Background Adult-type hypolactasia, the physiological decline of lactase some time after weaning, was previously associated with the LCT -13910C>T polymorphism worldwide except in Africa.
Silva Joyce MK +5 more
doaj +2 more sources
Diagnosis of adult-type hypolactasia/lactase persistence: genotyping of single nucleotide polymorphism (SNP C/T-13910) is not consistent with breath test in Colombian Caribbean population [PDF]
CONTEXT: Genotyping of single nucleotide polymorphism (SNP C/T-13910) located upstream of the lactase gene is used to determine adult-type hypolactasia/lactase persistence in North-European Caucasian subjects.
Evelyn Mendoza Torres +3 more
doaj +2 more sources
Analytical Validation of a New Enzymatic and Automatable Method for d-Xylose Measurement in Human Urine Samples. [PDF]
Hypolactasia, or intestinal lactase deficiency, affects more than half of the world population. Currently, xylose quantification in urine after gaxilose oral administration for the noninvasive diagnosis of hypolactasia is performed with the hand‐operated nonautomatable phloroglucinol reaction.
Sánchez-Moreno I +11 more
europepmc +6 more sources
Background Primary hypolactasia is a common condition where a reduced lactase activity in the intestinal mucosa is present. The presence of abdominal symptoms due to poor absorption of lactose, which are present in some cases, is a characteristic of ...
Carlos Fernando de Magalhães FRANCESCONI +7 more
doaj +2 more sources
Correlation between lactose absorption and the C/T-13910 and G/A-22018 mutations of the lactase-phlorizin hydrolase (LCT) gene in adult-type hypolactasia [PDF]
The C/T-13910 mutation is the major factor responsible for the persistence of the lactase-phlorizin hydrolase (LCT) gene expression. Mutation G/A-22018 appears to be only in co-segregation with C/T-13910.
A.C. Bulhões +5 more
doaj +3 more sources
PURPOSE: To analyze the usefulness of Quick Lactose Intolerance Test in relation to the genetic test based on LCT-13910C>T genotypes, previously validated for clinical practice, for primary hypolactasia/lactase-persistence diagnosis.
Rejane Mattar +3 more
doaj +1 more source
Perceived food intolerances can guide personalization of the FODMAP diet but not the choice of dietary intervention. [PDF]
JGH Open, Volume 7, Issue 11, Page 737-739, November 2023.
Rhys-Jones D, Yao CK, Gibson PR.
europepmc +2 more sources
A felnőttkori hypolactasia születésikohorsz-vizsgálata [PDF]
Abstract: Introduction and aim: To assess the prevalence of lactase gene promoter C/T13910 phenotypes in patients with lactose intolerance symptoms and to analyze the birth-cohort phenomenon in lactose-intolerant patients. Method: 1266 patients consulted between 2010 and 2017 were enrolled.
Buzás, György Miklós +1 more
openaire +2 more sources
13910C>T and 22018G>A LCT gene polymorphisms in diagnosing hypolactasia in children. [PDF]
Background Primary lactose intolerance (PLI) is a gradual decrease of lactase activity that usually manifests at the age of 1–5 years. It has been proved that PLI is related to a single‐nucleotide polymorphism of the lactase (LCT) gene. Objective An evaluation was performed on the usefulness of genetic tests in detecting LCT 13910C>T and 22018G>A ...
Tomczonek-Moruś J +4 more
europepmc +2 more sources
A 5‐week novel Monash Pouch diet was well tolerated and had high patient acceptability. The diet achieved a reduction in protein versus carbohydrate fermentative activity and deserves further investigation in a well‐powered larger randomized‐controlled trial.
Zaid S Ardalan +8 more
wiley +1 more source

