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The hypothalamus [PDF]

open access: yesCurrent Biology, 2014
SummaryThe hypothalamus is one of the oldest and smallest parts of the brain, constituting just 4 gm of the 1400 gm of adult human brain weight. And yet this tiny area contains highly conserved neural circuitry that controls basic life functions: these include energy metabolism, from feeding through digestion, metabolic control, and energy expenditure;
C. Saper, B. Lowell
semanticscholar   +3 more sources

Conserved Genoarchitecture of the Basal Hypothalamus in Zebrafish Embryos

open access: yesFrontiers in Neuroanatomy, 2020
Analyses of genoarchitecture recently stimulated substantial revisions of anatomical models for the developing hypothalamus in mammalian and other vertebrate systems.
Theresa Schredelseker
exaly   +3 more sources

Regional response to light illuminance across the human hypothalamus [PDF]

open access: yeseLife
Light exerts multiple non-image-forming biological effects on physiology including the stimulation of alertness and cognition. However, the subcortical circuitry underlying the stimulating impact of light is not established in humans.
Islay Campbell   +15 more
doaj   +2 more sources

Molecular codes defining rostrocaudal domains in the embryonic mouse hypothalamus

open access: yesFrontiers in Neuroanatomy, 2015
The prosomeric model proposes that the hypothalamus is a rostral forebrain entity, placed ventral to the telencephalon and rostral to the diencephalon.
Luis Puelles
exaly   +2 more sources

Resting State Functional Connectivity of the Lateral and Medial Hypothalamus in Cocaine Dependence: An Exploratory Study

open access: yesFrontiers in Psychiatry, 2018
The role of dopamine in cocaine misuse has been extensively documented for the mesocorticolimbic circuit. Preclinical work from earlier lesion studies to recent multidisciplinary investigations has suggested that the hypothalamus is critically involved ...
Sheng Zhang, Wuyi Wang, Simon Zhornitsky
exaly   +3 more sources

Molecular design of hypothalamus development

open access: yesNature, 2020
Evgenii O Tretiakov   +2 more
exaly   +2 more sources

Novel Neuroimaging Biomarker for Sleep Quality in Insomnia Disorder: A Hypothalamus Resting State Study

open access: yesFrontiers in Neuroscience, 2021
Despite striking progress in the understanding of the neurobiology of insomnia disorder (ID), about 40% of ID patients do not reach sustained remission with the primary treatments. It is necessary to reveal novel neuroimaging biomarkers for sleep quality
Shuang Ding   +6 more
doaj   +1 more source

Music Enhances Activity in the Hypothalamus, Brainstem, and Anterior Cerebellum during Script-Driven Imagery of Affective Scenes [PDF]

open access: yesNeuropsychologia 133, 107073. Epub 2019 Apr 24, 2023
Music is frequently used to establish atmosphere and to enhance/alter emotion in dramas and films. During music listening, visual imagery is a common mechanism underlying emotion induction. The present functional magnetic resonance imaging (fMRI) study examined the neural substrates of the emotional processing of music and imagined scene.
arxiv   +1 more source

Blast Exposure Induces Acute Alterations in Circadian Clock Genes in the Hypothalamus and Pineal Gland in Rats: An Exploratory Study

open access: yesNeurotrauma Reports, 2023
Blast-induced traumatic brain injury (bTBI) frequently results in sleep and circadian rhythm disturbances. We have investigated whether dysregulation of circadian rhythm after bTBI is mediated by dysregulation of clock genes in the hypothalamus and ...
Manoj Govindarajulu   +4 more
doaj   +1 more source

Long-term exercise training down-regulates m6A RNA demethylase FTO expression in the hippocampus and hypothalamus: an effective intervention for epigenetic modification

open access: yesBMC Neuroscience, 2022
Background Exercise boosts the health of some brain parts, such as the hippocampus and hypothalamus. Several studies show that long-term exercise improves spatial learning and memory, enhances hypothalamic leptin sensitivity, and regulates energy balance.
Shu-Jing Liu   +12 more
doaj   +1 more source

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