Results 31 to 40 of about 3,173,890 (267)

Effect of Early Initiation of Evolocumab on Lipoprotein(a) in Patients with Acute Myocardial Infarction: Sub-Analysis of a Randomized Controlled Trial

Journal of Cardiovascular Development and Disease, 2022
Elevated circulating lipoprotein(a) levels are associated with an increased risk of cardiovascular events. We reported that early initiation of evolocumab, a proprotein convertase subtilisin/kexin type 9 inhibitor, in addition to a statin substantially ...
Tomoaki Okada, Toru Miyoshi, Masayuki Doi, Kazumasa Nosaka, Ryu Tsushima, Satoko Ugawa, Wataru Takagi, Masahiro Sogo, Masahiko Takahashi, Hiroshi Ito   +9 more
doaj   +1 more source

Structural, Spectroscopic, and Docking Analysis of N,O-Donor Ligand Metal Complex Nanoparticles With Hypolipidemic Effects via Lipoprotein Lipase Activation in High-Fat Diet Mice. [PDF]

Chem Biodivers
Hypolipidemic influence of CETZ.2HCl‐(H1‐antihistamine) metal‐complexes on “C57Bl/6‐mice” fed high‐fat‐diet. ABSTRACT New Cd(II), Zn(II), and Cu(II) chelates with cetirizine.2HCl (CETZ.2HCl) in incidence of 1,10 phenanthroline monohydrate (Phen.H2O) were synthesized in search of new biologically active compounds.
Abd El-Hamid SM, Aziz SW, Mohamed AA, El-Gedamy MS, Salem AE, Mohammed SF, Zordok WA, Sofo A, Sabry MA, Sadeek SA, Elshafie HS.   +10 more
europepmc   +2 more sources

PCSK9 Antagonists: Clinical Efficacy and Main Trends in the Development of New Medicines

Безопасность и риск фармакотерапии, 2023
Scientific relevance. Cardiovascular diseases (CVD) are the leading cause of death worldwide. Dyslipidemia, as the pathophysiological basis of atherosclerosis, is the most important cause of CVD.
A. A. Nekipelova, R. N. Alyautdin
doaj   +1 more source

Medicinal plants with cholesterol-lowering effect marketed in the Buenos Aires-La Plata conurbation, Argentina : An Urban Ethnobotany study [PDF]

, 2015
Fil: Hurrell, Julio Alberto. Laboratorio de Etnobotánica y Botánica Aplicada (LEBA). Facultad de Ciencias Naturales y Museo. Universidad Nacional de La Plata; ArgentinaFil: Puentes, Jeremías P..
Arenas, Patricia Marta, Hurrell, Julio Alberto, Puentes, Jeremías P.   +2 more
core   +2 more sources

The effect of 12 weeks Anethum graveolens (dill) on metabolic markers in patients with metabolic syndrome; A randomized double blind controlled trial [PDF]

, 2012
Background: The clustering of metabolic abnormalities defined as metabolic syndrome is now both a public health and a clinical problem .While interest in herbal medicine has greatly increased, lack of human evidence to support efficacies shown in animals
Hasani-Ranjbar, S., Keshtkar, A., Larijani, B., Mansouri, M., Nayebi, N., Taheri, E.   +5 more
core   +3 more sources

Microwave-Assisted Synthesis, Biological Activity Evaluation, Molecular Docking, and ADMET Studies of Some Novel Pyrrolo [2,3-b] Pyrrole Derivatives

Molecules, 2022
Novel pyrrolo [2,3-b] pyrrole derivatives were synthesized and their hypolipidemic activity was assessed in hyperlipidemic rats. The chemical structures of the new derivatives were confirmed through spectral analysis.
Moumen S. Kamel, Amany Belal, Moustafa O. Aboelez, E. Kh. Shokr, H. Abdel-Ghany, Hany S. Mansour, Ahmed M. Shawky, Mahmoud Abd El Aleem Ali Ali El-Remaily   +7 more
doaj   +1 more source

Sustainable Synthesis of the Naturally Hypolipidemic Agent α-Asarone [PDF]

Synthetic Communications, 2015
:A short and practical preparation of α-asarone was developed using the inexpensive methylisoeugenol as a starting material. The utilization of a sequence of tribromination, debromination and copper-mediated aromatic substitution enabled the stereoselective formation of only the E isomer of α-asarone in good yield.
Alejandro Camacho-Dávila, Gerardo Zaragoza-Galán, David Chávez-Flores, Víctor H. Ramos-Sánchez   +3 more
openaire   +2 more sources

Effects of phthalic acid esters on the liver and thyroid [PDF]

, 1986
The effects, over periods from 3 days to 9 months of administration, of diets containing di-2-ethylhexyl phthalate are very similar to those observed in rats administered diets containing hypolipidemic drugs such as clofibrate.
A Mann, A Nunn, Bergmeyer H. U., Braveman L. E., Carpenter C. P., Collins W. T., Committee of Principal Investigators, D Chescoe, F E Mitchell, Ganning A., Garvin P. J., Gray T., Horic S., J W Bridges, Johnston I. R., Omura T., Oppenheimer J. H, P Grasso, Price S. C., R H Hinton, Reddy J. K., S C Price, Sex, Svoboda D. J.   +23 more
core   +2 more sources

Doxorubicin Selectively Inhibits Brain versus Atrial Natriuretic Peptide Gene Expression in Cultured Neonatal Rat Myocytes [PDF]

, 1999
Doxorubicin is an antineoplastic agent with significant cardiotoxicity. We examined the effects of this agent on the expression of the natriuretic peptide (NP) genes in cultured neonatal rat atrial myocytes.
Chen, Songcang, Garami, Miklós, Gardner, D. G.   +2 more
core   +1 more source

An overview of anti-diabetic plants used in Gabon: Pharmacology and Toxicology [PDF]

, 2018
© 2017 Elsevier B.V. All rights reserved.Ethnopharmacological relevance: The management of diabetes mellitus management in African communities, especially in Gabon, is not well established as more than 60% of population rely on traditional treatments as ...
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core   +3 more sources