Results 31 to 40 of about 124,713 (209)
Besides the well-known function of thyroid hormones (THs) for regulating metabolism, it has recently been discovered that THs are also involved in testicular development in mammalian and non-mammalian species.
Diana C. Castañeda Cortés +2 more
doaj +1 more source
The role of photoperiod and melatonin in the control of seasonal reproduction in mammals [PDF]
Melatonin secreted by pineal cells is a hormone whose biosynthesis is coordinated by neurons of the master clock located in the hypothalamic suprachiasmatic nuclei (SCN), characterized by the generation of a 24-hour rhythm.
Izabela Szpręgiel, Danuta Wronska
doaj +1 more source
Onset, timing, and exposure therapy of stress disorders: mechanistic insight from a mathematical model of oscillating neuroendocrine dynamics [PDF]
The hypothalamic-pituitary-adrenal (HPA) axis is a neuroendocrine system that regulates numerous physiological processes. Disruptions in the activity of the HPA axis are correlated with many stress-related diseases such as post-traumatic stress disorder (
Chou, Tom +2 more
core +3 more sources
Activation of mammalian target of rapamycin 1 (mTORC1) by nutrients, insulin and leptin leads to appetite suppression (anorexia). Contrastingly, increased AMP-activated protein kinase (AMPK) activity by ghrelin promotes appetite (orexia).
Kenneth R. Watterson +6 more
doaj +1 more source
Proliferative hypothalamic neurospheres express NPY, AGRP, POMC, CART and Orexin-A and differentiate to functional neurons. [PDF]
Some pathological conditions with feeding pattern alterations, including obesity and Huntington disease (HD) are associated with hypothalamic dysfunction and neuronal cell death. Additionally, the hypothalamus is a neurogenic region with the constitutive
Lígia Sousa-Ferreira +7 more
doaj +1 more source
Increased colonic propionate reduces anticipatory reward responses in the human striatum to high-energy foods [PDF]
Background: Short-chain fatty acids (SCFAs), metabolites produced through the microbial fermentation of nondigestible dietary components, have key roles in energy homeostasis.
Alhabeeb, Habeeb +14 more
core +1 more source
Sexual Dimorphism and Hypothalamic Astrocytes: Focus on Glioprotection
Sexual dimorphism refers to biological differences between males and females in the same species, including morphological, physiological, and behavioral characteristics.
Natalie K. Thomaz +2 more
doaj +1 more source
Male reproduction is governed by the classical hypothalamo-hypophyseal testicular axis: Hypothalamic gonadotropin releasing hormone (GnRH), pituitary luteinizing hormone (LH) and follicle stimulating hormone (FSH) and the gonadal steroid, principally ...
Anand Kumar +2 more
doaj +1 more source
Interaction of glucose sensing and leptin action in the brain
Background: In response to energy abundant or deprived conditions, nutrients and hormones activate hypothalamic pathways to maintain energy and glucose homeostasis. The underlying CNS mechanisms, however, remain elusive in rodents and humans.
Rosa J.W. Li +2 more
doaj +1 more source
Leptin fails to blunt the lipopolysaccharide-induced activation of the hypothalamic-pituitary-adrenal axis in rats [PDF]
Copyright @ 2013 The authors. This work is licensed under a Creative Commons Attribution 3.0 Unported License.Obesity is a risk factor for sepsis morbidity and mortality, whereas the hypothalamic-pituitary-adrenal (HPA) axis plays a protective role in ...
Ahima +40 more
core +1 more source

