Results 141 to 150 of about 96,734 (308)

Interaction between hypothalamic-pituitary-adrenal axis genetic variation and maternal behavior in the prediction of amygdala connectivity in children

, 2019
Interaction between hypothalamic-pituitary-adrenal axis genetic variation and maternal behavior in the prediction of amygdala connectivity in ...
SL Whittle (14469471), MBH Yap (9674873), NB Allen (14462007), E Pozzi (24301), JG Simmons (14462010), O Schwartz (13478263), M Seal (13457796), CA Bousman (14453433), Nandi Vijayakumar (13087998)   +8 more
core  

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source

Basal morning serum cortisol for the assessment of hypothalamic, pituitary adrenal axis function [PDF]

, 2008
Background: The study of hypothalamic, pituitary adrenal axis function requires complex tests. However, the measurement of basal morning serum cortisol levels may be a simple measure to evaluate this axis.
Wohllk González, Nelson, Ladrón de Guevara, Amanda, Díaz V., Erika, García M., Marisol   +3 more
core  

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Sex-specific prediction of hypothalamic-pituitary-adrenal axis activity by pituitary volume during adolescence: A longitudinal study from 12 to 17 years of age

, 2013
Sex-specific prediction of hypothalamic-pituitary-adrenal axis activity by pituitary volume during adolescence: A longitudinal study from 12 to 17 years of ...
S Whittle (13363980), AM Chanen (14447541), NB Allen (14462007), M Kaess (13448217), C Pantelis (10229780), JG Simmons (14462010), M Jovev (13413564), M Yücel (13307415)   +7 more
core  

Safety of 8‐Week Administration With Ashwagandha (Withania somnifera) Root Extract in Adults With Stress and Anxiety: Findings From a Prospective, Randomized, Multi‐Center, Double‐Blinded, Placebo‐Controlled Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha (Withania somnifera) has been recognized for enhancing physical strength, mental well‐being, and overall vitality. Despite its long‐standing use across generations, some clinical reports have noted occasional adverse events. This study compared the safety and tolerability of Ashwagandha Root Extract (ARE) in healthy adults.
Ketan Pakhale, Jaising Salve, John Ademola, Jose Parraca, Deepak Langade   +4 more
wiley   +1 more source

Impact of biological/targeted versus conventional synthetic disease‐modifying antirheumatic drugs on patient‐reported outcomes in rheumatoid arthritis

Rheumatology &Autoimmunity, EarlyView.
Patient‐reported outcomes (PROs) were compared among rheumatoid arthritis patients who maintained low disease activity or remission for at least 6 months based on the disease‐modifying antirheumatic drug (DMARD)administered. Even with comparable disease activity, methotrexate (MTX) group, biological/targeted synthetic DMARDs (b/tsDMARDs), particularly ...
Masafumi Sugiyama, Saki Okuda‐Tsuchimoto, Takashi tsuchimoto, Koji Kinoshita, Itaru Matsumura   +4 more
wiley   +1 more source

Ghrelin's role in the hypothalamic-pituitary-adrenal axis in response to stress

, 2015
Ghrelin is a stomach hormone normally associated with feeding behavior and energy homeostasis. Recent studies highlight that ghrelin targets the brain to regulate a diverse number of functions, including learning, memory, motivation, stress responses ...
Z.B Andrews (20028033), Tim Emmerzaal (20042877), Tamas Kozicz (1667500), Sarah Spencer (18025435)   +3 more
core  

Obstructive sleep apnea and major depressive disorder: Shared transcriptional signatures and candidate pathways identified via bioinformatics analysis

Sleep Research, EarlyView.
Abstract Background Obstructive sleep apnea (OSA) frequently co‐occurs with major depressive disorder (MDD). However, the underlying biological mechanisms remain unclear. This study aimed to identify OSA‐related transcriptional signatures associated with depressive status using integrated bioinformatics and machine learning.
Yun‐Shu Sun, Fei Wang, Qian‐Ting Zhong, Shi‐Bin Wang, Fu‐Jun Jia, Cai‐Lan Hou   +5 more
wiley   +1 more source

Salivary biomarkers in sleep‐related disorders

Sleep Research, EarlyView.
Abstract The exploration of salivary biomarkers has emerged as a promising avenue in the diagnosis and management of sleep‐related disorders, such as obstructive sleep apnea (OSA), insomnia, and sleep deprivation. Saliva is a noninvasive biofluid that contains a wealth of biological markers, reflecting both local and systemic physiological changes ...
Chuan Xiang Li, Yi Wang, Ying Ni Lin, Jun Qi Lin, Ya Ru Yan, Xian wen Sun, Liu Zhang, Shi Qi Li, Ning Li, Qing Yun Li   +9 more
wiley   +1 more source