Results 11 to 20 of about 243,404 (354)

Long-term exercise training down-regulates m6A RNA demethylase FTO expression in the hippocampus and hypothalamus: an effective intervention for epigenetic modification

open access: yesBMC Neuroscience, 2022
Background Exercise boosts the health of some brain parts, such as the hippocampus and hypothalamus. Several studies show that long-term exercise improves spatial learning and memory, enhances hypothalamic leptin sensitivity, and regulates energy balance.
Shu-Jing Liu   +12 more
doaj   +1 more source

Oleic acid and octanoic acid sensing capacity in rainbow trout Oncorhynchus mykiss is direct in hypothalamus and Brockmann bodies. [PDF]

open access: yesPLoS ONE, 2013
In a previous study, we provided evidence for the presence in hypothalamus and Brockmann bodies (BB) of rainbow trout Oncorhynchus mykiss of sensing systems responding to changes in levels of oleic acid (long-chain fatty acid, LCFA) or octanoic acid ...
Marta Librán-Pérez   +3 more
doaj   +1 more source

The Hypothalamus and Obesity [PDF]

open access: yesRecent Patents on CNS Drug Discovery, 2006
Obesity has reached epidemic proportions across the developed world. Even though there have been numerous scientific advances in terms of the understanding of the regulation of energy homeostasis, few novel anti-obesity drugs have emerged. Furthermore, those that are available have limited efficacy in producing and maintaining a weight loss beyond 10%.
Joanne A, Harrold, Jason C G, Halford
openaire   +3 more sources

Age changes in the tigroid substance of neutrons of the lateral preoptic nucleus of hypothalamus under different light modes

open access: yesJournal of Education, Health and Sport, 2021
The article presents analysis of the results of the original histochemical studies of tigroid substance of neurons of the lateral preoptic nucleus of  hypothalamus in mature and old rats under the influence of different light modes. In all observations,
R. Bulyk   +4 more
doaj   +1 more source

Genome-Wide DNA Methylation and Hydroxymethylation Changes Revealed Epigenetic Regulation of Neuromodulation and Myelination in Yak Hypothalamus

open access: yesFrontiers in Genetics, 2021
Both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) are important epigenetic modifications in neurodevelopment. However, there is little research examining the genome-wide patterns of 5mC and 5hmC in brain regions of animals under natural high-
Zhixin Chai   +8 more
doaj   +1 more source

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1998
We describe a hypothalamus-specific mRNA that encodes preprohypocretin, the putative precursor of a pair of peptides that share substantial amino acid identities with the gut hormone secretin.
L. Lecea   +14 more
semanticscholar   +1 more source

Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus

open access: yesNature Communications, 2020
The neuroendocrine hypothalamus is the central regulator of vital physiological homeostasis and behavior. However, the cellular and molecular properties of hypothalamic neural progenitors remain unexplored.
Xin Zhou   +10 more
semanticscholar   +1 more source

Role of hypothalamus function in metabolic diseases and its potential mechanisms [PDF]

open access: yesPeerJ
The hypothalamus, a crucial neuroendocrine regulatory center, plays a significant role in the occurrence and development of metabolic diseases. Recent advances in molecular biology and imaging technology have facilitated a better understanding of the ...
Xinyu Zhang   +4 more
doaj   +2 more sources

A Molecular Census of Arcuate Hypothalamus and Median Eminence Cell Types

open access: yesNature Neuroscience, 2017
The hypothalamic arcuate–median eminence complex (Arc-ME) controls energy balance, fertility and growth through molecularly distinct cell types, many of which remain unknown. To catalog cell types in an unbiased way, we profiled gene expression in 20,921
John N. Campbell   +12 more
semanticscholar   +1 more source

Exogenous spermidine affects polyamine metabolism in the mouse hypothalamus

open access: yesOpen Life Sciences, 2021
Spermidine is important for the hypothalamic control of pituitary secretion of hormones involved in neuroendocrine functions in mammals. In this study, the effect of exogenous spermidine on the expression of genes and proteins related to polyamine ...
Jiang Dongmei   +3 more
doaj   +1 more source

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