Results 201 to 210 of about 302,233 (277)

Bile Acids as Selective Gatekeepers of Dietary Lipid Absorption: Mechanistic Insights and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Their work provides evidence in murine models that the bile acid pool may function as a tunable filter whose selectivity for different fatty acids depends on bile acid concentration and composition. This framework suggests a selective decoupling of the absorption of excessive saturated fatty acids (SFAs) from that of beneficial polyunsaturated
Hao Wang, Yue Yang, Yulong Zhang, Yinling Li, Xuemei Ma, Haitao Wang   +5 more
wiley   +1 more source

Impact of adverse postnatal environment on emotional regulation and neuroimmune function in adolescent rats prenatally exposed to alcohol. [PDF]

Neurobiol Stress
Holman PJ, Vella VR, Baglot SL, Yeates D, Ubi P, Weinberg J, Bodnar TS, Raineki C.   +7 more
europepmc   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

Research Advances of Neuroregulatory Effects of Dietary Polyphenols on Obesity Complications. [PDF]

Nutrients
Han T, Wei L, Gu W, Zheng S, Du Y, Ge H, Li D, Xie Z.   +7 more
europepmc   +1 more source

Exploring the Role of Dysregulated Arousal in the Relationship Between Trauma and Addictive Behaviors Among College Students

Journal of Counseling &Development, EarlyView.
ABSTRACT The relationship between trauma and addictive behaviors is well‐established, yet factors mediating this relationship remain understudied. Given the prevalence of addictive behaviors among collegiate populations, we used path analysis to explore the mediating role of arousal dysregulation in the relationship between childhood trauma and a ...
Amanda L. Giordano, Kate M. Dorrough, Deborah L. Smith, Peitao Zhu   +3 more
wiley   +1 more source

Resolving forebrain developmental organisation by analysis of differential growth patterns. [PDF]

Nat Commun
Manning E, Chinnaiya K, Furley C, Kim DW, Blackshaw S, Placzek M, Place E.   +6 more
europepmc   +1 more source

Evaluating Brief Behavioural Activation for depression in adolescents with acquired brain injury using a single‐case experimental design

JCPP Advances, EarlyView.
Abstract Background Adolescents who have had an acquired brain injury (ABI) commonly experience depression. Brief Behavioural Activation (Brief BA) is a successful, values‐based intervention for managing depression in neurotypical adolescents. This study investigated the effectiveness of Brief BA, using a single‐case experimental design, with ...
Conor R. O’Brien, Jenny Limond, Shirley Reynolds, Laura Pass, Anna‐Lynne R. Adlam   +4 more
wiley   +1 more source

Research Note: An in vitro hypothalamic slice culture model from adult geese for investigating light-mediated regulation of avian reproduction. [PDF]

Poult Sci
Liu J, Du J, Feng Y, Chen X, Mei H, Guo B, Dai Z, Zhu H.   +7 more
europepmc   +1 more source

Interventions for pre‐school children in foster care: A systematic review of the foster carer and system level outcomes from randomised controlled trials

JCPP Advances, EarlyView.
Abstract Background Children in foster care are at increased risk of experiencing cognitive, emotional and behavioural difficulties. There is a window of opportunity for early intervention associated with developmental sensitivity in the early years. Foster carers and the systems supporting them play a central role in intervention and support for the ...
Camilla Biggs, Natalie Kirby, Megan Garside, Gloria Cheung, Fiona Turner, Nishant Jaiswal, Helen Minnis   +6 more
wiley   +1 more source

A Predictive Transcriptomic Approach to the Resveratrol-Mediated Reversal of Hypothalamic Alterations in a Mouse Model of Obesity. [PDF]

Genes (Basel)
De la Cruz-Concepción B, Mendoza-Bello JM, Beltrán-Anaya FO, Ramírez M, Flores-Cortez YA, Damian-Sánchez G, Flores-Alfaro E, Parra-Rojas I, Del Moral-Hernández O, Cruz M, Espinoza-Rojo M.   +10 more
europepmc   +1 more source