Results 11 to 20 of about 444,141 (265)

Local Corticotropin-Releasing Factor Signaling in the Hypothalamic Paraventricular Nucleus [PDF]

The Journal of Neuroscience, 2018
Corticotropin-releasing factor (CRF) neurons in the hypothalamic paraventricular nucleus (PVN) initiate hypothalamic–pituitary–adrenal axis activity through the release of CRF into the portal system as part of a coordinated neuroendocrine, autonomic, and
Zhiying Jiang, Shivakumar Rajamanickam, N. Justice   +2 more
semanticscholar   +5 more sources

Dynamism of chemoarchitecture in the hypothalamic paraventricular nucleus

Brain Research Bulletin, 1988
The hypothalamic paraventricular nucleus (PVN) has been implicated in a remarkable number of functions including control of pituitary-adrenocortical activity in response to stress, body fluid homeostasis, milk ejection reflex, prolactin secretion, thyroid hormone secretion, analgesia, food intake, gastrointestinal functions, cardiovascular functions ...
Kiss, Jozsef Zoltan, Kiss JZ
openaire   +4 more sources

Orexin depolarizes rat hypothalamic paraventricular nucleus neurons [PDF]

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2001
Orexins, also called hypocretins, are newly discovered hypothalamic peptides that are thought to be involved in various physiological functions. In spite of the fact that orexin receptors, especially orexin receptor 2, are abundant in the hypothalamic paraventricular nucleus (PVN), the effects of orexins on PVN neurons remain unknown.
T, Shirasaka, S, Miyahara, T, Kunitake, Q H, Jin, K, Kato, M, Takasaki, H, Kannan   +6 more
openaire   +3 more sources

The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system. [PDF]

PLoS ONE, 2008
Ghrelin and cannabinoids stimulate appetite, this effect possibly being mediated by the activation of hypothalamic AMP-activated protein kinase (AMPK), a key enzyme in appetite and metabolism regulation.
Blerina Kola, Imre Farkas, Mirjam Christ-Crain, Gábor Wittmann, Francesca Lolli, Faisal Amin, Judith Harvey-White, Zsolt Liposits, George Kunos, Ashley B Grossman, Csaba Fekete, Márta Korbonits   +11 more
doaj   +4 more sources

c-Fos expression in the hypothalamic paraventricular nucleus after a single treatment with a typical haloperidol and nine atypical antipsychotics: a pilot study

Endocrine Regulations, 2018
Objective. The aim of the present study was to find out whether acute effect of different doses of selected antipsychotics including aripiprazole (ARI), amisulpride (AMI), asenapine (ASE), haloperidol (HAL), clozapine (CLO), risperidone (RIS), quetiapine
Kiss Alexander
doaj   +2 more sources

Organotypic slice culture of the hypothalamic paraventricular nucleus of rat [PDF]

Journal of Veterinary Science, 2007
Organotypic slice cultures have been developed as an alternative to acute brain slices because the neuronal viability and synaptic connectivity in these cultures can be preserved well for a prolonged period of time. This study evaluated a stationary organotypic slice culture developed for the hypothalamic paraventricular nucleus (PVN) of rat.
Cho, Eun Seong, Lee, So Yeong, Park, Jae-Yong, Hong, Seong-Geun, Ryu, Pan Dong   +4 more
openaire   +3 more sources

Electrophysiological Effects of Ghrelin in the Hypothalamic Paraventricular Nucleus Neurons

Frontiers in Cellular Neuroscience, 2018
The paraventricular nucleus (PVN) is involved in the control of sympathetic tone and the secretion of hormones, both functions known to be influenced by ghrelin, suggesting direct effect of ghrelin in this nucleus.
Raoni C. dos-Santos, Hanna M. Grover, Luís C. Reis, Alastair V. Ferguson, André S. Mecawi, André S. Mecawi   +5 more
doaj   +3 more sources

Feeding inhibition by urocortin in the rat hypothalamic paraventricular nucleus

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2001
Ventricular administration of urocortin (UCN) inhibits feeding, but specific site(s) of UCN action are unknown. In the current studies we examined the effect of UCN in the hypothalamic paraventricular nucleus (PVN) on feeding. We tested UCN administered into the PVN in several paradigms: deprivation-induced, nocturnal, and neuropeptide Y (NPY)-induced
C, Wang, M A, Mullet, M J, Glass, C J, Billington, A S, Levine, C M, Kotz   +5 more
openaire   +3 more sources

The microbiota shapes the development of the mouse hypothalamic paraventricular nucleus. [PDF]

Horm Behav
Microbes massively colonize the mammalian newborn at birth. We previously reported that the microbiota influences key neurodevelopmental events, e.g., when compared to their conventionally colonized (CC) counterparts, sterile newborn mice ("germ-free" or GF) show higher cell death in the hypothalamic paraventricular nucleus (PVN).
Milligan YC, Peters NV, West G, Cortes LR, Chassaing B, de Vries GJ, Castillo-Ruiz A.   +6 more
europepmc   +3 more sources

Glucose in the hypothalamic paraventricular nucleus regulates GLP-1 release. [PDF]

JCI Insight, 2020
Glucokinase (GK) is highly expressed in the hypothalamic paraventricular nucleus (PVN); however, its role is currently unknown. We found that GK in the PVN acts as part of a glucose-sensing mechanism within the PVN that regulates glucose homeostasis by ...
Ma Y, Ratnasabapathy R, De Backer I, Izzi-Engbeaya C, Nguyen-Tu MS, Cuenco J, Jones B, John CD, Lam BY, Rutter GA, Yeo GS, Dhillo WS, Gardiner J.   +12 more
europepmc   +3 more sources