups. Methods. Genealogical and medical information was collected about Ukrainian, Indian, Nigerian, Israel, Egypt, Palestine,
V. V. Borozenets, V. O. Babalian, O. M. Fedota   +2 more
doaj   +1 more source