Results 261 to 270 of about 922,924 (304)
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Hypothalamic-pituitary-adrenal Axis and Bipolar Disorder
Psychiatric Clinics of North America, 2005There is robust evidence demonstrating abnormalities of the HPA axis in bipolar disorder. Hypercortisolism may be central to the pathogenesis of depressive symptoms and cognitive deficits, which may in turn result from neurocytotoxic effects of raised cortisol levels.
C, Daban +3 more
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Hypothalamic-Pituitary-Adrenal Axis in Psychiatric Disorders
Annual Review of Medicine, 1991Hypothalamic-pituitary-adrenocortical (HPA) physiology is complex, and dysregulation of this neuroendocrine axis cannot be characterized adequately by isolated or unintegrated measures. Repeated assessments over time, involving multiple measures of axis activity (basal and dynamic tests), have furthered our understanding of the character of the HPA ...
P E, Stokes, C R, Sikes
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Effects of vindesine on hypothalamic-pituitary-adrenal axis
Toxicology Letters, 1995Vindesine, a cell-cycle-specific agent currently employed in the treatment of some neoplasias, was able to produce a remarkable dose-dependent adrenocortical activation, but it was unable to increase plasma corticosterone in hypophysectomized rats in vivo.
BRUNETTI, Luigi +3 more
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The Hypothalamic-Pituitary-Adrenal Axis: A Brief History
Hormone Research in Paediatrics, 2018The hypothalamic-pituitary-adrenal (HPA) axis is central to homeostasis, stress responses, energy metabolism, and neuropsychiatric function. The history of this complex system involves discovery of the relevant glands (adrenal, pituitary, hypothalamus), hormones (cortisol, corticotropin, corticotropin-releasing hormone), and the receptors for these ...
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Leptin and the Regulation of the Hypothalamic–Pituitary–Adrenal Axis
2007Leptin, the product of the obesity gene (ob) predominantly secreted from adipocytes, plays a major role in the negative control of feeding and acts via a specific receptor (Ob-R), six isoforms of which are known at present. Evidence has been accumulated that leptin, like other peptides involved in the central regulation of food intake, controls the ...
Malendowicz LK +4 more
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Hypothalamic‐Pituitary‐Adrenal Axis and Suicide
Annals of the New York Academy of Sciences, 1986M, Arató +3 more
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Suicide and the hypothalamic-pituitary-adrenal axis
The Lancet, 2005Elizabeth A, Young, William, Coryell
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