Results 1 to 10 of about 245,222 (354)

TDP-43 overexpression in the hypothalamus drives neuropathology, dysregulates metabolism and impairs behavior in mice [PDF]

open access: yesActa Neuropathologica Communications
TAR DNA-binding protein 43 (TDP-43) pathology is linked to the neurodegenerative disorders amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and Huntington disease (HD).
Sofia Bergh   +7 more
doaj   +2 more sources

The hypothalamus [PDF]

open access: yesCurrent Biology, 2014
SummaryThe hypothalamus is one of the oldest and smallest parts of the brain, constituting just 4 gm of the 1400 gm of adult human brain weight. And yet this tiny area contains highly conserved neural circuitry that controls basic life functions: these include energy metabolism, from feeding through digestion, metabolic control, and energy expenditure;
Saper, Clifford B., Lowell, Bradford B.
openaire   +3 more sources

Conserved Genoarchitecture of the Basal Hypothalamus in Zebrafish Embryos

open access: yesFrontiers in Neuroanatomy, 2020
Analyses of genoarchitecture recently stimulated substantial revisions of anatomical models for the developing hypothalamus in mammalian and other vertebrate systems.
Theresa Schredelseker
exaly   +3 more sources

Resting State Functional Connectivity of the Lateral and Medial Hypothalamus in Cocaine Dependence: An Exploratory Study

open access: yesFrontiers in Psychiatry, 2018
The role of dopamine in cocaine misuse has been extensively documented for the mesocorticolimbic circuit. Preclinical work from earlier lesion studies to recent multidisciplinary investigations has suggested that the hypothalamus is critically involved ...
Sheng Zhang, Wuyi Wang, Simon Zhornitsky
exaly   +3 more sources

Novel Neuroimaging Biomarker for Sleep Quality in Insomnia Disorder: A Hypothalamus Resting State Study

open access: yesFrontiers in Neuroscience, 2021
Despite striking progress in the understanding of the neurobiology of insomnia disorder (ID), about 40% of ID patients do not reach sustained remission with the primary treatments. It is necessary to reveal novel neuroimaging biomarkers for sleep quality
Shuang Ding   +6 more
doaj   +1 more source

Blast Exposure Induces Acute Alterations in Circadian Clock Genes in the Hypothalamus and Pineal Gland in Rats: An Exploratory Study

open access: yesNeurotrauma Reports, 2023
Blast-induced traumatic brain injury (bTBI) frequently results in sleep and circadian rhythm disturbances. We have investigated whether dysregulation of circadian rhythm after bTBI is mediated by dysregulation of clock genes in the hypothalamus and ...
Manoj Govindarajulu   +4 more
doaj   +1 more source

Long-term exercise training down-regulates m6A RNA demethylase FTO expression in the hippocampus and hypothalamus: an effective intervention for epigenetic modification

open access: yesBMC Neuroscience, 2022
Background Exercise boosts the health of some brain parts, such as the hippocampus and hypothalamus. Several studies show that long-term exercise improves spatial learning and memory, enhances hypothalamic leptin sensitivity, and regulates energy balance.
Shu-Jing Liu   +12 more
doaj   +1 more source

Age changes in the tigroid substance of neutrons of the lateral preoptic nucleus of hypothalamus under different light modes

open access: yesJournal of Education, Health and Sport, 2021
The article presents analysis of the results of the original histochemical studies of tigroid substance of neurons of the lateral preoptic nucleus of  hypothalamus in mature and old rats under the influence of different light modes. In all observations,
R. Bulyk   +4 more
doaj   +1 more source

Blooming in the Hypothalamus [PDF]

open access: yesJournal of Neurosciences in Rural Practice, 2019
ABSTRACTCavernomas are vascular malformations which are collections of endothelium-lined sinusoids without intervening cerebral parenchyma. Hypothalamic location of cavernoma is extremely rare. We present a case of a 34-year-old male who presented with complaints of recent memory loss and vomiting.
Muralidhar Pai   +3 more
openaire   +2 more sources

Oleic acid and octanoic acid sensing capacity in rainbow trout Oncorhynchus mykiss is direct in hypothalamus and Brockmann bodies. [PDF]

open access: yesPLoS ONE, 2013
In a previous study, we provided evidence for the presence in hypothalamus and Brockmann bodies (BB) of rainbow trout Oncorhynchus mykiss of sensing systems responding to changes in levels of oleic acid (long-chain fatty acid, LCFA) or octanoic acid ...
Marta Librán-Pérez   +3 more
doaj   +1 more source

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