Role of the hypothalamic paraventricular nucleus in anxiety disorders
Stress and Brain, 2022 The hypothalamic paraventricular nucleus (PVN) expresses multiple neuropeptides and plays an essential role in several physiological processes. Among the brain areas directly projecting to the PVN are deep brain structures closely related to instinctive ...
Chen Wu, Mario A. Zetter
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Dysfunctions of the paraventricular hypothalamic nucleus induce hypersomnia in mice
eLife, 2021 Hypersomnolence disorder (HD) is characterized by excessive sleep, which is a common sequela following stroke, infection, or tumorigenesis. HD is traditionally thought to be associated with lesions of wake-promoting nuclei.
Chang-Rui Chen +7 more
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Curcumin mitigates the sleep-deprivation impacts on rat hypothalamic paraventricular nucleus [PDF]
IBRO Neuroscience Reports, 2023 Introduction: The paraventricular nucleus of the hypothalamus (PVH) is an important efferent system that relays the circadian rhythm of sleep and stress information to the periphery.
Mahboobeh Erfanizadeh +4 more
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Distinct Hypothalamic Paraventricular Nucleus Inputs to the Cingulate Cortex and Paraventricular Thalamic Nucleus Modulate Anxiety and Arousal [PDF]
Frontiers in Pharmacology, 2022 Insomnia and anxiety are two common clinical diseases that threaten people’s physical and mental health. Insomnia and anxiety may share some similar underlying neural circuit mechanisms in the brain.
Ying Liu +7 more
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Journal of Neuroinflammation, 2020 Background Cardiovascular diseases, including heart failure, are the most common cause of death globally. Recent studies support a high degree of comorbidity between heart failure and cognitive and mood disorders resulting in memory loss, depression, and
Ferdinand Althammer +6 more
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Effects of Nrf1 in Hypothalamic Paraventricular Nucleus on Regulating the Blood Pressure During Hypertension [PDF]
Frontiers in Neuroscience, 2021 The incidence rate and mortality of hypertension increase every year. Hypothalamic paraventricular nucleus (PVN) plays a critical role on the pathophysiology of hypertension.
Xiao-Jing Yu +9 more
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Neurogenic Hypotension and Bradycardia Modulated by Electroacupuncture in Hypothalamic Paraventricular Nucleus [PDF]
Frontiers in Neuroscience, 2022 Electroacupuncture (EA) stimulates somatic median afferents underlying P5-6 acupoints and modulates parasympathoexcitatory reflex responses through central processing in the brainstem.
Stephanie C. Tjen-A-Looi +6 more
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Cardiovascular responses to chemical stimulation of the hypothalamic arcuate nucleus in the rat: role of the hypothalamic paraventricular nucleus. [PDF]
PLoS ONE, 2012 The mechanism of cardiovascular responses to chemical stimulation of the hypothalamic arcuate nucleus (ARCN) was studied in urethane-anesthetized adult male Wistar rats.
Tetsuya Kawabe +2 more
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Frontiers in neuroendocrinology (Print), 2022 Estradiol and hypothalamic paraventricular nucleus (PVN) help coordinate reproduction with body physiology, growth and metabolism. PVN integrates hormonal and neural signals originating in the periphery, generating an output mediated both by its long ...
D. Grassi +3 more
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Bilateral descending hypothalamic projections to the spinal trigeminal nucleus caudalis in rats. [PDF]
PLoS ONE, 2013 Several lines of evidence suggest that the hypothalamus is involved in trigeminal pain processing. However, the organization of descending hypothalamic projections to the spinal trigeminal nucleus caudalis (Sp5C) remains poorly understood ...
Khaled Abdallah +4 more
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