Results 31 to 40 of about 19,792 (277)

MODELING OF MICE AS TEST ANIMALS FOR A PRECLINICAL STUDY OF HYPOLIPIDEMIC AGENTS

Jurnal Farmasi Sains dan Praktis, 2023
Animal models suitable for preclinical research are necessary for the discovery of hypolipidemic agents. Various publications have presented alternative dyslipidemia animal models, but identifying a feasible and stable method would serve as a solid ...
Setiyo Budi Santoso, Widarika Santi Hapsari, Renny Setyowati   +2 more
doaj   +1 more source

Study on the influence of 7-β-hydroxy-γ-aryloxypropylxanthinyl-8-thioalkanic acid derivatives on the lipid metabolism in experiment

Zaporožskij Medicinskij Žurnal, 2021
Statin side effects are not a rare occurrence, in particular dyspeptic disorders, insomnia, headache, skin erythema, rash are often noted. All of this determines scientists to find new effective and low-toxic hypolipidemic agents.
I. M. Bilai, M. I. Romanenko, D. H. Ivanchenko   +2 more
doaj   +1 more source

Doxorubicin Selectively Inhibits Brain versus Atrial Natriuretic Peptide Gene Expression in Cultured Neonatal Rat Myocytes [PDF]

, 1999
Doxorubicin is an antineoplastic agent with significant cardiotoxicity. We examined the effects of this agent on the expression of the natriuretic peptide (NP) genes in cultured neonatal rat atrial myocytes.
Chen, Songcang, Garami, Miklós, Gardner, D. G.   +2 more
core   +1 more source

Comparative analysis of the use of lipid modifying agents in the Republic of Serbia and Nordic countries in the period 2015-2017 [PDF]

Hospital Pharmacology, 2020
Introduction: Cardiovascular diseases are the leading cause of death both in Serbia and in the rest of the world. It has been shown that as many as 80% of them are preventable.
Martić Nikola B., Zečević Dragan D., Đurđević Milena V., Milijašević Dragana S., Tomić Nataša Z., Lalić-Popović Mladena N., Todorović Nemanja B., Medin Danilo V., Mićanović Branimir B., Milijašević Boris Ž.   +9 more
doaj  

Bempedoic acid and its role in contemporary management of hyperlipidemia in atherosclerosis

Annals of Medicine, 2022
Atherosclerotic heart disease is the leading cause of mortality and morbidity in the USA. Low density lipoprotein (LDL) has been the target for many hypolipidemic agents to modify atherosclerotic risk.
Ramyashree Tummala, Manasvi Gupta, Arvind Reddy Devanabanda, Dhrubajyoti Bandyopadhyay, Wilbert S. Aronow, Kausik K. Ray, Mamas Mamas, Raktim K. Ghosh   +7 more
doaj   +1 more source

Lactucin & Lactucopicrin ameliorates FFA-induced steatosis in HepG2 cells via modulating lipid metabolism

Journal of Pharmacological Sciences, 2022
Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases, and there are no effective drugs available so far. Lactucin and Lactucopicrin belong to sesquiterpene lactones and are extracted from Cichorium glandulosum Boiss.
Yilizere Aibaidula, Mutalifu Aimaiti, Huiwen Tan, Bingting Chen, Jian Yang, Xiaoli Ma   +5 more
doaj   +1 more source

Lipid-lowering drug prescriptions in a group of Colombian patients

Biomédica: revista del Instituto Nacional de Salud, 2019
Introduction. Lipid-lowering drugs, especially statins, have shown great relevance in preventing and treating cardiovascular diseases. Objective. To determine the prescription patterns of lipid-lowering drugs and the variables associated with their use ...
Andres Gaviria-Mendoza, Manuel E. Machado-Duque, Jorge E. Machado-Alba   +2 more
doaj   +1 more source

Hypoglycaemic and hypolipidemic effects of pumpkin (Cucurbita pepo L.) on alloxan-induced diabetic rats [PDF]

, 2011
This study was aimed to evaluate the hypoglycaemic and hypolipidemic effects of different doses of pumpkin (Cucurbita pepo L.) powder in male diabetic rats.
Adelnia, Azadeh., Asgary, Sedigheh., Kazemi, Somayeh., Moshtaghian, Seyed Jamal., Rafieian-Kopaei, Mahmoud., Setorki, Mahbubeh., Shamsi, Fatemeh.   +6 more
core   +1 more source

Hypolipidemic and Antioxidant Activities of Leptadenia hastata (Perse) Decne. Leaf and Syzygium aromaticum L. Bud Combination: In Vivo, In Vitro, and In Silico Evaluation

Food Chemistry International, EarlyView.
Combination of the Leptadenia hastata leaf and the Syzygium aromaticum bud demonstrated hypolipidemic and antioxidant activities in a hyperlipidemic rat model. Combination of the two plants inhibited HMG‐CoA reductase activity, and the docking analysis revealed interacted well and formed binding complexes within the binding pocket of the enzyme ...
Farida Salisu Dabo, Fatima Aminu, Fatima Auwal Likoro, Shukurat Eniola Kazeem, Aliyu Mansir, Mukhtar Adeiza Suleiman, Hafsat Abdullahi Mohammed, Aminu Mohammed   +7 more
wiley   +1 more source

Hypolipidemic Effects of β-Glucans, Mannans, and Fucoidans: Mechanism of Action and Their Prospects for Clinical Application

Molecules, 2020
The search for lipid-lowering drugs is important for clinical medicine. This review summarizes our research findings regarding the hypolipidemic activity of polysaccharides.
Tatiana A. Korolenko, Nataliya P. Bgatova, Marina V. Ovsyukova, Alexandra Shintyapina, Vaclav Vetvicka   +4 more
doaj   +1 more source