Several different lactase persistence associated alleles and high diversity of the lactase gene in the admixed Brazilian population. [PDF]
PLoS ONE, 2012 Adult-type hypolactasia is a common phenotype caused by the lactase enzyme deficiency. The -13910 C>T polymorphism, located 14 Kb upstream of the lactase gene (LCT) in the MCM6 gene was associated with lactase persistence (LP) in Europeans.
Deise C Friedrich +3 more
doaj +1 more source
Development of a new method for D-xylose detection and quantification in urine, based on the use of recombinant xylose dehydrogenase from Caulobacter crescentus. [PDF]
, 2016 The gene xylB from Caulobacter crescentus has been cloned and expressed in Escherichia coli providing a high yield of xylose dehydrogenase (XylB) production and excellent purity (97%).
Fernández-Mayoralas, Alfonso +3 more
core +1 more source
Genetic Aspects of Adult-Type Hypolactasia
Journal of Gastrointestinal & Digestive System, 2016 Background and Objective: Lactose is a disaccharide sugar and is found in mammals milk and derivatives. Lactose intolerance is the inability to metabolize lactose, because of a lack of the required enzyme lactase in the digestive system. Genetically the physiological hypolactasia (primary LM) is associated with the LCT-13910 C/T and LCT-22018 G/A ...
Domenico Dell’Edera +4 more
openalex +3 more sources
Measuring lactase enzymatic activity in the teaching lab [PDF]
, 2018 Understanding how enzymes work, and relating this to real life examples, is critical to a wide range of undergraduate degrees in the biological and biomedical sciences.
Cottrell, Graeme +5 more
core +2 more sources
Comparative metabolomics in primates reveals the effects of diet and gene regulatory variation on metabolic divergence. [PDF]
, 2014 Human diets differ from those of non-human primates. Among few obvious differences, humans consume more meat than most non-human primates and regularly cook their food.
Blekhman, Ran +5 more
core +2 more sources
Association of the rs4988235 in the lactase gene with obesity and its modulation by dairy products in a Mediterranean population [PDF]
, 2011 The -13910C>T polymorphism (rs4988235) upstream from the lactase (LCT) gene, strongly associated with lactase persistence (LP) in Europeans, is emerging as a new candidate for obesity. We aimed to analyze the association of this polymorphism with obesity-
Arregui, María +9 more
core +2 more sources
Molecular Nutrition &Food Research, Volume 63, Issue 21, November 2019., 2019 Despite numerous examples of interindividual variability in the processing of food by the human gastrointestinal tract, the knowledge on this topic, as illustrated for polymorphisms in mineral absorption, remains fragmented. The GutSelf review sets the base for motivating future research specifically addressing the issue of the interindividual ...
Barbara Walther +14 more
wiley +1 more source
Вавиловский журнал генетики и селекции, 2017 Retention of lactase activity in adulthood (lactase persistence) is one of the most important adaptive traits for human populations that consume fresh milk from domestic animals.
I. V. Pilipenko +4 more
doaj +1 more source
Association of lactase persistence genotype with milk consumption, obesity and blood pressure:a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort with a systematic review and meta-analysis. [PDF]
, 2016 Background: Milk intake has been associated with lower blood pressure (BP) in observational studies, and randomized controlled trials suggested that milk-derived tripeptides have BP-lowering effects.
Davey Smith, George +4 more
core +1 more source
DIGESTIVE DISORDERS IN PREMATURELY BORN CHILDREN
Вопросы современной педиатрии, 2012 The article contains data on functional digestive disorders in newborns, mainly on the problem of lactase (disaccharidase) insufficiency. The information on the prevalence of this condition, modern classification of hypolactasia, diagnostic techniques ...
I. A. Belyaeva +2 more
doaj +1 more source