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Hypoplastic left heart syndrome [PDF]

open access: yesOrphanet Journal of Rare Diseases, 2007
Hypoplastic left heart syndrome(HLHS) refers to the abnormal development of the left-sided cardiac structures, resulting in obstruction to blood flow from the left ventricular outflow tract. In addition, the syndrome includes underdevelopment of the left
Thiagarajan Ravi, Connor Jean
doaj   +5 more sources

Hypoplastic left heart syndrome: a review [PDF]

open access: yesActa Medica Lituanica, 2016
Background. Hypoplastic left heart syndrome (HLHS) is an etiologically multifactorial congenital heart disease affecting one in 5,000 newborns. Thirty years ago there were no treatment options for this pathology and the  natural course of the  disease ...
Roberts Gobergs   +2 more
doaj   +3 more sources

Hypoplastic left heart syndrome – Unresolved Issues [PDF]

open access: yesFrontiers in Pediatrics, 2014
Hypoplastic left heart syndrome (HLHS) is one of the most challenging congenital heart defects. At present it is expected that - at best - 70% of newborns with HLHA will reach adulthood. This review addresses the problems of right ventricular failure and
Raoul Roman Arnold   +2 more
doaj   +3 more sources

Hypoplastic left heart syndrome with mitral regurgitation: a new marker of poor fetal outcome [PDF]

open access: yesJournal of Ultrasonography
Hypoplastic left heart syndrome is a severe congenital heart defect that may be accompanied by tricuspid and mitral valve regurgitation. The aim of this paper is to identify a new ultrasound marker for evaluating the outcomes of fetuses with hypoplastic ...
Witkowski Sławomir   +2 more
doaj   +2 more sources

Autologous umbilical cord blood mononuclear cell therapy for hypoplastic left heart syndrome: a nonrandomized control trial of the efficacy and safety of intramyocardial injections [PDF]

open access: yesStem Cell Research & Therapy
Background Preliminary phase I clinical trial results revealed that autologous umbilical cord blood-derived mononuclear cells (UCB-MNCs) preserved right ventricular cardiac function.
Carlos Gallego-Navarro   +10 more
doaj   +2 more sources

A rare case of hypoplastic left heart syndrome in pregnancy and its outcome [PDF]

open access: yesNew Indian Journal of OBGYN, 2022
Hypoplastic left heart syndrome is abnormal development of left sided cardiac structure, leading to obstruction to blood flow from the left ventricular outflow tract.
Akshatha DS   +4 more
doaj   +1 more source

Hypoplastic left heart syndrome [PDF]

open access: yesBMJ, 1997
Hypoplastic left heart syndrome is not an uncommon condition and accounts for about 10% of critical congenital heart disease in infants. Each year in Britain about 200 children will be born with this condition, which, unlike some other congenital cardiac lesions, usually occurs without serious associated non-cardiac malformations.
S W, O'Kelly, E L, Bove
  +7 more sources

Hypoplastic Left Heart Syndrome [PDF]

open access: yesRadioGraphics, 2001
Hypoplastic left heart syndrome (HLHS) is a complex combination of cardiac malformations that probably results from multiple developmental errors in the early stages of cardiogenesis and that, if left untreated, invariably proves fatal. A variety of chest radiographic findings are seen in patients with HLHS, including an enlarged cardiac silhouette ...
D M, Bardo   +4 more
openaire   +4 more sources

Transcriptome studies of congenital heart diseases: identifying current gaps and therapeutic frontiers

open access: yesFrontiers in Genetics, 2023
Congenital heart disease (CHD) are genetically complex and comprise a wide range of structural defects that often predispose to - early heart failure, a common cause of neonatal morbidity and mortality.
Nkechi Martina Odogwu   +6 more
doaj   +1 more source

Hypoplastic Left Heart Syndrome: A Case Report

open access: yesJournal of Nepal Medical Association, 2023
Hypoplastic left heart syndrome is a rare critical congenital heart defect constituting a prevalence of 1/3,500 to 1/12,500 live births in which there is obstructions to the blood flow within the left heart.
Sunil Raja Manandhar   +4 more
doaj   +1 more source

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