Hypoplastic left heart syndrome [PDF]
Orphanet Journal of Rare Diseases, 2007 Hypoplastic left heart syndrome(HLHS) refers to the abnormal development of the left-sided cardiac structures, resulting in obstruction to blood flow from the left ventricular outflow tract. In addition, the syndrome includes underdevelopment of the left
Thiagarajan Ravi, Connor Jean
doaj +9 more sources
Hypoplastic left heart syndrome: a review [PDF]
Acta Medica Lituanica, 2016 Background. Hypoplastic left heart syndrome (HLHS) is an etiologically multifactorial congenital heart disease affecting one in 5,000 newborns. Thirty years ago there were no treatment options for this pathology and the natural course of the disease ...
Roberts Gobergs +2 more
doaj +3 more sources
Hypoplastic left heart syndrome – Unresolved Issues [PDF]
Frontiers in Pediatrics, 2014 Hypoplastic left heart syndrome (HLHS) is one of the most challenging congenital heart defects. At present it is expected that - at best - 70% of newborns with HLHA will reach adulthood. This review addresses the problems of right ventricular failure and
Raoul Roman Arnold +2 more
doaj +3 more sources
What Is the Hypoplastic Left Heart Syndrome? [PDF]
Journal of Cardiovascular Development and Disease, 2023 As yet, there is no agreed definition for the so-called “hypoplastic left heart syndrome”. Even its origin remains contentious. Noonan and Nadas, who as far as we can establish first grouped together patients as belonging to a “syndrome” in 1958 ...
Robert H. Anderson +2 more
doaj +2 more sources
The neurodevelopmental implications of hypoplastic left heart syndrome in the fetus [PDF]
, 2016 As survival after cardiac surgery continues to improve, an increasing number of patients with hypoplastic left heart syndrome are reaching school age and beyond, with growing recognition of the wide range of neurodevelopmental challenges many survivors ...
Lloyd, David +3 more
core +3 more sources
Hypoplastic left heart syndrome with mitral regurgitation: a new marker of poor fetal outcome [PDF]
Journal of UltrasonographyHypoplastic left heart syndrome is a severe congenital heart defect that may be accompanied by tricuspid and mitral valve regurgitation. The aim of this paper is to identify a new ultrasound marker for evaluating the outcomes of fetuses with hypoplastic ...
Witkowski Sławomir +2 more
doaj +2 more sources
Autologous umbilical cord blood mononuclear cell therapy for hypoplastic left heart syndrome: a nonrandomized control trial of the efficacy and safety of intramyocardial injections [PDF]
Stem Cell Research & TherapyBackground Preliminary phase I clinical trial results revealed that autologous umbilical cord blood-derived mononuclear cells (UCB-MNCs) preserved right ventricular cardiac function.
Carlos Gallego-Navarro +10 more
doaj +2 more sources
Resource and cost considerations in treating hypoplastic left heart syndrome
Pediatric Health, Medicine and Therapeutics, 2016 Miguel Urencio,1 Chris Greenleaf,1 Jorge D Salazar,2 Ali Dodge-Khatami2 1Division of Cardiothoracic Surgery, 2Children’s Heart Center, University of Mississippi Medical Center, Jackson, MS, USA Abstract: Hypoplastic left heart syndrome (HLHS) was a
Urencio M +3 more
doaj +3 more sources
First report of hypoplastic left heart syndrome in 3p- syndrome and review of candidate genes [PDF]
Revista Paulista de PediatriaObjective: 3p deletion syndrome is a rare monosomal disease that encompasses deletions throughout the short arm of chromosome 3. It is often in the distal region (3p25-pter), but variations in breakpoints and a complex clinical manifestation exist, with ...
Ana Kalise Böttcher +7 more
doaj +2 more sources
A rare case of hypoplastic left heart syndrome in pregnancy and its outcome [PDF]
New Indian Journal of OBGYN, 2022 Hypoplastic left heart syndrome is abnormal development of left sided cardiac structure, leading to obstruction to blood flow from the left ventricular outflow tract.
Akshatha DS +4 more
doaj +1 more source