Results 1 to 10 of about 299,925 (157)
A central role for C1q/TNF-related protein 13 (CTRP13) in modulating food intake and body weight. [PDF]
, 2013 C1q/TNF-related protein 13 (CTRP13), a hormone secreted by adipose tissue (adipokines), helps regulate glucose metabolism in peripheral tissues. We previously reported that CTRP13 expression is increased in obese and hyperphagic leptin-deficient mice ...
Byerly, Mardi S +5 more
core +23 more sources
Amygdala–hypothalamus–brainstem circuits underlying cardiovascular responses associated with the limits of high-intensity endurance exercise [PDF]
Frontiers in PhysiologyIn athletic competitions, athletes continually challenge the limits of human performance. Exercise limitation refers to a state in which fatigue accumulates during prolonged activity, preventing the maintenance of the required power output despite ...
Ko Yamanaka +7 more
doaj +2 more sources
The long-term impact of obesity in pregnancy on offspring hypothalamic feeding pathways [PDF]
Royal Society Open ScienceAn accumulating body of evidence shows that offspring exposure to maternal obesity in the peri-natal period causes an increased risk to develop obesity later in life.
Pit Shan Chong, Laura Dearden
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Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity
iScience, 2023 Summary: The hypothalamus is a region of the brain that plays an important role in regulating body functions and behaviors. There is a growing interest in human pluripotent stem cells (hPSCs) for modeling diseases that affect the hypothalamus.
Lily Sarrafha +14 more
doaj +1 more source
Complex negative emotions induced by electrical stimulation of the human hypothalamus
Brain Stimulation, 2022 Background: Stimulation of the ventromedial hypothalamic region in animals has been reported to cause attack behavior labeled as sham-rage without offering information about the internal affective state of the animal being stimulated.
Josef Parvizi +13 more
doaj +1 more source
Frontiers in Neuroscience, 2021 Despite striking progress in the understanding of the neurobiology of insomnia disorder (ID), about 40% of ID patients do not reach sustained remission with the primary treatments. It is necessary to reveal novel neuroimaging biomarkers for sleep quality
Shuang Ding +6 more
doaj +1 more source
Current Biology, 2014 SummaryThe hypothalamus is one of the oldest and smallest parts of the brain, constituting just 4 gm of the 1400 gm of adult human brain weight. And yet this tiny area contains highly conserved neural circuitry that controls basic life functions: these include energy metabolism, from feeding through digestion, metabolic control, and energy expenditure;
Saper, Clifford B., Lowell, Bradford B.
openaire +2 more sources
Conserved Genoarchitecture of the Basal Hypothalamus in Zebrafish Embryos
Frontiers in Neuroanatomy, 2020 Analyses of genoarchitecture recently stimulated substantial revisions of anatomical models for the developing hypothalamus in mammalian and other vertebrate systems.
Theresa Schredelseker +3 more
doaj +1 more source
Neurotrauma Reports, 2023 Blast-induced traumatic brain injury (bTBI) frequently results in sleep and circadian rhythm disturbances. We have investigated whether dysregulation of circadian rhythm after bTBI is mediated by dysregulation of clock genes in the hypothalamus and ...
Manoj Govindarajulu +4 more
doaj +1 more source
Oleic acid and octanoic acid sensing capacity in rainbow trout Oncorhynchus mykiss is direct in hypothalamus and Brockmann bodies. [PDF]
PLoS ONE, 2013 In a previous study, we provided evidence for the presence in hypothalamus and Brockmann bodies (BB) of rainbow trout Oncorhynchus mykiss of sensing systems responding to changes in levels of oleic acid (long-chain fatty acid, LCFA) or octanoic acid ...
Marta Librán-Pérez +3 more
doaj +1 more source