Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus
The neuroendocrine hypothalamus is the central regulator of vital physiological homeostasis and behavior. However, the cellular and molecular properties of hypothalamic neural progenitors remain unexplored.
Xin Zhou+10 more
semanticscholar +1 more source
Descending pathways from hypothalamus to dorsal motor vagus and ambiguus nuclei in the rat [PDF]
The anatomical pathways between the hypothalamus and cell groups of the lower medulla that are involved in the neural control of endocrine pancreas activity were investigated.
Bellinger+44 more
core +3 more sources
Exogenous spermidine affects polyamine metabolism in the mouse hypothalamus
Spermidine is important for the hypothalamic control of pituitary secretion of hormones involved in neuroendocrine functions in mammals. In this study, the effect of exogenous spermidine on the expression of genes and proteins related to polyamine ...
Jiang Dongmei+3 more
doaj +1 more source
Data-based Model Identification of the Hypothalamus-Pituitary-Thyroid Complex [PDF]
The thyroid gland, in conjunction with the pituitary and the hypothalamus, forms a regulated system due to their mutual influence through released hormones. The equilibrium point of this system, commonly referred to as the "set point", is individually determined.
arxiv +1 more source
Roles of estrogen receptor-alpha in mediating life span: the hypothalamic deregulation hypothesis. [PDF]
In several species caloric restriction (CR) extends life span. In this paper we integrate data from studies on CR and other sources to articulate the hypothalamic deregulation hypothesis by which estrogen receptor-alpha (ER-α) signaling in the ...
Barakat, Rita+6 more
core +1 more source
A Molecular Census of Arcuate Hypothalamus and Median Eminence Cell Types
The hypothalamic arcuate–median eminence complex (Arc-ME) controls energy balance, fertility and growth through molecularly distinct cell types, many of which remain unknown. To catalog cell types in an unbiased way, we profiled gene expression in 20,921
John N. Campbell+12 more
semanticscholar +1 more source
Identification of sex hormone-binding globulin in the human hypothalamus [PDF]
Gonadal steroids are known to influence hypothalamic functions through both genomic and non-genomic pathways. Sex hormone-binding globulin ( SHBG) may act by a non-genomic mechanism independent of classical steroid receptors.
Becchis M+35 more
core +1 more source
The Visually Related Posterior Pretectal Nucleus in the Non-Percomorph Teleost Osteoglossum bicirrhosum Projects to the Hypothalamus [PDF]
This study was done to elucidate the ancestral (plesiomorphic) condition for visual pathways to the hypothalamus in teleost fishes. Three patterns of pretectal organization can be discerned morphologically and histochemically in teleosts. Their taxonomic
Baudelot+51 more
core +1 more source
Huntingtin-associated protein 1 (Hap1) was initially identified as a brain-enriched protein that binds to the Huntington’s disease protein, huntingtin. Unlike huntingtin that is ubiquitously expressed in the brain, Hap1 is enriched in the brain with the ...
Xingxing Chen+13 more
doaj +1 more source
GABA\u3csub\u3eA\u3c/sub\u3e and excitatory amino acid receptors in dorsomedial hypothalamus and heart rate in rats [PDF]
We have previously shown that microinjection of drugs that interfere with the function of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) into the hypothalamus produces cardiorespiratory and behavioral changes resembling those seen in ...
DiMicco, Joseph A., Soltis, Robert P.
core +2 more sources