Results 21 to 30 of about 21,484 (235)
Oxytocin signaling in the posterior hypothalamus prevents hyperphagic obesity in mice
eLife, 2022 Decades of studies have revealed molecular and neural circuit bases for body weight homeostasis. Neural hormone oxytocin (Oxt) has received attention in this context because it is produced by neurons in the paraventricular hypothalamic nucleus (PVH), a ...
Kengo Inada +4 more
doaj +1 more source
Fasting induced cytoplasmic Fto expression in some neurons of rat hypothalamus. [PDF]
PLoS ONE, 2013 Fat mass and obesity associated protein (Fto) is a nucleic acid demethylase, with a preference for thymine or uracil, according to the recent structural data. This fact suggests that methylated single-stranded RNA, rather than DNA, may be the primary Fto
Predrag Vujovic +6 more
doaj +1 more source
Opioids in the Hypothalamic Paraventricular Nucleus Stimulate Ethanol Intake [PDF]
Alcoholism: Clinical and Experimental Research, 2010 Background: Specialized hypothalamic systems that increase food intake might also increase ethanol intake. To test this possibility, morphine and receptor‐specific opioid agonists were microinjected in the paraventricular nucleus (PVN) of rats that had learned to drink ethanol.
Jessica R, Barson +6 more
openaire +2 more sources
Journal of Physiology, 2018 Causal relationships between central cardiovascular pathways and sympathetic vasomotor tone have not been evidenced. This study aimed to verify the sympathoexcitatory role of hypothalamic paraventricular nucleus neurons that project to the rostral ...
S. Koba +5 more
semanticscholar +1 more source
PLoS ONE, 2014 Baroreflex dysfunction, oxidative stress and inflammation, important hallmarks of hypertension, are attenuated by exercise training. In this study, we investigated the relationships and time-course changes of cardiovascular parameters, pro-inflammatory ...
Gustavo S Masson +7 more
doaj +1 more source
Chronic stress plasticity in the hypothalamic paraventricular nucleus [PDF]
, 2008 Proper integration and execution of the physiological stress response is essential for maintaining homoeostasis. Stress responses are controlled in large part by the paraventricular nucleus (PVN) of the hypothalamus, which contains three functionally distinct neural populations that modulate multiple stress effectors: (1) hypophysiotrophic PVN neurons ...
James P, Herman +2 more
openaire +2 more sources
Transcriptional regulation of corticotropin-releasing hormone gene in stress response
IBRO Reports, 2018 As a central player of the hypothalamic-pituitary-adrenal (HPA) axis, the corticotropin -releasing hormone (CRH) neurons in the hypothalamic paraventricular nucleus (PVN) determine the state of HPA axis and play a key role in stress response.
Jiang-Ning Zhou, Hui Fang
doaj +1 more source
Scientific Reports, 2016 High blood pressure, or “hypertension,” is associated with high levels of oxidative stress in the paraventricular nucleus of the hypothalamus. While pomegranate extract is a known antioxidant that is thought to have antihypertensive effects, the ...
Wenyan Sun +8 more
semanticscholar +1 more source
Frontiers in Systems Neuroscience, 2015 This study used immunohistochemical methods to investigate the possibility that hypothalamic neurons that contain 11-β-hydroxysteroid dehydrogenase type 2 (HSD2) are involved in the control of feeding by rats via neuroanatomical associations with the α ...
Maegan L. Askew +3 more
doaj +1 more source
Psychoneuroendocrinology, 2015 Oxytocin (Oxt) is released in various hypothalamic and extrahypothalamic brain areas in response to anxiogenic stimuli to regulate aspects of emotionality and stress coping.
Adam S. Smith +8 more
semanticscholar +1 more source