Results 1 to 10 of about 396,606 (377)
VGF changes during the estrous cycle: a novel endocrine role for TLQP peptides? [PDF]
, 2014 Although the VGF derived peptide TLQP-21 stimulates gonadotropin-releasing hormone (GnRH) and gonadotropin secretion, available data on VGF peptides and reproduction are limited.
Brancia C +4 more
core +24 more sources
TDP-43 overexpression in the hypothalamus drives neuropathology, dysregulates metabolism and impairs behavior in mice [PDF]
Acta Neuropathologica CommunicationsTAR DNA-binding protein 43 (TDP-43) pathology is linked to the neurodegenerative disorders amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and Huntington disease (HD).
Sofia Bergh +7 more
doaj +2 more sources
HypoMap—a unified single-cell gene expression atlas of the murine hypothalamus
Nature Metabolism, 2022 The hypothalamus plays a key role in coordinating fundamental body functions. Despite recent progress in single-cell technologies, a unified catalog and molecular characterization of the heterogeneous cell types and, specifically, neuronal subtypes in ...
Lukas Steuernagel +18 more
semanticscholar +1 more source
Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity
iScience, 2023 Summary: The hypothalamus is a region of the brain that plays an important role in regulating body functions and behaviors. There is a growing interest in human pluripotent stem cells (hPSCs) for modeling diseases that affect the hypothalamus.
Lily Sarrafha +14 more
doaj +1 more source
Single-cell analysis of the aging female mouse hypothalamus
Nature Aging, 2022 Alterations in metabolism, sleep patterns, body composition and hormone status are all key features of aging. While the hypothalamus is a well-conserved brain region that controls these homeostatic and survival-related behaviors, little is known about ...
Kaitlyn H. Hajdarovic +6 more
semanticscholar +1 more source
Complex negative emotions induced by electrical stimulation of the human hypothalamus
Brain Stimulation, 2022 Background: Stimulation of the ventromedial hypothalamic region in animals has been reported to cause attack behavior labeled as sham-rage without offering information about the internal affective state of the animal being stimulated.
Josef Parvizi +13 more
doaj +1 more source
Frontiers in Neuroscience, 2021 Despite striking progress in the understanding of the neurobiology of insomnia disorder (ID), about 40% of ID patients do not reach sustained remission with the primary treatments. It is necessary to reveal novel neuroimaging biomarkers for sleep quality
Shuang Ding +6 more
doaj +1 more source
Conserved Genoarchitecture of the Basal Hypothalamus in Zebrafish Embryos
Frontiers in Neuroanatomy, 2020 Analyses of genoarchitecture recently stimulated substantial revisions of anatomical models for the developing hypothalamus in mammalian and other vertebrate systems.
Theresa Schredelseker +3 more
doaj +1 more source
Oleic acid and octanoic acid sensing capacity in rainbow trout Oncorhynchus mykiss is direct in hypothalamus and Brockmann bodies. [PDF]
PLoS ONE, 2013 In a previous study, we provided evidence for the presence in hypothalamus and Brockmann bodies (BB) of rainbow trout Oncorhynchus mykiss of sensing systems responding to changes in levels of oleic acid (long-chain fatty acid, LCFA) or octanoic acid ...
Marta Librán-Pérez +3 more
doaj +1 more source
Neurotrauma Reports, 2023 Blast-induced traumatic brain injury (bTBI) frequently results in sleep and circadian rhythm disturbances. We have investigated whether dysregulation of circadian rhythm after bTBI is mediated by dysregulation of clock genes in the hypothalamus and ...
Manoj Govindarajulu +4 more
doaj +1 more source