Results 51 to 60 of about 3,173,890 (267)

A staged screening of registered drugs highlights remyelinating drug candidates for clinical trials [PDF]

open access: yes, 2017
There is no treatment for the myelin loss in multiple sclerosis, ultimately resulting in the axonal degeneration that leads to the progressive phase of the disease.
Agresti, C.   +11 more
core   +2 more sources

Cost analysis of oral hypolipidemic agents available in India

open access: yes, 2014
Background: Cardiovascular diseases are the most prevalent cause of death and disability in developed and developing countries. There is a wide variation in the prices of hypolipidemic drugs marketed in India.
Vihang S. Chawan   +2 more
semanticscholar   +1 more source

Use of lipid-lowering medicinal herbs during pregnancy: A systematic review on safety and dosage [PDF]

open access: yes, 2017
BACKGROUND: Hyperlipidemia is one of the important diseases in pregnancy that causes fetal abnormalities during pregnancy and after the birth. Unfortunately, the usual anti-fat drugs are associated with high morbidity in fetus and due to people's ...
Gharipour, M.   +5 more
core   +8 more sources

Hypolipidemic Effects of β-Glucans, Mannans, and Fucoidans: Mechanism of Action and Their Prospects for Clinical Application

open access: yesMolecules, 2020
The search for lipid-lowering drugs is important for clinical medicine. This review summarizes our research findings regarding the hypolipidemic activity of polysaccharides.
Tatiana A. Korolenko   +4 more
doaj   +1 more source

A randomised controlled trial on hypolipidemic effects of Nigella Sativa seeds powder in menopausal women [PDF]

open access: yes, 2014
Background: The risk of cardiovascular diseases (CVD) is increased tremendously among menopausal women, and there is an increasing demand for alternative therapies for managing factors like dyslipidemia that contribute to CVD development.
Abd Ghafar, Siti Aisyah   +8 more
core   +2 more sources

A hepatoprotective experiment on taro vegetable (Colocasia esculenta (L.) Schott) flower employing animal models by mitigating oxidative stress

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The antioxidant efficacy of Colocasia esculenta flower’s methanolic extract was assessed using 2,2′‐azino‐bis‐(3‐ethylbenzothiazoline‐6‐sulfonic) (ABTS) and 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) scavenging assay. The hepatoprotective effect was investigated by assessing liver injury indicators (amino transferase [ALT], aspartate amino transferase [AST],
Mahathir Mohammad   +9 more
wiley   +1 more source

Organ toxicities associated with diet‐induced obesity in rats: Investigation of changes in activities selected enzymes

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
Abstract Obesity stands out as one of the most significant health problems in the modern world. The prevalence of high‐calorie diets (HCDs) globally exacerbates this condition. Throughout history, plants and plant‐derived food products have been utilized for medicinal purposes, demonstrating their efficacy in the treatment and prevention of various ...
Bedia Bati
wiley   +1 more source

Chemical Genetics of Acetyl-CoA Carboxylases [PDF]

open access: yes, 2013
Chemical genetic studies on acetyl-CoA carboxylases (ACCs), rate-limiting enzymes in long chain fatty acid biosynthesis, have greatly advanced the understanding of their biochemistry and molecular biology and promoted the use of ACCs as targets for ...
Deliang Cao   +9 more
core   +2 more sources

Actinidia spp. (Kiwifruit): A Comprehensive Review of Its Nutraceutical Potential in Disease Mitigation and Health Enhancement

open access: yesFood Frontiers, EarlyView.
Nutraceutical Potential in Disease Mitigation and Health Enhancement of Actinidia spp. (Kiwifruit) ABSTRACT This review offers an in‐depth exploration of the Actinidia species (kiwifruit) nutritional composition, the pivotal role of its primary bioactive compounds, and their potential applications across the aforementioned health concerns. Furthermore,
Allah Rakha   +7 more
wiley   +1 more source

Nafenopin-induced rat liver peroxisome proliferation reduces DNA methylation by N-nitrosodimethylamine in vivo [PDF]

open access: yes, 2017
The hypolipidaemic drug nafenopin (NAF) has been shown to enhance the hepatocarcinogenic effect of N-nitrosodimethylamine (NDMA) and N-nitrosodiethylamine in rats.
Fringes, Birgitta   +4 more
core  

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