Results 141 to 150 of about 72,312 (262)

Effects of bariatric surgery upon the sympathetic nervous system and hypothalamic-pituitary-adrenal axis in obese humans. [PDF]

Sci Rep
Ziegler AK, Christensen M, Jørgensen HL, Fenger M, Myrup SF, Dirksen C, Madsbad S.   +6 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Evaluation of the Hypothalamic-Pituitary-Adrenal Axis in Patients with Primary Sjögren's Disease. [PDF]

Medicina (Kaunas)
Glavina A, Zurak P, Martinović D, Gotovac M, Šupe-Domić D, Lugović-Mihić L.   +5 more
europepmc   +1 more source

Gut microbiota as a novel therapeutic target for eating disorders and obesity

British Journal of Pharmacology, EarlyView.
The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė, Victor Mathis, Emmanuel Darcq, Aurelijus Burokas, Elena Martín‐García, Rafael Maldonado   +5 more
wiley   +1 more source

Herbal Neuroprotection Meets Stress-Induced Neuropathology: Bojungikgi-Tang Modulates the Hypothalamic-Pituitary-Adrenal Axis and GABAergic Pathways in Post-Traumatic Stress Disorder. [PDF]

Biomedicines
Cai M, Park HR, Yang EJ.
europepmc   +1 more source

Hypogonadotropic Hypogonadism Before and After Transsphenoidal Surgery for Non‐Functioning Pituitary Adenoma

Clinical Endocrinology, EarlyView.
ABSTRACT Objective The effect of transsphenoidal surgery (TSS) on the hypothalamic‐pituitary‐gonadal (HPG) axis in patients with non‐functioning pituitary adenomas (NFPA) is underexplored, especially in women. Our aim was to investigate the HPG axis function before and after TSS, its association with quality of life (QoL), and to identify factors that ...
Victor Hantelius, Gudmundur Johannsson, Sofie Jakobsson, Erik Thurin, Tobias Hallen, Thomas Skoglund, Oskar Ragnarsson   +6 more
wiley   +1 more source

Challenges in Diagnosing Central Adrenal Insufficiency in Children: Cortisol‐Stimulating Tests are Safe and Often Required

Clinical Endocrinology, EarlyView.
ABSTRACT Introduction The accuracy and safety of cortisol‐stimulating tests (CSTs) for assessing hypothalamic–pituitary–adrenal (HPA) axis integrity, including the diagnosis of central adrenal insufficiency (CAI), in children remain uncertain. Although these tests can simultaneously evaluate cortisol and growth hormone secretion, the present study ...
Mariana Peduti Halah, Ana Carolina Maia Teodózio, Davi Casale Aragon, Paula Conde Lamparelli Elias, Margaret de Castro, Ayrton Custodio Moreira, Sonir Rauber Antonini   +6 more
wiley   +1 more source

Hypothalamic-Pituitary-Adrenal Axis Dysfunction in People With Cancer: A Systematic Review. [PDF]

Cancer Med
Kanter NG, Cohen-Woods S, Balfour DA, Burt MG, Waterman AL, Koczwara B.   +5 more
europepmc   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Assessment of hypothalamic-pituitary-adrenal axis impairment and effects of hydrocortisone treatment in adults with Prader-Willi syndrome. [PDF]

Front Endocrinol (Lausanne)
Góralska M, Pokrzywa A, Stańczyk A, Libura M, Bednarczuk T.   +4 more
europepmc   +1 more source